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Leukocyte migration into the epithelial compartment is an important feature in the active phase of mycobacterial infections. In this study, we used the Transwell model to investigate the mechanisms behind mycobacteria-induced leukocyte recruitment and investigated the role of TLR2 and TLR4 in this process. Infection of epithelial cells resulted in significantly increased secretion of the neutrophi
Learning from incidents is important for improving safety. Many companies spend a great deal of time and money on such learning procedures. The objectives of this paper are to present some early results from a project aimed at revealing weaknesses in the procedures for learning from incidents and to discuss improvements in these procedures, especially in chemical process industries. The empirical
Eutrophication of the Baltic Sea has in Sweden led to the initiation of government schemes aiming to increase wetland areas in agricultural regions and thereby reduce nutrient transport to the sea. Landowners play a significant role as providers of this ecosystem service and are currently offered subsidies to cover their costs for constructing and maintaining wetlands. We undertook a grounded theo
The environmental impact of an extended property close source-separation system for solid household waste (i.e. a systems for collection of recyclables from domestic properties) is investigated in a residential area in southern Sweden. Since 2001, households have been able to source-separate waste into six fractions of dry recyclables and food waste sorting. The current system was evaluated using
In this work, a first-order upwind and a high-order flux-limiter schemes for solving the advection–diffusion equation on unstructured grids were evaluated. The numerical schemes were implemented as a module of an unstructured two-dimensional depth-averaged circulation model for shallow lakes (IPH-UnTRIM2D), and they were applied to the Guaíba River in Brazil. Their performances were evaluated by c
Budburst models have mainly been developed to capture the processes of individual trees, and vary in their complexity and plant physiological realism. We evaluated how well eleven models capture the variation in budburst of birch and Norway spruce in Germany, Austria, the United Kingdom and Finland. The comparison was based on the models performance in relation to their underlying physiological as
Early-onset dominantly inherited forms of Alzheimer's disease (AD) are rare, but studies of such cases have revealed important information about the disease mechanisms. Importantly, mutations in amyloid precursor protein (APP), presenilin 1 (PSEN1) and PSEN2, alter the APP processing and lead to an increased amyloid beta-peptide (A beta) 42/40 ratio. This, together with other studies on pathogenic
Over the last years an expanding family of small RNAs (i.e. microRNAs, siRNAs and piRNAs) was recognized as key players in diverse forms of gene silencing and chromatin organization. Effectors functions of these small RNAs are achieved through ribonucleoprotein (RNP) complexes containing at their center an Argonaute/Piwi protein. Although these proteins and their small RNA-associated machinery can
Popular AbstractAvhandlingen analyserar sentida urbana förändringar ur perspektivet kampen om rummet, här kallat 'space wars'. Fokus är på investeringsflöden inom den kommersiella fastighetsmarknaden, förändringar inom urbanpolitik, förändring inom stadens socialgeografi, och relationer mellan dessa tre aspekter. Empiriskt bygger avhandlingen på studier av data rörande utländska investeringar, arkThe dissertation analyzes recent urban transformations through the lens of space wars. The main focus is on investment flows in the commercial property market, changes in urban governance and changes in social geography, and how these three aspects are related. Drawing on cross border investment data, archive studies, interviews with key actors and street walking experiences in Copenhagen, Lisbon
The thesis aims at deconstructing the sustainable tourism paradigm: can tourism be "a global strategy for sustainable development", as the tourist industry claims? And will developing countries in particular profit from tourism development?To most international organizations and institutions (from the World Wide Fund for Nature to The World Bank), tourism, if carefully managed, is a positive, sust
Popular Abstract in Swedish Avhandlingen presenterar en experimentell studie av urlakning av betong orsakat av vatten som tränger igenom betongen, eller av diffusion av joner till vatten på uppströmssidan. Urlakningsförloppet och dess effekter modelleras med finita-element-metoden.The present report presents an experimental study of leaching of concrete caused by water percolating through the concrete, or by diffusion from concrete to external water in contact. An apparatus was designed and constructed in which de-ionised water could be forced, by external pressure, through a number of concrete specimens of differing characteristics. It was found that, whereas the initial w
CdTe nanocrystalline powder was synthesized by chemical process. The structure of CdTe nanocrystalline was investigated by means of X-ray diffraction (XRD) technique, energy-dispersive X-ray analysis (EDAX) spectrum and transmission electron microscopy (TEM). The selected area electron diffraction (SAED) study confirms the crystallinity of the CdTe nanocrystalline. Some structural parameters such
This is a descriptive study of tendon pathology with different structural appearances of repair tissue correlated to immunolocalization of cartilage oligomeric matrix protein (COMP) and type I and III collagens and expression of COMP mRNA. The material consists of nine tendons from seven horses (5-25 years old; mean age of 10 years) with clinical tendinopathy and three normal tendons from horses (
Reactions in aqueous solution under hydrothermal conditions between (+/-)-2,3-dimethylsuccinic acid and lanthanide chlorides lead to two different isostructural types with chemical formulas [Ln(2)(C6H8O4)(3)(H2O)(2)] Ln(III) = Pr-Eu (except Pm) (Type I, compounds 1-4) and [Ln(2)(C6H8O4)(3)] Ln(III) = Tb-Yb (except Tm) (Type II, compounds 5-9). The crystal structure has been solved for the Pr (1)-,
We report the growth of ultrathin diamond nanorods (DNRs) by a microwave plasma assisted chemical vapor deposition method using a mixture gas of nitrogen and methane. DNRs have a diameter as thin as 2.1 nm, which is not only smaller than reported one-dimensional diamond nanostructures (4-300 nm) but also smaller than the theoretical value for energetically stable DNRs. The ultrathin DNR is encapsu
The development of a model for any energy system is required for proper design, operation or its monitoring. Models based on accurate mathematical expressions for physical processes are mostly useful to understand the actual operation of the plant. However, for large systems like combined heat and power (CHP) plants, such models are usually complex in nature. The estimation of output parameters us
The variations in atmospheric radiocarbon (C-14) concentration during the last 50 000 years can be attributed to changes in the C-14 production rate (due to changes in solar activity, the geomagnetic field and/or interstellar galactic cosmic ray flux) and to changes in the global carbon cycle. The relative contributions of these processes is the subject of current debate. Although the discrepancie
Results of a recent European research project MAnaging Speeds of Traffic on European Roads (MASTER) are presented. Speed management is described as a two-step process where target speeds for different kinds of roads are determined first, and then various measures and tools are applied in order to adopt such speed. Current practice and main problems in speed management are described. The various im
A considerable amount of mineral particles are found to have a plate-like shape. The work in this thesis concerns theoretical investigations, using Monte Carlo method, of the properties of such particles in aqueous solutions. The objectives were first to create a model that could capture the essential physics of clay suspensions and also to understand the role of thermodynamics in certain chemical
Popular Abstract in Swedish I början av 1980-talet rökte ungefär var tredje gravid kvinna i Sverige. Detta innebar att rökning under graviditet var lika vanligt förekommande som rökning bland den vuxna befolkningen i övrigt. Sedan dess har rökningen bland gravida minskat markant och idag är det ungefär 10-12% som röker vid inskrivningen på mödravårdscentralen. Rökning under graviditet är en av deA smoking cessation program targeting pregnant women and their partners was monitored during 17 years and subjected to several substudies. All women in Blekinge, who gave birth in the months of September during the period 1984 to 2000, were asked to fill out a questionnaire, anonymously, about their smoking habits before and during pregnancy. During these years a long-term educational programme co
