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Aims/hypothesis Most studies of diet in glucose intolerance and type 2 diabetes have focused on intakes of fat, carbohydrate, fibre, fruits and vegetables. Instead, we aimed to compare diets that were available during human evolution with more recently introduced ones. Methods Twenty-nine patients with ischaemic heart disease plus either glucose intolerance or type 2 diabetes were randomised to re
We develop and evaluate a large-scale dynamic vegetation model, TEM-LPJ, which considers interactions among water, light and nitrogen in simulating ecosystem function and structure. We parameterized the model for three plant functional types (PFTs): a temperate deciduous forest, a temperate coniferous forest, and a temperate C-3 grassland. Model parameters were determined using data from forest st
In this paper, nonlinear model predictive control (NMPC) is applied to the start-up of a combined-cycle power plant. An object-oriented first-principle model library expressed in the high-level language Modelica has been written for the plant and used to set up the simulation and optimization models. The NMPC optimization problems are both encoded, using a high-level notation, and solved in the op
Empirical software engineering research aims to generate prescriptive knowledge that can help software engineers improve their work and overcome their challenges, but deriving these insights from real-world problems can be challenging. In this paper, we promote design science as an effective way to produce and communicate prescriptive knowledge. We propose using a visual abstract template to commu
Aim: This study assessed whether a Swedish school-based exercise intervention programme could increase total physical activity. Methods: We followed up 228 children who started school in 1998-2000 seven years later, when they had reached a mean age of 14.8. The 152 children (59% boys) at the intervention school did 200 minutes of physical education per week during that period, and the 76 children
The incidence of type 1 diabetes (T1D) in Sweden is one of the highest in the world. However, the possibility of other types of diabetes must also be considered. In addition, individuals with T1D constitute a heterogeneous group. A precise classification of diabetes is a prerequisite for optimal outcome. For precise classification, knowledge on the distribution of genetic factors, biochemical mark
Classical homogenization theory based on the Hashin-Shtrikman coated ellipsoids is used to model the changes in the complex valued conductivity (or admittivity) of a lung during tidal breathing. Here, the lung is modeled as a two-phase composite material where the alveolar air-filling corresponds to the inclusion phase. The theory predicts a linear relationship between the real and the imaginary p
In the struggle to reach the national environmental policy objectives, environmental compensation has emerged as a possible policy tool that may contribute to achieving the objectives. In Sweden, environmental compensation is legally mandated mainly in cases of exploitation within Natura 2000 areas and nature reserves, which is handled through the Swedish Environmental Code. In contrast, regulator
Non-motor symptoms (NMS) of Parkinson's disease (PD) affect virtually every patient, yet they are under-recognized and under-treated. The NMS Questionnaire (NMSQuest) is a validated 30-item self-assessment instrument useful for NMS screening in clinic.
Vissa ungdomar som upplevt potentiellt traumatiserande händelser kan utveckla dissociationssymptom. Under gynnsamma förhållanden har människor en förmåga att integrera känslor, tankar, sinnesintryck och minnen av livshändelser in i en adaptiv och sammanhängande självbild och berättelse om självet. Dissociation i samband med trauma kan beskrivas som ett sammanbrott av denna förmåga. Dissociativa upAfter experiencing potentially traumatic events (PTEs) some adolescents develop pathological dissociation. Trauma-related dissociation can be described as a break-down of the individual’s capacity to integrate emotions, thoughts, sensations, and memories about traumatic or other events into an adaptive and coherent self-image and self-narrative. Dissociative experiences (DE) include experienced lo
Phosphatidylinositol 4,5-biphosphate (PIP2) is a membrane phospholipid that controls the activity of several proteins regulating cytoskeleton reorganization, cytokine gene expression, T cell survival, proliferation, and differentiation. Phosphatidylinositol 4-phosphate 5-kinases (PIP5Ks) are the main enzymes involved in PIP2 biosynthesis by phosphorylating phosphatidylinositol 4-monophosphate (PI4
Background Medullary thyroid carcinoma is an aggressive tumor and presents with significant morbidity and mortality and a high rate of lymph node metastases. The combination of total thyroidectomy and cervical lymphadenectomy is the essential treatment for those patients presenting with cervical lymph node metastases. Materials and methods A retrospective analysis of 117 patients operated for medu
Databases with information on malignant tumors are of great value for epidemiologic studies. From the Regional South Swedish Tumour Registry, which is of documented high quality, 24 patients out of 8008 with reported melanoma diagnosis 1973-2003 were reported as having multiple (>/=3) primary, invasive cutaneous malignant melanomas (CMM). Of the 76 tumours identified in these patients, 7 (9%) were
The global fashion industry causes severe environmental and social harm, underscoring the urgent need for a sustainability transition. Circular Business Models, such as Fashion Rental Services (FRS), represent a promising yet currently limited alternative with reduced environmental impacts. This study presents a case study of the fashion industry’s sustainability transition by exploring FRS in Swe
Previous findings on results of treatment of aggression in violent offenders show inconsistent results, and implementations of such treatments have demonstrated varying success with sometimes marginal gains in forensic settings. New methods, incorporating virtual reality as a tool for experiential learning, have been put forward yet require deepened investigations concerning both treatment content
Background: Cancer care for individuals with intellectual disabilities (ID) is challenging, with evidence of disparities, late diagnoses, and overlooked experiences of the individuals in question.Aim: To explore how individuals with concomitant ID and cancer experience the illness and navigate cancer care trajectories and everyday life from perspectives of themselves, their relatives and professio
