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Effect of a continuous trauma quality improvement programme on mortality in urban India: a non-randomised controlled trial

Background Trauma is the leading cause of quality-related mortality in low- and middle-income countries, with an estimated two million preventable deaths each year. Although trauma quality improvement programmes have been utilised in high-income countries for more than three decades, there is no high-level evidence of their effect on patient outcomes. We aimed to assess whether implementing a cont

Dosimetric and Clinical Predictors for Acute and Late Gastrointestinal Toxicity Following Chemoradiotherapy of Locally Advanced Anal Cancer

Aims: To analyse dosimetric and clinical predictors for acute and late gastrointestinal toxicity following chemoradiotherapy of anal cancer. Materials and methods: Consecutive patients with locally advanced (T2 ≥4 cm – T4 or N+) anal cancer were selected from an institutional database (n = 114). All received intensity-modulated radiotherapy with concomitant 5-fluorouracil and mitomycin C. Gastroin

Media Industries and Audience Research : an analytic dialogue on the value of engagement

This chapter offers a reflection on the value of dialogue across media industries and academia in enhancing understanding of audience engagement and disengagement with media. The basis for this reflection is an industry-academic collaborative project between Lund University and Endemol Shine. The Media Experiences project conducted production and audience research on a range of drama and reality e

Effects of a culturally adapted lifestyle intervention on cardio-metabolic outcomes : a randomized controlled trial in Iraqi immigrants to Sweden at high risk for Type 2 diabetes

Background andAims Middle-Eastern immigrants constitute a growing proportion of the Swedish population and are at high risk for Type 2 diabetes. This calls for a more proactive preventive approach for dealing with diabetes risk in this target group. The aim was to test the effect of a culturally adapted lifestyle intervention programme on changes in lifestyle habits and cardio-metabolic outcomes c

The importance of including secondary effects when defining the system boundary with life cycle perspective : Case study for design of an external wall

Life cycle assessment and life cycle cost analysis are suitable tools in trying to minimize environmental impact and cost. To get reliable results it is crucial to set up correct system boundaries for the investigation, but it is often difficult to understand a complex products system because of the cascade effects of consequences that can be induced even by small changes. In this paper the effect

Fragments of Late Eocene Earth-impacting asteroids linked to disturbance of asteroid belt

The onset of Earth's present icehouse climate in the Late Eocene coincides with astronomical events of enigmatic causation. At similar to 36 Ma ago the 90-100 km large Popigai and Chesapeake Bay impact structures formed within similar to 10-20 ka. Enrichments of He-3 in coeval sediments also indicate high fluxes of interplanetary dust to Earth for 2 Ma. Additionally, several medium-sized impact st

Optimal prediction of catastrophes in autoregressive moving-average processes

Abstract. This paper presents an optimal predictor of level crossings, catastrophes, for autoregressive moving-average processes, and investigates the performance of the predictor. The optimal catastrophe predictor is the predictor that gives a minimal number of false alarms for a fixed detection probability. As a tool for evaluating, comparing and constructing the predictors a method using operat

A comparative study of factors affecting the external stakeholder management process

There is a natural tendency for stakeholder groups to try to influence the implementation of construction projects in line with their individual concerns and needs. This presents a challenge for construction project managers in analysing and managing these various concerns and needs in a stakeholder management process falling within the limits of the project. The aim of the research presented here

Age and metallicity gradients in the Galactic Bulge - A differential study using HST/WFPC2

The Galactic Bulge has long been assumed to be a largely old stellar population. However, some recent studies based on observations with the HST WF/PC-1 and WFPC2 of stars in the Galactic Bulge have concluded that the old population may not make up more then 30% of the total. Other studies using HST/WFPC2 differential studies of `Bulge' globular clusters and field stars have found the bulge to be

Defibrotide for prophylaxis of hepatic veno-occlusive disease in paediatric haemopoietic stem-cell transplantation: an open-label, phase 3, randomised controlled trial

Background Hepatic veno-occlusive disease is a leading cause of morbidity and mortality after haemopoietic stem-cell transplantation (HSCT). We aimed to assess whether defibrotide can reduce the incidence of veno-occlusive disease in this setting. Methods In our phase 3 open-label, randomised controlled trial, we enrolled patients at 28 European university hospitals or academic medical centres. El

Importance of fossil fuel emission uncertainties over Europe for CO2 modeling : model intercomparison

Inverse modeling techniques used to quantify surface carbon fluxes commonly assume that the uncertainty of fossil fuel CO2 (FFCO2) emissions is negligible and that intra-annual variations can be neglected. To investigate these assumptions, we analyzed the differences between four fossil fuel emission inventories with spatial and temporal differences over Europe and their impact on the model simula

The effect of McKenzie therapy as compared with that of intensive strengthening training for the treatment of patients with subacute or chronic low back pain - A randomized controlled trial

Study Design. A randomized controlled comparative trial with an 8-month follow-up period was conducted. Objective. To compare the effect of the McKenzie treatment method with that of intensive dynamic strengthening training in patients with subacute of chronic low back pain. Summary of Backround Data. Randomized studies indicate that the efficacy of the McKenzie method in the treatment of patients

Fluorescence microscopy for quality control in nanoimprint lithography

Fluorescence microscopy is introduced as a low cost quality control process for nanoimprint lithography. To depict imprinted structures down to 1 mum lateral size and to detect residues down to 100 nm lateral size, the standard printable polymer mr-18000 is labelled with less than 0.1 wt.% fluorescent dye. Three different types of stamps are used to determine the dependence of the shape and size o

Rapid bond rearrangement in core-excited molecular water.

The angular anisotropy of fragments created in the dissociation of core-electron excited water molecules is studied to probe the correlation between fragmentation channels, kinematics and molecular geometry. We present fragment kinetic measurements for water molecules where the inner-shell oxygen electron is excited to the unoccupied 4a1 and 2b2 valence molecular orbitals. The kinematics of indivi

Benzodiazepine and opioid dependence. Clinical and meta-analytical studies.

Popular Abstract in Swedish Livstidsprevalensen för läkemedelsberoende hos alkoholberoende patienter varierar mellan 20% och 45%. I normalbefolkningen är livstidsprevalensen av läkemedelsberoende cirka 2%; livstidsprevalensen för beroende av bensodiazepiner (BZD) respektive legala opioider (metadon exkluderat) är 0.3-0.9% respektive 0.8%. Förskrivningen av BZD har de senaste åren legat konstant elThe thesis contains 4 papers, two clinical studies and two meta-analyses. In the BZD taper study (Paper I) 21 BZD dependent (DSM-IV) patients were included for a 10-day inpatient detoxification. The average defined daily dose (DDD) was 4.7 doses. Withdrawal symptoms were not more pronounced compared to more extended detoxification procedures reported in literature. Five patients, all with concomi

Heat and mass transport in a nonlinear fixed-bed catalytic reactor: Hot spots and thermal runaway

Transient heat and mass transport in a wall-cooled tubular catalytic bed reactor is numerically investigated. A two-dimensional pseudo-heterogeneous model, accounting for transport in the solid and fluid phases, with axial and radial dispersions is used to describe transport in the reactor. The effects of inlet process conditions, viz., temperature and concentration, are investigated and their imp

It takes two to tango – making way for relevant research support services at Lund University Libraries (LUB)

I artikeln presenteras ett projekt om forskares behov av stöd, genomfört 2012, inom biblioteksnätverket Lunds universitets bibliotek (LUB). Projektet består av a) en litteraturöversikt med fokus på definitioner av och exempel på forskarstöd samt vilka behov och erfarenheter forskare själva har av forskarstöd, b) en enkätundersökning av befintlig forskarservice från biblioteken inom (LUB), ett deceThis article presents a 2012 project on researchers’ need of support at Lund University Libraries (LUB). The project was three folded with the object to identify areas where the present research support services ought to be developed and strengthened. The project contains a) a literature review focusing on definitions and examples of research support services as well as researchers’ needs and expe

Diel vertical migration in marine dinoflagellates

Popular Abstract in Swedish Den globala uppvärmningen av vår jord påverkar inte bara lufttemperaturen, utan även haven blir varmare. Dessutom förespås en ökning i nederbörd vilket kommer att göra havens ytvatten mindre salta. Temperaturförändringen och den ökade nederbörden kan leda till att skiktningen, den s.k. vertikala stratifieringen, som finns naturligt i haven blir skarpare och starkare. StIncreasing precipitation and surface water temperature due to global change may strengthen stratification in coastal regions, which could influence the behavior of dinoflagellate diel vertical migration (DVM). DVM is a behavioral mechanism by which dinoflagellates can access photosynthetically active radiation near the surface, and nutrients at depth. During this process, cells may need to cross b

I litteraturens mittfåra. Månadens bok och svensk bokmarknad under 1970-talet

Popular Abstract in Swedish Föreliggande avhandling, I litteraturens mittfåra, behandlar bokmarknad, bokklubbar och litteraturen under 1970-talet i Sverige. Bakgrunden till undersökningen är de radikala förändringar som skedde på den svensk bokmarknaden efter den genomgripande avregleringen av handeln med böcker 1970. Bokklubbarna växte från att inneha en marknadsandel på 9% 1970 till att ha 30% aThe present dissertation, I litteraturens mittfåra, deals with book trade, book clubs, and the fiction prose of the 1970s in Sweden. The background to the study is the radical change in Swedish book trade through a far-reaching deregulation of the trade in 1970. The book clubs expanded from a position where they held a 9% share of the market in 1970 to a market share of 30% in 1980.And the specifi