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Siliceous Raw Material Exploitation at Hort de la Boquera Site (Margalef de Monsant, Tarragona, España) : First Results from La-Icp-Ms Analysis

Research on the sourcing of siliceous raw materials in Prehistory has taken a step forward with the addition of geochemical techniques and elemental analysis to the archaeopetrological method. Counter to the macroscopic techniques, which retain an elevated subjective percentage in their results, geochemical techniques and especially LA-ICP-MS analysis generate objective, quantifiable and usable da

The late-Holocene decline of Tilia in relation to climate and human activities - pollen evidence from 42 sites in southern Sweden

Aim: The dominant role of Tilia in primeval forests of Scandinavia has long been recognized, but the timing and mechanisms for its decline have not been completely unravelled. A particular uncertainty involves the balance between climate and human activities as the drivers of the change. One reason for the uncertainty is the challenge in evaluating the past cover of the genus owing to its poorly d

Fibromodulin Interacts with Collagen Cross-linking Sites and Activates Lysyl Oxidase.

The hallmark of fibrotic disorders is a highly cross-linked and dense collagen matrix, a property driven by the oxidative action of lysyl oxidase. Other fibrosis-associated proteins also contribute to the final collagen matrix properties, one of which is fibromodulin - its interactions with collagen affect collagen cross-linking, packing, and fibril diameter. We investigated the possibility that a

The subtle nature of Facebook politics: Swedish social network site users and political participation

Sweden, with a high level of political participation and an avant-garde position regarding internet access, broadband and social media penetration in the population, is a critical case for studying social media in relation to political participation. Three types of users – members of political parties, members of interest organizations, and non-members – are interviewed in focus groups about their

Identification of the major phosphorylation sites for protein kinase C in kit/stem cell factor receptor in vitro and in intact cells

The c-kit-encoded tyrosine kinase receptor for stem cell factor (Kit/SCFR) is crucial for the development of hematopoietic cells, melanoblasts, and germ cells. Ligand stimulation of Kit/SCFR leads to receptor dimerization and autophosphorylation on tyrosine residues. We recently showed, that protein kinase C (PKC) acts in an SCF-stimulated negative feedback loop, which controls Kit/SCFR tyrosine k

E-mobility charging sites. Assessment of power system impacts, consumption patterns and feasibility aspects to explore a new business opportunity.

Electrification of energy demand is seen as one of the key elements of energy transition toward decarbonisation. E-mobility is one main side of the electrification process, and it is considered as a crucial way to reduce the emissions of the transport sector. A core element for a widespread adoption of electric vehicles (EVs) is the deployment of the charging infrastructure, and installing a micro

Site localisation on bacterial surface proteins using super resolution imaging

I snart 500 år har människan använt sig av diverse optiska instrument för att betrakta sådant som inte är möjligt att se med blotta ögat. Teleskop har använts för att studera himlakroppar och mikroskop för att exempelvis undersöka små biologiska beståndsdelar. Det finns idag många olika metoder inom optisk mikroskopi men samtliga följer en liknande grundprincip. Objektet som ska avbildas exponerasSeveral significant pathogenic bacteria exhibit surface proteins that bind human antibodies, preventing them from being recognized by the human immune system. These bacteria are thus protected from elimination and can survive in the host organism. One common such bacteria is the Streptococcus pyogenes that exhibits the antibody binding M protein on its surface. Streptococcus pyogenes causes more t