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Popular Abstract in Swedish Den medicinska termen sepsis, "blodförgiftning" orsakas av bakterier i blodet. Symptombilden kan variera från tämligen lindriga förlopp till septisk shock, som har en hög dödlighet. Vid sepsis och septisk shock aktiveras olika kroppsegna system såsom koagulations- och komplementsystemet. Många mekanismer medieras av så kallade cytokiner. Dessa budbärarmolekyler byggs upPurified bacterial cell wall components peptidoglycan and teichoic acid were isolated from staphylococcal species S. aureus and/or S. epidermidis and tested for their ability to induce cytokine release from plastic-adherent human monocytes. Both cell wall components dose-dependently induced TNF-alpha, interleukin-1beta, and interleukin-6 release, peptidoglycan being more potent than teichoic acid.

Thermal stability of food-borne pathogens in apple cider is influenced by the composition of the product. As a preliminary step to determine the effect of pasteurization of apple cider on the survival of Escherichia coli O157:H7, a study was carried out to characterize apples and unpasteurized apple cider produced by a Guelph area orchard. Samples of commercial unpasteurized cider and the constitu

Popular Abstract in Swedish Abstract Hydrogen embrittlement is a degradation process of mechanical/tribological properties (toughness, wear etc.) of mating steel surfaces. This is caused by the presence and interaction of hydrogen with applied stresses. Therefore, it is important to quantify the hydrogen content which could be dissolved under applied stresses in steel. Water contamination of lubriAbstract Hydrogen embrittlement is a degradation process of mechanical/tribological properties (toughness, wear etc.) of mating steel surfaces. This is caused by the presence and interaction of hydrogen with applied stresses. Therefore, it is important to quantify the hydrogen content which could be dissolved under applied stresses in steel. Water contamination of lubricants is often considered as

With the exponential growth of the World Wide Web, automated subject classification of Web pages has become a major research issue in information and computer sciences. Organizing Web pages into a hierarchical structure for subject browsing is gaining more recognition as an important tool in information-seeking processes. In this thesis, different automated classification approaches, focusing on

Popular Abstract in Swedish Råttans urinblåsa har studerats ur olika aspekter, sedan antingen ett standardiserat avflödeshinder åstadkommits eller hälften av urinblåsans nervförsörjning avlägsnats. Avflödeshindret har åstadkommits genom att en silkestråd knutits runtom urinröret så att det försnävats. Genom att en knappt mm-vid metallstav knutits om samtidigt och sedan avlägsnats, har graden av avMedian micturition volume decreased early after partial outlet obstruction, 24 hrs total obstruction and hemidenervation. Degeneration release of transmitter may explain this, assuming that bladder wall distension causes nerve degeneration. Micturition pressure decreased simultaneously in the partially denervated and 24 hrs obstructed groups, probably due to the reduced number of functionally inta

Popular Abstract in Swedish Gastroesofageal refluxsjukdom är ett tillstånd som kännetecknas av att magsyra åker upp i matstrupen (reflux). Reflux är ett normalt fenomen som förekommer hos alla individer utan att orsaka symtom eller vävnadsskador. Hur detta normaltillstånd utvecklas till ett sjukdomstillstånd är ej helt klarlagt. Reflux förhindras normalt av en barriär vid övergången mellan matstruThere is a persisting controversy concerning the definition, etiology and pathogenesis of Barrett's esophagus. The dramatic and parallel increase in the incidence of esophageal and junctional adenocarcinoma over the past decades justifies an evaluation of the pathophysiology of premalignant metaplastic changes of the esophagus and the gastroesophageal junction. Patients were evaluated with upper G

Popular Abstract in Swedish Reumatoid artrit (kronisk ledgångsreumatism; RA) är en inflammatorisk sjukdom där lederna är det primära målorganet. Spondylartropatier är ett gemensamt namn för ett flertal kroniska inflammatoriska sjukdomar med många gemensamma tecken som till exempel: inflammatorisk ryggsmärta, inflammationer i leder, senskidor, muskelfästen, förekomst av "orvfingrar/-tår". Orsaken/eAbstract The treatment of arthritis has undergone a dramatic change since biological agents targeting specific mediators of the disease process have been introduced. Tumour necrosis factor (TNF) antagonists have been shown to reduce signs and symptoms of disease and to retard the development of tissue damage in the majority of patients. This thesis focuses on clinical, immunological and biochemic

We have used transient photoinduced absorption on femtosecond to nanosecond time scales as well as delayed fluorescence up to microseconds to study the photogeneration and recombination of charges in thin films of the alternating polyfluorene copolymer poly[2,7-(9,9-dioctylfluorene)-alt-5,5-(4('),7(')-di-2-thienyl-2('),1(') ,3(')-benzothiadiazole)]. We interpret the results using a coupled rate eq

Popular Abstract in Swedish Barns villkor i stadsmiljö är ett viktigt tema för förståelsen av den moderna barndomen. Barn har emellertid sällan tillfrågats om sin syn på stadens miljövillkor. Avhandlingens syfte är sammanfattningsvis: * Att beskriva de sakkunnigas försök att skapa goda uppväxtvillkor för barn i stadsmiljö, utifrån det jag sammanfattande benämner "de för barnen tänkta perspektivenChildren's conditions in urban environments are an important theme for understanding modern childhood, yet children have rarely been asked about their views of urban childhood conditions. The aim of the dissertation is: To describe the experts' attempts to create good conditions for growing up in an urban environment. This is summed up as "perspectives thought out for the children". To investiga

This thesis aimed to examine the relationship between climate and atmospheric CO2 concentrations through rapid climate changes during the Holocene. Climate was reconstructed using high-resolution, radiocarbon dated, lake sediment geochemical proxies (magnetic susceptibility, loss-on-ignition, total carbon/nitrogen/sulphur determinations and biogenic silica), vegetational reconstruction (pollen ana

Proteins G and PAB are bacterial albumin-binding proteins expressed at the surface of group C and G streptococci and Peptostreptococcus magnus, respectively. Repeated albumin-binding domains, known as GA modules, are found in both proteins. The third GA module of protein G from the group G streptococcal strain G148 (G148-GA3) and the second GA module of protein PAB from P.magnus strain ALB8 (ALB8-

The Commission of the European Communities (CEC) research project "Predictivity and optimisation in medical radiation protection" addressed fundamental operational limitations in existing radiation protection mechanisms. The first part of the project aimed at investigating (1) whether the CEC image quality criteria could be used for optimization or a radiographic process and (2) whether significan

Development of relevant models of Parkinson's disease (PD) is essential for a better understanding of the pathological processes underlying the human disease and for the evaluation of promising targets for therapeutic intervention. To date, most pre-clinical studies have been performed in the well-established rodent and non-human primate models using injection of 6-hydroxydopamine (6-OHDA) or 1-me

The electrocardiogram (ECG) remains the most immediately accessible and widely used diagnostic tool for guiding emergency treatment strategies. The ECG recorded during acute myocardial ischemia is of diagnostic, therapeutic, and prognostic significance. In patients with myocardial ischemia as a result of decreased blood supply, the initial 12-lead ECG typically shows (1) predominant ST-segment ele

Remote sensing provides spatially and temporally continuous measures of forest reflectance, and vegetation indices calculated from satellite data can be useful for monitoring climate change impacts on forest tree phenology. Monitoring of evergreen coniferous forest is more difficult than monitoring of deciduous forest, as the new buds only account for a small proportion of the green biomass, and t

Objective: The vagina makes a major contribution to the normal female sexual response cycle. An increase in vaginal blood flow is considered a key event in the mechanism of sexual arousal. Recent research has focused mainly on the cyclic GMP pathway and phosphodiesterase type 5 (PDE5, cyclic GMP specific PDE) in the control of vaginal vascular smooth muscle, whereas only little is known on the rol

Soil biodiversity plays a key role in regulating the processes that underpin the delivery of ecosystem goods and services in terrestrial ecosystems. Agricultural intensification is known to change the diversity of individual groups of soil biota, but less is known about how intensification affects biodiversity of the soil food web as a whole, and whether or not these effects may be generalized acr

Aims Biogeographical evidence suggests a strong link between climate and patterns of species diversity, and climate change is known to cause range shifts. However, there is little understanding of how shifts affect community composition and we lack empirical evidence of recent impacts of climate change on the diversity of vertebrates. Using a long-term comprehensive dataset on bird abundance, we e

Background: Nursing practice has to contribute to evidence pointing out why there is a need for more nurse-designed randomized control trials (RCTs) focusing on evidence-based practice (EBP).How far this EBP has progressed in different health aspects is usually established by systematic reviews of RCTs. Nurse-led RCTs exist but no study has addressed the essentials of nursing care. Aim: The aim wa

A sudden unilateral loss or impairment of vestibular function causes vertigo, dizziness, and impaired postural function. In most occasions, everyday activities supported or not by vestibular rehabilitation programs will promote a compensation and the symptoms subside. As the compensatory process requires sensory input, matching performed motor activity, both motor learning of exercises and matchin