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The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity

Despite the recent clinical success of T cell checkpoint inhibition targeting the CTLA-4 and PD-1 pathways, many patients either fail to achieve objective responses or they develop resistance to therapy. In some cases, poor responses to checkpoint blockade have been linked to suboptimal CD28 costimulation and the inability to generate and maintain a productive adaptive anti-tumor immune response.

Dry release of suspended nanostructures

A dry release method for fabrication of suspended nanostructures is presented. The technique has been combined with an anti-stiction treatment for fabrication of nanocantilever based nanoelectromechanical systems (NEMS). The process combines a dry release method, using a supporting layer of photoresist which is removed using oxygen ashing in a reactive ion etcher (RIE), with CHF3 plasma induced de

The impact of sub-cellular location and intracellular neuronal proteins on properties of GABA(A) receptors

Most studies of GABA(A) receptor accessory proteins have focused on trafficking, clustering and phosphorylation state of the channel-forming subunits and as a result a number of proteins and mechanisms have been identified that can influence the GABA(A) channel expression and function in the cell plasma membrane. In the light of a growing list of intracellular and transmembrane neuronal proteins s

Gång på gång: En analys av rekvisitet “upprepad kränkning” vid grov kvinnofridskränkning

Grov kvinnofridskränkning infördes i svensk rätt 1998 för att möta ett rättsskyddsbehov som tidigare straffbestämmelser inte förmådde tillgodose. Syftet var att straffrättsligt synliggöra den systematiska karaktären av våld och kränkningar som många kvinnor utsätts för i nära relationer. Genom att kriminalisera ett mönster av gärningar, snarare än enstaka händelser, har lagstiftaren försökt fånga Gross violation of a woman’s integrity was introduced into Swedish law in 1998 to address a legal protection gap that previous criminal provisions failed to cover. The aim was to legally acknowledge the systematic nature of abuse and repeated violations that many women are subjected to in close relationships. By criminalising a pattern of acts rather than isolated events, the legislator intended t

Rod-Shaped Monocytes Patrol the Brain Vasculature and Give Rise to Perivascular Macrophages under the Influence of Proinflammatory Cytokines and Angiopoietin-2

The nervous system is constantly infiltrated by blood-derived sentinels known as perivascular macrophages. Their immediate precursors have not yet been identified in situ and the mechanism that governs their recruitment is mostly unknown. Here, we provide evidence that CD68 (+)GR(-) monocytes can give rise to perivascular macrophages in mice suffering from endotoxemia. After adhesion to the endoth

Philopatric predisposition to predation-induced ecological traps: habitat-dependent mortality of breeding eiders

Because population size is sensitive to changes in adult survival, adult survival may be buffered against environmental variability. Philopatry may be adaptive in changing environments, but it could also constrain breeding habitat selection under changing conditions such as shifting predation regimes. Habitat preference and quality could become decoupled in long-lived philopatric species that evol

Retreat. Dwell. Rehabilitate. Educate.

Iceland is known for its remote location and rough beauty. In their seclusion, the Icelanders have built an independent and peaceful country. They are undeniably a very unique nation, where police officers are not allowed to carry guns, except on special occasions. The society displays a relaxed attitude towards prisons, which are built without concrete walls around. However, faced with the immens

Spatial Audio Training

A skills development initiative carried out by IAC. In this 3 day-training, we will explore spatial audio at an introductory level. It is aimed at those who have experience in working with sound art and want to explore the tools available for creating Spatial Audio pieces. The focus will primarily be on binaural headphone listening with the potential for presentation through larger speaker systems

https://www.iac.lu.se/spatial-audio-training - 2026-06-04

No title

Although gender inclusive writing is widely polarised in public opinion, the exact causes of reluctance towards its use are not always clear. We explore the link between attitudes towards inclusive writing and different factors, such as the level of linguistic or historical knowledge of inclusive writing. We also measured the political orientation of the respondents, as well as their views on the

Francoise Lamnabhi-Lagarrigue

French control theorist and expert in uncertain nonlinear systems and hybrid systems (b. 1953) Françoise Lamnabhi-Lagarrigue, a distinguished French professor emeritus and CNRS research fellow, is best known for her theoretical advances in analyzing and controlling complex nonlinear systems and their application in power and neural networks. Affiliation: French National Centre for Scientific Resea

https://www.control.lth.se/collaboration-and-outreach/female-influencers-automatic-control/historical-female-influencers-automatic-control/francoise-lamnabhi-lagarrigue - 2026-06-03

Lidija Lindoff

Academic advisor Contact details Email: lidija [dot] lindoff [at] svet [dot] lu [dot] se Phone: +46 46 222 89 38Organisation Department of Political Science Room number: 231B Service point: 31 Study councellingYou are welcome to come by my office for counselling, if I am free I will help you. You are welcome to contact me to book a counselling session and advice. I also offer professional coaching

https://www.svet.lu.se/en/lidija-lindoff - 2026-06-04

Nymu utbildningsplaner samlingsdokument piano mas

36 1. IDENTIFIKATION Programmets namn och inriktning: musikerutbildning, piano. Omfattning i högskolepoäng: 120. Nivå: Avancerad nivå (A). Programkod: KAMUS: Inriktning: PIAN. 2. BESLUTSUPPGIFTER Utbildningsplanen är reviderad och beslutad av konstnärliga fakul- tetsstyrelsen den 18 oktober 2017. Den reviderade utbildningspla- nen träder i kraft HT-17. 3. PROGRAMBESKRIVNING Musikerutbildning, pian

https://www.mhm.lu.se/sites/mhm.lu.se/files/nymu_utbildningsplaner_samlingsdokument_piano_mas.pdf - 2026-06-05

Schema mven24 ht19x

MILJÖVETENSKAP Preliminärt schema MVEN24 Kurs: Tillämpad Miljövetenskap Kursansvarig: Håkan Wallander Lärare: Deniz Koca , Radhlinah Aulin , Per Erik Isberg , Linda Lundmark Lokaler: Vitmossan Litteratur: Ingen Studieteknik: Läs om studieverkstaden Studenträttigheter: Läs om dina rättigheter och skyldigheter som student Likabehandling: Läs Lunds Universitets likabehandlingsplan för studenter Pedag

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/schema_mven24_ht19x.pdf - 2026-06-05

Inga Persson

Professor emerita Kontaktinformation E-post: inga [dot] persson [at] nek [dot] lu [dot] se Telefon: +46 46 222 95 47Organisation Nationalekonomiska institutionen Rumsnummer: EC1:267 Hämtställe: 10 WebbplatsInga Perssons profil i Lunds universitets forskningsportalAndra roller Professor emerita Centrum för ekonomisk demografi Publikationer Visar av publikationer. Sorterade efter år och sen titel. F

https://www.ehl.lu.se/inga-persson - 2026-06-04

Blood-based omic profiling supports female susceptibility to tobacco smoke-induced cardiovascular diseases

We recently reported that differential gene expression and DNA methylation profiles in blood leukocytes of apparently healthy smokers predicts with remarkable efficiency diseases and conditions known to be causally associated with smoking, suggesting that blood-based omic profiling of human populations may be useful for linking environmental exposures to potential health effects. Here we report on