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VEGF synthesis is induced by prostacyclin and TGF-β in distal lung fibroblasts from COPD patients and control subjects : Implications for pulmonary vascular remodelling

Background and objective: Involvement of pulmonary vascular remodelling is a characteristic sign in COPD. Vascular mediators such as vascular endothelial growth factor (VEGF) and prostacyclin may regulate fibroblast activity. The objective was to study the synthesis of VEGF and interactions with prostacyclin and transforming growth factor (TGF)-β1 in lung fibroblasts from patients with COPD and he

Interactions affect hyphal growth and enzyme profiles in combinations of coniferous wood-decaying fungi of Agaricomycetes

Fomitopsis pinicola is a species of Polyporales frequently encountered in Nordic temperate and boreal forests. In nature, the fungus causes destructive brown rot in wood, colonizing tree trunks often occupied by other Basidiomycota species. We mimicked these species-species interactions by introducing F. pinicola to five white rot species, all common sapro-trophs of Norway spruce. Hyphal interacti

A Multidimensional Readiness Index for the Electrification of the Transportation System in China, Norway, and Sweden

The main objective of this paper is to develop a readiness index model that can serve as an analytical tool for exploring the achievements of the electrification of transportation systems. We have applied this readiness index model to evaluate the readiness positioning of China, Norway, and Sweden towards transportation electrification. We have chosen these three countries as they represent divers

How to Repurpose the University : A Resilience Lens on Sustainability Governance

Universities have an important role in moving society towards a more sustainable future. However, this will require us to repurpose universities, reorienting and refocusing the different university domains (education, research, campus, and outreach) towards sustainability. The governance structures and processes used to embed sustainability into the activities and operations of the institution are

Relations between changes in safety behavior, paranoid ideations, cognitive biases, and clinical characteristics of patients with a psychotic disorder over time

Background: Safety behaviors, both positive (maladaptive coping behavior) and negative (avoidance behavior), are used by people with paranoid delusions to avoid perceived threats. Safety behaviors contribute to the persistence of paranoid delusions by preventing disconfirmation of threat beliefs and may influence other psychiatric symptoms. This study investigated how changes in safety behaviors a

A preliminary validation of a dynamic speech motor assessment for Swedish-speaking children with childhood apraxia of speech

Objective: Children with speech sound disorders (SSDs) have difficulties affecting different levels of speech production. For treatment to be beneficial, it is important to differentiate between Childhood Apraxia of Speech (CAS)–a motor speech disorder with deficits in speech praxis–and other SSDs (nonCAS-SSD). We have previously developed a motor speech examination Dynamisk motorisk talbedömning

Development of an instant-mix probiotic beverage based on fermented quinoa with reduced phytate content

Quinoa (Chenopodium Quinoa Willd.), a South American grain, has great potential for innovation and development of improved food products because of its protein content and nutritional benefits. The study aimed to develop an instant-mix beverage based on fermented quinoa with reduced phytate content and viable lactic bacteria. Two different lactic fermentation processes were designed known as Ferme

Molecular assembly in block copolymer-surfactant nanoparticle dispersions : Information on molecular exchange and apparent solubility from high-resolution and PFG NMR

Internally structured block copolymer-surfactant particles are formed when the complex salts of ionic-neutral block copolymers neutralized by surfactant counterions are dispersed in aqueous media. Here, we report the1H NMR signal intensities and self-diffusion coefficients (D, from pulsed field gradient nuclear magnetic resonance, PFG NMR) of trimethyl alkylammonium surfac-tant ions and the poly(a

Dynamic band-shift signal in two-dimensional electronic spectroscopy : A case of bacterial reaction center

Optical nonlinear spectroscopies carry a high amount of information about the systems under investigation; however, as they report polarization signals, the resulting spectra are often congested and difficult to interpret. To recover the landscape of energy states and physical processes such as energy and electron transfer, a clear interpretation of the nonlinear signals is prerequisite. Here, we

Ground- And excited-state characteristics in photovoltaic polymer N2200

As a classical polymer acceptor material, N2200 has received extensive attention and research in the field of polymer solar cells (PSCs). However, the intrinsic properties of ground- and excited-states in N2200, which are critical for the application of N2200 in PSCs, remain poorly understood. In this work, the ground- and excited-state properties of N2200 solution and film were studied by steady-

Separation and not residency permit restores function in resignation syndrome : a retrospective cohort study

Despite poor treatment results, a family-oriented approach and the securing of residency have been deemed essential to recovery from resignation syndrome (RS). In a retrospective cohort study, we evaluated an alternative method involving environmental therapy, with patients separated from their parents, while actively abstaining from involving the asylum process in treatment. We examined medical r

Highly cross-linked polyethylene still outperforms conventional polyethylene in THA : 10-year RSA results

Background and purpose — Cup wear in total hip arthroplasty (THA) can be affected by different manufacturing processes of the polyethylene (PE). We report the long-term wear pattern differences, as well as early creep behavior, between conventional PE and highly cross-linked PE (HXLPE) liners, as measured with radiostereometry (RSA) up to 10 years. We also compare migration and clinical outcome of

Spectral Analysis for Signal Detection and Classification : Reducing Variance and Extracting Features

Spectral analysis encompasses several powerful signal processing methods. The papers in this thesis present methods for finding good spectral representations, and methods both for stationary and non-stationary signals are considered. Stationary methods can be used for real-time evaluation, analysing shorter segments of an incoming signal, while non-stationary methods can be used to analyse the ins

Chromosomal Instability and Genomic Amplification in Bone and Soft Tissue Tumours

Popular Abstract in Swedish De flesta cancerformer uppvisar förvärvade kromosomavvikelser. En del enklare avvikelser har visat sig förekomma enbart i en viss tumörform och kan därför användas som diagnostiska markörer. I de flesta fall föreligger emellertid ett komplext och ospecifikt avvikelsemönster, ibland med ett mycket kraftigt ökat antal kopior av vissa DNA-sekvenser, så kallad genamplifieri

Studies of Molecular and Cluster Fragmentation Using Synchrotron Radiation: Measurements and Models

A new spectrometer for studying photoinduced fragmentation has been designed and commissioned. The instrument produces a detailed view of the energy and angular emission of fragments, which in the case of small molecules can be related to their geometry at the moment of dissociation. The spectral profiles for single, double and triple ion coincidences are analyzed in terms of molecular alignment,

Suicide in Severe Depression: A Longitudinal Case-Control Study

Popular Abstract in Swedish Populärvetenskaplig sammanfattning Personer som är deprimerade löper större risk att begå självmord än de som har andra psykiska störningar. Studier har visat att cirka 6-15% av alla patienter med affektiv sjukdom begår självmord. Vidare har det visat sig att cirka hälften av alla människor som tar livet av sig har haft en depression. Man har därför sökt efter riskfaktSuicide in Severe Depression. A Longitudinal Case-Control Study. The present thesis is based on a case-control study of suicide victims with a severe depression/ melancholia. All patients admitted to the Department of Psychiatry 1956-1969 who received this diagnosis on a multiaxial schedule (1206 patients) were followed up in two sessions to 1984 and to 1998 concerning suicide and general mortali

Hysteresis and transient behavior in current-voltage measurements of hybrid-perovskite absorber solar cells

Hybrid organo-metal halide perovskites are an exciting new class of solar absorber materials and have exhibited a rapid increase in solar cell efficiencies throughout the past two years to over 17% in both meso-structured and thin-film device architectures. We observe slow transient effects causing hysteresis in the current-voltage characterization of these devices that can lead to an over- or und

Design for Desirability: An Innovation-Focused Research Collaboration between Academia and Industry

This paper outlines an innovation-focused design research collaboration that connects New Zealand design and manufacturing industry with advanced design thinking about design for desirability, a research area pursued at AFFECT - the Centre for Affective Design Research at Massey University in Wellington (NZ). Nowadays, it’s all about offering products that are desirable; products need to appeal to