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OBJECTIVES: The National Board of Health and Welfare in Sweden published the national guidelines for Parkinson's Disease 2016. The aim of this study was to summarize this evidence review and development of the guidelines, focusing on the economic evaluation of device-aided therapies (deep brain stimulation, pump-based infusion of levodopa-carbidopa intestinal gel or apomorphine) for Parkinson's di

Type 1 diabetes is a chronic autoimmune disease requiring insulin treatment for survival. Prolonged duration of type 1 diabetes is associated with increased risk of microvascular complications. Although chronic hyperglycemia and diabetes duration have been considered as the major risk factors for vascular complications, this is not universally seen among all patients. Persons with long-term type 1

Background: Osteoporosis is an underdiagnosed and undertreated disease worldwide. Recent studies have highlighted the use of simple vertebral trabecular attenuation values for opportunistic osteoporosis screening. Meanwhile, machine learning has been used to accurately segment large parts of the human skeleton. Purpose: To evaluate a fully automated deep learning-based method for lumbar vertebral

While a broad spectrum of technologies is integrated in everyday life and routines, most research on ageing, health and technology has focused on attitudes toward and adoption of digital technologies including e-health, or home based monitoring systems. The aim of this study was to explore differences and similarities in attitudes and experiences with different types of technologies and developmen

BACKGROUND: Little is known about the costs of HIV care in Ethiopia.OBJECTIVE: To estimate the average per person year (PPY) cost of care for HIV patients with and without anti-retroviral therapy (ART) in a district hospital.METHODS: Data on costs and utilization of HIV-related services were taken from Arba Minch Hospital (AMH) in southern Ethiopia. Mean annual outpatient and inpatient costs and c

Objective: This paper analyses intergenerational relationships in Sweden during the corona pandemic, with a special focus on practices of care. The research question is: How is care between generations – between grandparents, adult children and grandchildren – done during pandemic conditions? Background: In Sweden, where an extensive welfare state provides affordable child- and eldercare, the coro

Binas surrande är en viktig komponent för känslan av sommar. Men, förutom många hyllmeter av litteratur om några vanliga arter av honungsbi och humlor, vet vi än idag förvånansvärt lite om många av de tjugofem tusen arter vi kallar bin. Vissa humlor överlever Grönlands minusgrader och hårda vindbyar, medan de i Amazonas snarare älskar skogens höga temperatur och fuktighet. Vissa arter bor i stora The buzzing flight of bees is a popular summer hit. Yet, outside of a few familiar species of honeybees and bumblebees, these fantastic little creatures are still mostly unknown. With about twenty-five thousand species, bees are a very diverse group. They can be found in drastically different habitats. For example, some kinds of bumblebees endure the freezing temperatures and windswept tundra of G

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent chronic liver disease globally, and can lead to hepatocellular carcinoma (HCC), a leading cause of cancer-related death. We aimed to determine the extent to which MASLD is an increasing cause of HCC in Sweden and to determine clinical characteristics associated with underlying MASLD. Using the Swedish quality re

We report the real-valued static and complex-valued quasi-static anisotropic permittivity parameters of rare-earth scandate orthorhombic single crystal GdScO3 (GSO), TbScO3 (TSO), and DyScO3 (DSO). Employing continuous-wave terahertz spectroscopy (0.2-1 THz), the complex permittivity was extracted using an anisotropic ambient-film-ambient model. Data obtained from multiple samples of the same oxid

Episodic memory formation entails the integration of diverse elements such as people, places, and objects. This process, known as binding, creates a unified memory trace that the brain maintains and retrieves as a coherent representation of the episode. Despite extensive research, the precise neural mechanisms underlying this binding process are still not fully understood. We hypothesized that the

Few studies have investigated the offspring of women with anorexia nervosa (AN). The aim of this study was to examine perinatal status, mental and physical health in the offspring of mothers with a history of AN. Fifty-one individuals with adolescent-onset AN and 51 matched controls (COMP) have been followed prospectively. Presently, 30 years after AN onset, at a mean age of 44 years, female parti

Specific ion (Hofmeister) effects in colloid and biological systems represented a scientific challenge for more than 100 years. Recently, possible applications, based on their rationalization, are emerging. Here, Cl-, SO42-, SCN- anions and Na+, K+, Mg2+ cations are added at physiological concentration (∼0.15 mol/kg) to Pluronic F127 20 wt% aqueous solutions to suitably tune phase transitions for

Brain cell structure and function reflect neurodevelopment, plasticity, and aging; and changes can help flag pathological processes such as neurodegeneration and neuroinflammation. Accurate and quantitative methods to noninvasively disentangle cellular structural features are needed and are a substantial focus of brain research. Diffusion-weighted MRS (dMRS) gives access to diffusion properties of

Background More than half of cardiovascular mortality occurs outside the hospital, mainly due to consistently low survival rates from out-of-hospital cardiac arrest. Methods This is a prospective, nested, case-control study derived from the Västerbotten Intervention Programme and the World Health Organization's Multinational Monitoring of Trends and Determinants in Cardiovascular Disease study in

Abstract in UndeterminedThis work presents a comparative study regarding wear behavior between a novel abrasion resistant cast iron, "Carbide Steel" and a number of conventional tool materials frequently used in the automotive industry. Carbide Steel is basically a high-Cr white cast iron heavily alloyed with cemented carbide. The high chromium content and additional alloying elements like WC. TiC

Objective: The novel axial flow left ventricular assist device HeartMate II was introduced into clinical practice in Europe as part of the pilot study and after CE approval in November 2005. In order to get an overview of the use and performance of the device in Europe a group of investigators was founded to compare the initial results. Methods: In a retrospective analysis of the first 101 consecu

Purpose. When performing perimetry, refracting subjects with central visual field loss, and in emmetropization studies, it is important to accurately measure peripheral refractive errors. Traditional methods for foveal refraction often give uncertain results in eccentric angles as a result of the large aberrations and the reduced retinal function. The aim of this study is therefore to compare and

Background. The Lundby Study is a longitudinal cohort study on a geographically defined population consisting of 3563 subjects. Information about episodes of different disorders was collected during field investigations in 1947, 1957, 1972 and in 1997. Interviews were carried out about current health and past episodes since the last investigation; for all subjects information was also collected fr