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Fetal middle cerebral to uterine artery pulsatility index ratios in normal and pre-eclamptic pregnancies

Objectives To calculate the normal range for the fetal middle cerebral artery (MCA)/uterine artery pulsatility index (PI) ratio in the third trimester of pregnancy and to assess its value, compared with that of the MCA/umbilical artery PI ratio, in predicting an unfavorable outcome of pregnancies complicated by pre-eclampsia. Methods Doppler blood flow velocimetry of the uterine and umbilical arte

Women´s Experience of a myocardial infarction

Popular Abstract in Swedish Hjärt- och kärlsjukdomar är idag den vanligaste dödsorsaken i stora delar av världen för både män och kvinnor. I Sverige är hjärtinfarkt den vanligaste dödsorsaken för kvinnor över 55 år och för män över 45 år. Det vill säga kvinnor drabbas cirka 10 år senare. Tidigare forskning har baserats i huvudsak på män varvid forskning på kvinnor med hjärt- och kärlsjukdomar har Background: Coronary heart disease (CHD) is the sleading cause of mortality in men and women in Western society. Few studies of CHD have been performed on women or with a focus on cardiac risk factors in women’s lives. Results from studies of men have been generalized to women, which may be inappropriate or even dangerous. Aim: The overall aim of this thesis was to describe women’s experience of a

Cardiometabolic Polygenic Risk Scores and Osteoarthritis Outcomes : A Mendelian Randomization Study Using Data From the Malmö Diet and Cancer Study and the UK Biobank

Objective: To investigate the causal role of cardiometabolic risk factors in osteoarthritis (OA) using associated genetic variants. Methods: We studied 27,691 adults from the Malmö Diet and Cancer Study (MDCS) and replicated novel findings among 376,435 adults from the UK Biobank. Trait-specific polygenic risk scores for low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol

HLA high-resolution typing by next-generation sequencing in Pandemrix-induced narcolepsy

The incidence of narcolepsy type 1 (NT1) increased in Sweden following the 2009-2010 mass-vaccination with the influenza Pandemrix-vaccine. NT1 has been associated with Human leukocyte antigen (HLA) DQB1*06:02 but full high-resolution HLA-typing of all loci in vaccine-induced NT1 remains to be done. Therefore, here we performed HLA typing by sequencing HLA-DRB3, DRB4, DRB5, DRB1, DQA1, DQB1, DPA1

Risk stratification in heart failure decompensation in the community : HEFESTOS score

Aims: Because evidence regarding risk stratification predicting prognosis of patients with heart failure (HF) decompensation attended in primary care is lacking, we developed and externally validated a model to forecast death/hospitalization during the first 30 days after an episode of decompensation. The predictive model is based on variables easily obtained in primary care settings. Methods and

Multicenter global early feasibility study to evaluate total endovascular arch repair using three-vessel inner branch stent-grafts for aneurysms and dissections

PURPOSE: To evaluate the outcomes of total endovascular aortic arch repair using three-vessel inner branch stent-grafts for aneurysms and chronic dissections.METHODS: We reviewed the clinical data and outcomes of consecutive patients treated by total endovascular aortic arch repair at eight academic centers using three-vessel inner branch stent-grafts (William Cook Europe, Bjaeverskov, Denmark) be

Revascularization of occluded renal artery stent grafts after complex endovascular aortic repair and its impact on renal function

Background: Acute occlusion of renal bridging stent grafts after fenestrated/branched endovascular aortic repair (F/B-EVAR) is an acknowledged complication with high morbidity that often results in chronic dialysis dependence. The feasibility and effect of timely or late (≥6 hours of ischemia) renal artery revascularization has not been adequately reported. Methods: We performed a retrospective, m

Molecular analyses of triple-negative breast cancer in the young and elderly

BACKGROUND: Breast cancer in young adults has been implicated with a worse outcome. Analyses of genomic traits associated with age have been heterogenous, likely because of an incomplete accounting for underlying molecular subtypes. We aimed to resolve whether triple-negative breast cancer (TNBC) in younger versus older patients represent similar or different molecular diseases in the context of g

Characteristics and Outcomes of Patients With Systemic Sclerosis (Scleroderma) Requiring Renal Replacement Therapy in Europe : Results From the ERA-EDTA Registry

Rationale & Objective: Data for outcomes of patients with end-stage renal disease (ESRD) secondary to systemic sclerosis (scleroderma) requiring renal replacement therapy (RRT) are limited. We examined the incidence and prevalence of ESRD due to scleroderma in Europe and the outcomes among these patients following initiation of RRT. Study Design: Registry study of incidence and prevalence and

Alzheimer's pathology targets distinct memory networks in the ageing brain

Alzheimer's disease researchers have been intrigued by the selective regional vulnerability of the brain to amyloid-β plaques and tau neurofibrillary tangles. Post-mortem studies indicate that in ageing and Alzheimer's disease tau tangles deposit early in the transentorhinal cortex, a region located in the anterior-temporal lobe that is critical for object memory. In contrast, amyloid-β pathology

Genetic Moderation of the Association of β-Amyloid With Cognition and MRI Brain Structure in Alzheimer Disease

Background and Objectives: There is considerable heterogeneity in the association between increasing β-amyloid (Aβ) pathology and early cognitive dysfunction in preclinical Alzheimer disease (AD). At this stage, some individuals show no signs of cognitive dysfunction, while others show clear signs of decline. The factors explaining this heterogeneity are particularly important for understanding pr

Sex differences in neuropsychiatric symptoms in Alzheimer’s disease dementia : a meta-analysis

Background: Neuropsychiatric symptoms (NPS) are common in individuals with Alzheimer’s disease (AD) dementia, but substantial heterogeneity exists in the manifestation of NPS. Sex differences may explain this clinical variability. We aimed to investigate the sex differences in the prevalence and severity of NPS in AD dementia. Methods: Literature searches were conducted in Embase, MEDLINE/PubMed,

Neuropsychological outcome after cardiac arrest : results from a sub-study of the targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest (TTM2) trial

Background: Cognitive impairment is common following out-of-hospital cardiac arrest (OHCA), but the nature of the impairment is poorly understood. Our objective was to describe cognitive impairment in OHCA survivors, with the hypothesis that OHCA survivors would perform significantly worse on neuropsychological tests of cognition than controls with acute myocardial infarction (MI). Another aim was

Coronary Artery Lesion Lipid Content and Plaque Burden in Diabetic and Nondiabetic Patients : PROSPECT II

BACKGROUND: Patients with diabetes have increased rates of major adverse cardiac events (MACEs). We hypothesized that this is explained by diabetes-associated differences in coronary plaque morphology and lipid content. METHODS: In PROSPECT II (Providing Regional Observations to Study Predictors of Events in the Coronary Tree), 898 patients with acute myocardial infarction with or without ST-segme

Racial and Ethnic Differences in the Association Between Classical Cardiovascular Risk Factors and Common Carotid Intima-Media Thickness : An Individual Participant Data Meta-Analysis

BACKGROUND: The major risk factors for atherosclerotic cardiovascular disease differ by race or ethnicity but have largely been defined using populations of European ancestry. Despite the rising prevalence of cardiovascular disease in Africa there are few related data from African populations. Therefore, we compared the association of established cardiovascular risk factors with carotid-intima med

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Gisa21 through oct. 30 2014

GISA21 Answer Count: 94 What did you like most in the course? Why?    What did you like most in the course? Why? The range of course topics. It seemed to cover all the fundamentals. I have been working in the GIS industry for over three years, but I found  the comprehensive review of the basics very useful. The freedom to try out different study methods and find which works best for me. The time s

https://www.nateko.lu.se/sv/sites/nateko.lu.se.sv/files/gisa21_through_oct._30_2014.pdf - 2026-05-28

Utredning-CEC

Postadress Centrum för miljö- och klimatvetenskap, Sölvegatan 37, 223 62 Lund. Besöksadress Ekologihuset, Sölvegatan 37, Lund Telefon (vxl) 046-222 00 00 E-post Henrik.Smith@biol.lu.se, Marianne.Hall@cec.lu.se Webbadress www.cec.lu.se Diarienummer STYR 2022/291 Datum 2022-11-14 Utredning av hur CEC:s verksamheter som rör koordinering av större forsknings- program och ämnesövergripande samverkanspl

https://www.naturvetenskap.lu.se/internt/sites/naturvetenskap.lu.se.internt/files/2022-12/Utredning-CEC.pdf - 2026-05-28

Prof-inst 17okt 2014

Professorsinstallation LUNDS UNIVERSITET | AULAN | 17 OKTOBER 2014 KL 17.00 Denna broschyr finns på installandis institutioner och kan också beställas från sektionen Kommunikation, tel 046-222 70 10, E-post info@kommunikation.lu.se. Broschyren finns även på www.lu.se/om-universitetet/akademiska-hogtider/professorsinstallationer Produktion Sektionen Kommunikation, Lunds universitet Foto Kennet Ruon

https://www.lu.se/sites/www.lu.se/files/prof-inst_17okt_2014.pdf - 2026-05-28