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The nonobese diabetic (NOD) mouse spontaneously develops autoimmune-mediated diseases such as diabetes and Sjögren′s syndrome. To investigate whether NOD genes also promote autoimmune-mediatedarthritis we established a NOD strain with an MHC class II fragment containing the Aq class II gene predisposing for collagen induced arthritis (NOD.Q). However, this mouse was resistant to arthritis in contr

Eosinophils participate in the inflammatory response seen in allergy and helminthic infestation. Their release of granule-bound cationic proteins may play a role in these diseases. Therefore, we investigated mechanisms involved in the release of eosinophil cationic protein (ECP). Serum-opsonized zymosan was phagocytosed by eosinophils, and ECP was released into the phagosomes as judged by immunoel

Tumor-specific monoclonal antibodies (mAbs) offer several modes of tumor cell killing, from direct cytotoxic activity to indirect mechanisms employing the host immune system, particularly its innate branch. The latter effector functions seem to dominate among clinically approved anti-cancer mAbs and major efforts are being undertaken by both academia and the pharmaceutical industry with the aim to

Habitat w/Sirous Namazi Habitat Valbar kurs på BFA nivå/Optional BFA-level course Antal hp/Credits: 6 Lärare/Teacher: Sirous Namazi Tid/Time: 14–27.4, 10.00 – 16.00 .Undervisningsform/Form: Workshop, lectures, studio visits Språk/Language: Svenska och engelska/Swedish and English Antal studenter/Number of students: 8-10 Kursbeskrivning Habitat . Ett ord som anger en plats, en boplats, med gynnsamm

https://www.khm.lu.se/en/sites/khm.lu.se.en/files/habitat.docx - 2026-05-07

Neisseria gonorrhoeae is the etiological agent of gonorrhea, the second most common bacterial sexually transmitted infection worldwide. Reproductive sequelae of gonorrhea include infertility, ectopic pregnancy and chronic pelvic pain. Most antibiotics currently in clinical use have been rendered ineffective due to the rapid spread of antimicrobial resistance among gonococci. The developmental pipe

Hu11B6 is a monoclonal antibody that internalizes in cells expressing androgen receptor (AR)-regulated prostate-specific enzyme human kallikrein-related peptidase 2 (hK2; KLK2). In multiple rodent models, Actinium-225-labeled hu11B6-IgG1 ([225Ac]hu11B6-IgG1) has shown promising treatment efficacy. In the present study, we investigated options to enhance and optimize [225Ac]hu11B6 treatment. First,

On July 2018, for the first time in modern Mexican history, a leftist candidate won the presidential elections in Mexico. With large promises on the eradication of corruption and ending social injustice, Andrés Manuel López Obrador and his party secured both the presidency and both chambers of the Mexican Congress. This paper inquires into to what extent a president belonging to the political left

Medieval Europe was characterized by geopolitical disorder and territorial disunion. Around 1500 AD, as the modern era dawned, Europe comprised some 1,500 districts which were largely politically independent. Gradually, medium sized territories emerged around cores made up of cultural, economic, and political centres. The Lake Malar area in Sweden was such a territory; London, Paris, Berlin-Potsda

Drawing upon the perspective of the cultural studies of emotions, this article examines the reception of political satire and the re-contextualization of humour. More precisely, it investigates the multiplicity of tensions that come into play in the production, erasure, rediscovery, and reception in BelarusianInternet media of politically oriented Russian television humour mocking the Belarusian p

The aim of this article is to draw attention to the dangerous, indeed poisonous, nature of the current debates on immigration and multiculturalism in today’s ‘omniphobic’ Europe, plagued not only by a severe economic crisis, but also a more general normative crisis, a ‘crisis of values’ so to speak, which has been consistently overlooked or manipulated by politicians and academics alike, or reduce

In ESS, a 5 MW proton beam will hit a helium cooled tungsten target to generate neutrons by spallation. For the purpose of investigating various aspects of cooling with helium, an experimental system has been constructed at Lund University, Department of Energy Sciences. A helium flow of 3 g/s is circulated in a closed loop with pre-heater, cooler, filters and a test vessel. The vessel has windows