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The adipokine resistin is suggested to be an important link between obesity and insulin resistance. In the present study, we assessed the impact of resistin as inflammatogenic cytokine in the setting of arthritis. In vitro experiments on human PBMC were performed to assess cytokine response and transcription pathways of resistin-induced inflammation. Proinflammatory properties of resistin were eva
This essay in literature science focuses on the representation and meaning of food in Swedish working class literature during two different eras in the 20th century. On the one hand the literature consists of five different authorships from 1925–1945 and on the other hand five authorships from 1985–2005. On the basis of culture materialist theory, the aim of the study is to investigate how and why
BACKGROUND: Suicide is a major global health problem, especially among youth. Suicide is known to be associated with a variety of social, economic, political and religious factors, vary across geographical and cultural regions. The current study aimed to investigate the effects of socioeconomic factors on suicide mortality rate across different regions in Iran.METHODS: The data on distribution of
Introduction: Endotoxemia developing during cardiosurgery as elevated endotoxin concentrations in patient's serum may prevail over 24 h after operation. A major reason is thought to be increased gut permeability resulting in endotoxin and bacterial leakage. In this study we aimed to measure endotoxin levels on samples obtained during and after cardiovascular procedures and compare them with clinic
ABSTRACT: We plan to conduct a case-control study to investigate whether exposure to nitrogen dioxide (NO2) increases the risk of stroke. In case-control studies, selective participation can lead to bias and loss of efficiency. A two-phase design can reduce bias and improve efficiency by combining information on the non-participating subjects with information from the participating subjects. In ou
The aims of the current study were to collect intestinal spirochaetes (genus Brachyspira) from farmed and wild mallards (Anas platyrhynchos) and to identify and classify those isolates that phenotypically resembled Brachyspira hyodysenteriae, an enteric pathogen of pigs. The isolation rate of Brachyspira spp. was high from both farmed (93%) and wild mallards (78%). In wild mallards, it appeared th
The purposes of the study are to compare point-of-care (POC) hemostatic devices in critically ill patients with routine laboratory tests and intensive care unit (ICU) outcome scoring assessments and to describe the time course of these variables in relation to mortality rate.
Debates around gender and sexuality currently inform important negotiations of citizenship and belonging in Canada. In this chapter, we broadly outline main areas of research in the social sciences for Canadianists from German-speaking countries. We focus on two separate but interrelated themes that have recently gained a particular salience in Canadian society and politics: 1) Gender and the oste
Analysis of the system of criminal procedure in Sweden in light of the proposal for the establishment of a European Public Prosecutor's Office.
The present study was devoted to investigate the effects of the metabotropic glutamate receptor(mGluR)5 antagonist [(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) and the mGluR1 antagonist, (3-ethyl-2-methyl-quinolin-6-yl)-(4-methoxy-cyclohexyl)-methanone methanesulfonate (EMQMCM), in animal studies indicative of antiparkinsonian-like activity such as haloperidol-induced catalepsy, hypoactivit
The objective was to compare volume blood flow (VBF) in the descending aorta (DAo) of gestational age and weight-matched growth restricted (GR) and normal (N) fetuses. A longitudinal study of 20 N was compared with 11 GR in two analyses matched for weight and gestation. DAo dimensions and flow velocity were measured simultaneously using a new technique combining an ultrasonic phase-locked echo-tra
Abstract in UndeterminedSwedish and French avoid placing focused constituents at the left periphery of sentences. This has previously been suggested to be due to phonological factors. Here, we develop this idea and argue that the reason for avoiding focus at the left edge in these languages is the existence of syntactically related prosodic prominences in the beginning of utterances. Initial focal
We tested the hypothesis that early brain recovery in hypoxic newborn piglets is improved by resuscitating with an O2 supply close to the minimum level required by the newborn piglet brain. Severely hypoxic 2-5-d-old anaesthetized piglets were randomly divided into three resuscitation groups: hypoxaemic (n = 8), 21% O2 (n = 8), and 100% O2 groups (n = 8). The hypoxaemic group was mechanically vent
Laser-induced autofluorescence spectra from humans were recorded in vivo at three different clinics in a study aimed at investigating the capability of this method to discriminate between malignant tumours and normal surrounding tissues. For the recordings a mobile trolley with the necessary equipment was constructed for use in an examination room or in an operating theatre environment. Laser ligh
Although the aviation industry has gone through great technological and commercial change in the last decades, basic civil aviation training has not changed accordingly. The consequences of the changes in civil aviation have rarely resulted in research programs in the field of basic civil aviation training and this phase, where future pilots gain their first sets of skills and knowledge, has long
Popular Abstract in Swedish Proteiner är livsnödvändiga och finns i alla celler. De flesta proteinerna katalysear kemiska reaktioner och kallas då enzymer. Enzymer och proteiner (äggviteämnen) är uppbyggda av aminosyror ihopkopplade till kedjor som kan vara olika långa. Det finns 20 stycken olika aminosyror. Man kan göra en liknelse med ett pärlhalsband tillverkat av 20 olika pärlor, varje pärla mFerrochelatase catalyses the terminal step in heme biosynthesis by inserting a ferrous ion into protoporphyrin IX. The reaction mechanism has in this thesis been studied by mainly crystallographic methods. The structure of ferrochelatase from Bacillus subtilis co-crystallized with N-methyl mesoporphyrin allowed for the first time a characterization of the active site of the enzyme. The structure
The main topic of this thesis is real-time quantification of relevant chromophores and light scattering elements in biological media. The presented methods and instrumentation are based on continuous wave (steady-state) optical measurements of (a) spatially-resolved diffuse reflectance from bulk media and (b) combined spatially-resolved and goniometric measurements of re-emitted light from thin sa
On the decision of the Swedish government, the Swedish National Road Administration (SNRA) has started a large-scale trial with Intelligent Speed Adaptation (ISA) in urban areas. One of the four test sites is the city of Lund. At the Department of Technology and Society, Lund University, research about ISA has been carried out since 1986 and the first field study was carried out in 1993. The ongoi
