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A comparison of spouse and non-spouse carers of people with dementia : a descriptive analysis of Swedish national survey data

Background: Being an informal carer of a person with dementia (PwD) can have a negative effect on the carer’s health and quality of life, and spouse carers have been found to be especially vulnerable. Yet relatively little is known about the care provided and support received by spouse carers. This study compares spouse carers to other informal carers of PwDs regarding their care provision, the su

Comparison of single subject and population-based pharmacokinetics for optimizing prophylaxis with simoctocog alfa in patients with haemophilia A

Introduction: The use of pharmacokinetic assessment for optimal prophylactic dosing of factor concentrates in haemophilia has gained increasing enthusiasm over the last decade. However, blood sampling on several occasions is burdensome and limited sampling using population-based PK is appealing. Aim: To compare the pharmacokinetics and dosing recommendations for prophylaxis using six-point single

Direct and Legacy Effects of Spring Temperature Anomalies on Seasonal Productivity in Northern Ecosystems

Warmer or cooler spring in northern high latitudes will, for the most part, directly impact gross primary productivity (GPP) of ecosystems, but also carry consequences for the upcoming seasonal GPP. Spatiotemporal patterns of these legacy effects are still largely unknown but important for improving our understanding of how plant phenology is associated with vegetation dynamics. In this study, imp

Framework for a virtual nursing faculty and student learning collaboration between universities in Sweden and the United States : A theoretical paper

A sound pedagogical framework must be explored and identified to implement opportunities for collaborative learning through international exchange. This paper identifies the framework used by two universities, in Sweden and the United States. Virtual learning environments and meaningful learning activities can be constructed using web-based learning platforms. The goal for this initiative was 'int

Post-translational events in proteoglycan synthesis : Kinetics of synthesis of chondroitin sulfate and oligosaccharides on the core protein

Chondrocytes isolated from the Swarm rat chondrosarcoma were incubated in culture with [1-3H]glucose for 30 min to 8 h. Labeled proteoglycans were isolated, treated with borohydride under alkaline conditions, and the three complex sugar structures purified: N- and O-linked oligosaccharides and chondroitin sulfate chains. The amount of incorporated radioactivity into each component sugar was analyz

Framing the uncertain: The case of the IPCC

Human-induced climate change presents grave challenges to society. We have to find ways both to mitigate the changes and adapt to them. However, this is not all, for politics climate change represents a problem with large scientific uncertainties. This is evident in the Intergovernmental Panel on Climate Change (IPCC) assessment reports. In this study, scientific uncertainty is discussed and syste

Antennas and Propagation for the Ear-to-Ear Propagation Channel for Binaural Hearing Aids

We have investigated the possibility of using the 2.45 GHz ISM band for communication between binaural hearing aids. The preliminary investigations were done by FDTD simulations on a modified SAM phantom head, where we have included a simple model of the ear canal. Two different types of hearing aid placements have been investigated: in the outer ear and in the ear canal. Antennas which have been

Meaning Constitution Analysis: A Phenomenological Approach

Each and every thought, word, feeling or action of a person recele a surplus of meaning, opening on all the possible worlds accessible for him/her. A vision on those possible worlds and possibilities of action, should be of the highest interest for psychological research. Research in cross/cultural/intercultural psychology confronts the researcher to language, in conversations, narratives, writing

Green Logistics through Modal Shift - exploring the role of the transport capacity contract

Popular Abstract in Swedish För att minska CO2-utsläppen från godstransporter har politiker i Europa under de senaste tio åren framhävt att det krävs ett skifte i transportslag för europeiska transporter, från flyg- och lastbilstransporter till mer miljövänliga tåg- och sjötransporter. Intermodala väg-järnvägstransporter, där en kombination av tåg och lastbil använts för att förflytta lösa standarAmong policy-makers in Europe the modal shift - a shift från polluting modes of freight transport to less polluting modes - has been a popular suggestion for reducing CO2-emissions of transportation. In particular, intermodal road-rail solutions, where a combination of road and rail transport is utilized to move trailers and containers, have been stressed as an important measure to reach de desire

No evidence, no problem? A critical interpretive synthesis of the vulnerabilities to and experiences of sexual violence among young migrants in Europe : No evidence, no problem?

Background: Growing evidence indicates that young migrants are particularly vulnerable to sexual violence, however most research has focused on instances of sexual violence occurring in conflict zones and during transit. Much less attention has been given to the vulnerabilities to and experiences of sexual violence among young migrants in Europe.Objectives: To understand the scientific evidence re

Obstructive Sleep Apnea and Pulmonary Hypertension : A Chicken-and-Egg Relationship

Obstructive sleep apnea (OSA) is characterized by repeated episodes of upper airway obstruction during sleep, and it is closely linked to several cardiovascular issues due to intermittent hypoxia, nocturnal hypoxemia, and disrupted sleep patterns. Pulmonary hypertension (PH), identified by elevated pulmonary arterial pressure, shares a complex interplay with OSA, contributing to cardiovascular com

Life’s Essential 8 is inversely associated with high-sensitivity C-reactive protein

Life’s Essential 8 (LE8) is a score that includes modifiable risk factors for cardiovascular disease. Four health behaviors (diet, physical activity, nicotine exposure and sleep health) and four health factors (non-HDL cholesterol, blood glucose, blood pressure and body mass index) are included. These modifiable risk factors promote inflammation, and inflammation is one of the biological mechanism

Associations between the spread of COVID-19 and end-of-life circumstances in the non-infected population of Sweden

Aims: Since its outbreak in 2020, the COVID-19 pandemic has directly caused the premature death of millions. However, indirect consequences, such as social restrictions, have affected a far greater number. We explored the association between the spread of COVID-19 and end-of-life circumstances in the infected and non-infected population in Sweden. Methods: In this descriptive, population-based, ob

The Impact of Hospital Volume on Surgical Outcome in Patients with Rectal Cancer

PURPOSE: This study was designed to investigate, in a population-based setting, the surgical outcome in patients with rectal cancer according to the hospital volume. METHODS: Since 1995 all patients with rectal cancer have been registered in the Swedish Rectal Cancer Registry. Hospitals were classified, according to number treated per year, as low-volume, intermediate-volume, or high-volume hospit

Hygroscopic behavior of aerosol particles emitted from biomass fired grate boilers

This study focuses on the hygroscopic properties of submicrometer aerosol particles emitted from two small-scale district heating combustion plants (1 and 1.5 MW) burning two types of biomass fuels (moist forest residue and pellets). The hygroscopic particle diameter growth factor (Gf) was measured when taken from a dehydrated to a humidified state for particle diameters between 30 350 nm (dry siz

Comparison of ethyl glucuronide in hair with phosphatidylethanol in whole blood as post-mortem markers of alcohol abuse

Ethyl glucuronide (EtG) is a direct metabolite of ethanol and has been used as a marker of alcohol abuse in both urine and hair. This study investigated the value of EtG testing in post-mortem hair for diagnostic improvement of alcohol abuse in forensic medicine. Material from 70 consecutive medico-legal autopsies was collected in accordance with the recommendations on ethics by the Swedish Nation

The effect of shaking regime on the rate and extent of enzymatic hydrolysis of cellulose

In an attempt to elucidate the effect of mixing on the rate and extent of enzymatic hydrolysis of cellulosic substrates, alpha -cellulose was hydrolysed using a commercial cellulase preparation at varying levels of substrate concentration (2.5,5 and 7.5% (w/v)) and by using three shaking regimes: continuous at low-speed (25 rpm), continuous at high-speed (150 rpm) and an intermittent regime compri

Independent prognostic value of angiogenesis and the level of plasminogen activator inhibitor type I in breast cancer patients

Tumour angiogenesis and the levels of plasminogen activator inhibitor type I (PAI-I) are both informative prognostic markers in breast cancer. In cell cultures and in animal model systems, PAI-I has a proangiogenic effect. To evaluate the interrelationship of angiogenesis and the PAI-I level in breast cancer, we have evaluated the prognostic value of those factors in a total of 228 patients with p

Anthropometric Measures, Physical Activity, and Risk of Glioma and Meningioma in a Large Prospective Cohort Study

Body fatness has been associated with increased risk of a number of hormone-dependent cancers. Recent studies suggest that body mass index (BMI) may be related to meningiomas, which are more common in women than men, and for which estrogens are believed to play a role. Using data from a large European propective cohort, 203 incident cases of meningioma and 340 cases of glioma were included in the