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Purpose: To compare the performance of one-view digital breast tomosynthesis (1v-DBT) to that of three other protocols combining DBT and mammography (DM) for breast cancer detection. Materials and methods: Six radiologists, three experienced with 1v-DBT in screening, retrospectively reviewed 181 cases (76 malignant, 50 benign, 55 normal) in two sessions. First, they scored sequentially: 1v-DBT (me

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In the present study, two types of micro-pin–fin configurations were fabricated on silicon surfaces by a dry etching method, i.e., staggered pin fins (#1) and aligned pin fins with empty areas (#2). The micro-pin–fin surfaces were then further modified by depositing FeMn oxide nanoparticles (∼35 nm) electrostatically for 8 h and 16 h, respectively, namely #1-8h, #1-16h, #2-8h and #2-16h. Subcooled

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A new approach for the classification of patients with Sjogren's syndrome (SS) has been recently proposed. Although these new criteria substantially differ from the American European Consensus Group criteria, which have represented the gold standard for the last decade, when compared with each other the two sets show a high statistical degree of agreement. However, the fact that two different crit

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Postural orthostatic tachycardia syndrome (POTS) as conventionally defined is a chronic condition (typically >3 months duration) incorporating reproducible symptoms of orthostatic intolerance (including dizziness/lightheadedness, and near-syncope) in the absence of orthostatic hypotension (i.e., absence of a sustained systolic blood pressure drop >20mmHg with upright posture). 1-10 More recently

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Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3

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This study explores the use of manganese ore, iron-carbon particles (Fe-C), and gravel as anode fillers in electroactive constructed wetlands (ECWs) to treat wastewater containing pharmaceuticals and personal care products (PPCPs) including ciprofloxacin (CIP), ofloxacin (OFL), and naproxen (NPX), while also assessing bioelectricity production. Although the presence of PPCPs reduced pollutant remo

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Popular Abstract in Swedish Grupp B streptokocker (GBS; Streptococcus agalactiae) är den vanligaste orsaken till livs-hotande infektioner hos nyfödda barn. Enbart i USA orsakar GBS ~10 000 fall av meningit (hjärnhinneinflammation), pneumoni (lunginflammation) och sepsis (blodförgiftning) varje år. Infektionerna har hög dödlighet och en stor del av de barn som överlever infektionerna får bestående Streptococcus pyogenes (group A streptococcus) and the group B streptococcus (GBS) are two important human pathogens that cause different types of diseases and express different surface structures implicated in virulence. This thesis focuses on several surface proteins expressed by these pathogens, analyzing the biological function of these proteins and their ability to elicit protective immunity.

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The emergence of blockchain technology enables entrepreneurs to raise capital in an innovative way, by addressing a crowd of online investors without the need for an intermediary. This phenomenon is known as token sales, and it may have the potential to revolutionize entrepreneurial finance. However, information asymmetry is particularly severe in this context, and the need for entrepreneurs to se

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Angiogenesis provides growing tumors a source of nutrients and oxygen, and a route for metastatic dissemination. In recent years anti-angiogenic therapies that primarily target the vascular endothelial growth factor (VEGF) signaling cascade have entered the clinic. However in practice, these have encountered unexpected mechanisms of resistance in many solid tumors, highlighting the need for furthe

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In the existing securities market structure, a securities trade between two parties requires the involvement of several financial intermediaries ensuring the safety of the transaction. However, the complexity of today’s market structure in conjunction with the lack of interoperability between financial data infrastructures and the disalignment of business practices, are causing costs, risks and fr

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In nature, bacteria usually exist as mixed-species biofilms, where they engage in a range of synergistic and antagonistic interactions that increase their resistance to environmental challenges. Biofilms are a major cause of persistent infections, and dispersal from initial foci can cause new infections at distal sites thus warranting further investigation. Studies of development and spatial inter