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Subclass-switched anti-Spike IgG3 oligoclonal cocktails strongly enhance Fc-mediated opsonization
Cancer and autoimmunity: two sides of the same coin. Complement system proteins in the regulation of immune responses.
Factor H is an inhibitor of the complement system, essential for controlling the alternative pathway and also playing a crucial role in various cellular functions. In this thesis, we identified new intriguing functions of FH as a survival factor for primary human monocytes, promoting their differentiation into immunosuppressive macrophages. We showed that FH is expressed by human breast cancer cel
Reply to 'Blood pressure during moderate or maximal exercise : hardly two sides of the same coin'
Explaining environmental behavior with values, worldviews, and self-construal: Different sides of the same coin?
Values, worldviews, and self-construal are strong correlates of pro-environmental behavior. In this brief empirical note, we argue that these constructs overlap conceptually and share underlying dimensions. Using an international sample of 11,964 individuals, we demonstrate that values, worldviews, and self-construal can be reduced to two dimensions, self-focus and other-focus, capturing 67 % of v
Two Sides to the Same Coin: The Dual Life of Consultants in Employee and Employer Branding
Purpose: This research aims to gain an understanding on how consultants in small consultancies, who also hold internal human resource responsibilities, promote their organisation in employee and employer branding. Relevance: Due to the ambiguous consultancy profession and the high potential for individual influences on the corporate brand, branding becomes a very germane topic in our particular r
Bet on both sides of the coin to improve the organizational climate: The impact of congruent task and role clarity between leaders and staff
Four organizations at Stockholm-Arlanda airport are going through various organizational changes. They are preparing for present and future demands through structural changes, implementation of new technology, training, and other efficiency and capacity improving measures. The change processes will be followed during two years of which this paper presents the baseline measurement. The key factors
Among farmers and city people : coin use in early medieval Denmark c. 1000-1250
Two sides of the same coin?
Purpose: This study’s purpose is to study the long term effects of M&A and to examine whether stock price is the only determinant of post-merger performance or if operating performance can be used as an additional determinant. How underlying variables impact these measures are also part of this study´s purpose. Methodology: A quantitative approach is used where two event studies are conducte
The Other Side of the Coins - The Environmental Impact of Greenfield FDI in Sub-Saharan Africa´s Pollution-Intensive Industries and the Role of Governance
While foreign direct investments (FDI) are promoted as a vehicle for economic development their environmental consequences are less established. This study tests the hypotheses that 1) FDI led to environmental degradation in form of increased greenhouse gas emissions during Sub-Saharan Africa´s recent growth spurt but that 2) this impact was felt to a lesser extent in countries with a higher quali
Getting to know Initial Coin Offering Investors
Understanding the Initial Coin Offering Investor
Two sides of a coin: Analyzing benefits and limitations of payment for water ecosystem services in Lima´s water fund
Payment for water ecosystem services has been gaining attention in Latin America because of the direct response for environmental conservation through economic mechanisms. By connecting nature services with people who benefit from them, it creates a sustainable intervention for the ecosystem’s management while enhancing human well-being according to policy implementers. Nevertheless, these initiat
Carbon Coin: Exploring the Macroeconomic Implications of a Novel Climate Currency
Climate change poses a significant threat to global stability, with rising temperatures leading to severe environmental and economic impacts. In response, innovative policy mechanisms such as the Global Carbon Reward (GCR) have been designed to enhance the effectiveness of carbon pricing strategies. The foundational aspect of the GCR is a carbon reward, which acts as a financial incentive distribu
Two sides of the same green coin? A legal analysis of the concept of the (green) industrial competitiveness of the Union through the Net-Zero Industry Act
I den pågående kampen mot klimathotet har Europeiska unionen antagit en ledande roll för att fullfölja skiftet mot en grön ekonomi, bland annat genom att fokusera på att stärka konkurrenskraften avseende tillverkningen av netto-noll energiindustrin och säkra de nödvändiga råvarorna för denna omställning. För att möjliggöra detta presenterade den Europeiska kommissionen i mars 2023, i samband med pIn the global race against climate change, the answer of the European Union is the transition towards a green economy by focusing on strengthening the competitiveness of the net-zero technology industry and securing the necessary critical materials. To do so, the Union presented two legislative acts in the European Green Deal Industrial Plan in 2023, amongst which the Net-Zero Industry Act. While
False positive results in class-specific rheumatoid factor (RF) assays due to interaction between RF and Fc fragments of anti-immunoglobulin indicator reagents
Streptococcal beta protein has separate binding sites for human factor H and IgA-Fc.
EndoS and EndoS2 hydrolyze Fc-glycans on therapeutic antibodies with different glycoform selectivity and can be used for rapid quantification of high-mannose glycans.
Enzymes that affect glycoproteins of the human immune system, and thereby modulate defense responses, are abundant among bacterial pathogens. Two endoglycosidases from the human pathogen Streptococcus pyogenes, EndoS and EndoS2, have recently been shown to hydrolyze N-linked glycans of human IgG. However, detailed characterization and comparison of the hydrolyzing activities have not been performe
