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Non-lethal infections are common in free-living animals and the associated sickness behaviours can impact crucial life-history trade-offs. However, little is known about the duration and extent of such sickness behaviours in free-living animals, and consequently how they affect life-history decisions. Here, free-living Eurasian blackbirds, Turdus merula, were immune-challenged with lipopolysacchar
The purpose of this study was to investigate the cause of death in subjects with α-synucleinopathies (ASs) and the confirmed presence of cardiac α-synuclein (α-syn), compared to non-AS disorders in a neuropathologically confirmed cohort. In total, 78 neuropathologically confirmed AS cases positive for cardiac α-syn were included in the study. Individuals with other neurocognitive diseases, having
When referring to non-present entities, speakers and signers can select from a range of different strategies to create expressions that range from extremely concise to highly elaborate. This design of referring expressions is based partly on the availability of contextual information that can aid addressee understanding. In the small signing community of Providence Island, signers' heavy reliance
Objective: To study occupational groups and occupational exposure in association with chronic obstructive respiratory diseases. Methods: In early 2000s, structured interviews on chronic respiratory diseases and measurements of lung function as well as fractional expiratory nitric oxide (FENO) were performed in adult random population samples of Finland, Sweden and Estonia. Occupations were categor
BACKGROUND: Individual randomized controlled trials (RCTs) of periprocedural anticoagulation with bivalirudin versus heparin during percutaneous coronary intervention (PCI) have reported conflicting results. Study-level meta-analyses lack granularity to adjust for confounders, explore heterogeneity, or identify subgroups that may particularly benefit or be harmed. OBJECTIVE: To overcome these limi
Protandry, the earlier arrival of males at the breeding grounds relative to females, is common in migratory birds. However, due to difficulties in following individual birds on migration, we still lack knowledge about the spatiotemporal origin of protandry during the annual cycle, impeding our understanding of the proximate drivers of this phenomenon. Here, we use full annual cycle tracking data o
Idiopathic pulmonary fibrosis (IPF) and lung cancer represent progressive lung diseases with a poor prognosis. IPF represents a risk factor for the development of lung cancer, and the incidence of lung cancer is increased in patients with IPF. Disease pathogenesis of IPF and lung cancer involves common genetic alterations, dysregulated pathways, and the emergence of hyperplastic and metaplastic ep
Demotivation (Dörnyei & Ushioda, 2011) and non-participation (Norton, 2001) characterise negative responses to classroom practice of a generally chronic nature. In this article, focus is directed to negativity that emerges within the context of a particular language developing activity, and which can be understood as a situated response to the activity's demands. In conceptualizing negative re
Innovation literature shows that the characteristics of a company's innovation processes determine their performance in different areas. In this study, we adopt a general conceptual model from innovation theory and apply it to packaging innovation. This helps identify and describe subprocesses in packaging innovation and how to measure their performance. It also links the packaging innovation proc
Local political leaders as well as international organizations have embraced participatory budgeting in response to problems of political exclusion and citizens’ dissatisfaction with representative democracy. This article provides a framework to highlight important aspects of the politics of participation. The framework allows scholars to explore how factors external to spaces of participation int
Crystalline magnesium stearate has been extensively used as an additive in pharmaceutical and other industries for decades. However, the lack of suitably large crystals has hindered the determination of the crystal structure and thereby a more fundamental understanding of the structure-functionality relationship. Presented here is the structure of magnesium stearate trihydrate as determined from X
BACKGROUND: Patients with oesophageal and gastric cancer have a low likelihood of being cured and suffer from a broad spectrum of symptoms and problems that negatively affect their quality-of-life (QOL). Although the majority (67-75%) of patients at the time of diagnosis suffer from an incurable disease, research has primarily focused on the pre- and postoperative phase among patients treated with
BACKGROUND: The Flow-Self Organizing Maps (FlowSOM) artificial intelligence (AI) program, available within the Bioconductor open-source R-project, allows for an unsupervised visualization and interpretation of multiparameter flow cytometry (MFC) data.METHODS: Applied to a reference merged file from 11 normal bone marrows (BM) analyzed with an MFC panel targeting erythropoiesis, FlowSOM allowed to
The design of port complexes is a process that requires considering geographical and economic features of the territory. It is necessary to aggregate the characteristics of coastal landscapes, seascapes, artificial elements, dangerous objects, etc. The experience of implementing such projects (for example, in Sabetta) suggests that all participants in the design process need highly precise geograp
Background: Communication is a key tool in the nursing profession. It is known that listeners are sensitive to the speaker's voice and interpret the speaker's intentions primarily from the non-verbal signal conveyed. Aim: To map and discuss the current state of knowledge and research evidence on professional voice use in health and nursing care. Design and Method: A scoping review adherent to the
Objectives: Sala Silver Mine in central Sweden was an important manufacturer of silver from at least the 16th till the early 20th century, with production peaking in the 16th, mid 17th and 19th centuries. The job opportunities offered by the mine attracted people to the area resulting in the development of a small township with an associated cemetery in the vicinity of the mining center. People af
Background: A healthy lifestyle has been shown to reduce the risk of coronary artery disease (CAD). The extent to which lifestyle influences the risk of CAD for people with pre-existing non-modifiable risk factors is less studied. We therefore examined the associations between a favorable lifestyle and incidence of CAD in population subgroups based on gender, age, educational level, and parental h
The increasing competition for water resources requires a better understanding of flows, fluxes, stocks, and the services and benefits related to water consumption. This paper explains how public domain Earth Observation data based on Moderate Resolution Imaging Spectroradiometer (MODIS), Second Generation Meteosat (MSG), Tropical Rainfall Measurement Mission (TRMM) and various altimeter measureme
Objective: The incidence of urinary bladder cancer (UBC) has increased in Sweden despite decreased smoking, indicating that other factors might be associated. The increased use of statin medication for elevated blood lipids might be one such influencing factor. The aim of the present study was to assess whether statins are afflicted with an increased incidence of UBC. Material and methods: Data fr
