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A recently observed Kπ = 1+ mode in deformed nuclei is studied microscopically. By calculating the energies, the B(M1)-values and the form-factors of inelastic electron scattering for 156Gd, we conclude that the relatively strong M1-strength observed at 3.075 MeV comes predominantly from the convection current of proton excitations in the Oh 1 2-orbit. We suggest a search for the M1-strength aroun
Introduction: Most neurodegenerative diseases, including Alzheimer's disease (AD) and multiple sclerosis (MS), feature abnormal tau phosphorylation (p-tau) in the brain. Prior immunostaining studies have shown p-tau accumulation in the AD retina, suggesting it may mirror brain tau pathology. Methods: We used mass spectrometry to quantify p-tau peptides in matched retinal and hippocampal samples fr
Rapid developments in animal-tracking technology have enabled major advances in the field of movement ecology, which seeks to understand the drivers and consequences of movement across scales, taxa, and ecosystems. The field has made ground-breaking discoveries, yet the majority of studies in movement ecology remain reliant on observational approaches. While important, observational studies are li
With their superficially shark-like appearance, the Mesozoic ichthyosaurs provide a classic illustration of major morphological adaptations in an ancestrally terrestrial tetrapod lineage following the invasion of marine habitats1, 2–3. Much of what is known about ichthyosaur soft tissues derives from specimens with body outlines4, 5–6. However, despite offering insights into aspects of biology tha
Homologous recombination (HR) is an important route for repairing DNA double-strand breaks (DSBs). The early stages of HR are well understood, but later stages remain mysterious. In this issue of Genes & Development, Hustedt and colleagues (pp. 1397–1415) reveal HROB as a new player in HR required for recruitment of the MCM8–9 complex, which is paralogous to the MCM2–7 replicative helicase. HR
BACKGROUND: Wolff-Parkinson-White (WPW) syndrome is a rare cardiac disorder that predispose to supraventricular arrhythmias. Prognosis is usually benign, yet there is an increased lifetime risk of sudden death. While typically sporadic, familial clustering has been reported. This study aimed to assess the risk of WPW, arrhythmias, and mortality among siblings of individuals with WPW.METHODS: This
Global health is a multidisciplinary field focused on improving health and achieving equity in health for all people worldwide. The COVID-19 pandemic left a profound and lasting impact on global mental health, triggering a surge in anxiety, depression, and stress-related disorders across all age groups and regions. As the world transitions into the post-COVID period, mental health has emerged as a
Breakthroughs in battery research are imperative to provide society with batteries that are safe and sustainable, have a high energy density, and have a long cycle life at low cost. Recent advances in research methodologies, the emergence of new market opportunities, and strategic funding schemes have allowed not only large, but also small companies, universities, and public research organizations
Objectives (1) To assess the risk of haematological malignancies in individuals with systemic sclerosis (SSc) compared with individuals without SSc; (2) to explore how the risk varies across groups stratified by sex and age; and (3) to determine when these malignancies present in relation to SSc diagnosis in a population-based setting. Methods We performed a nationwide cohort study using high-qual
Context. Ultra-hot Jupiters (UHJs) in close orbits around early-type stars provide natural laboratories for studying atmospheric escape and star-planet interactions under extreme irradiation and wind conditions. The near-ultraviolet (NUV) regime is particularly sensitive to extended upper atmospheric and magnetospheric structures. Aims. We investigate whether star-planet interactions in the WASP-1
This paper contributes to the understanding of power structures in civil society by the exploring organizational connections of leaders holding multiple top-level leadership positions in resource-rich civil society organizations (CSOs) in Sweden. Based on unique association network data among national level CSOs collected in 2018, we discuss possible explanations behind the observed clusters of or
This study contributes a novel perspective on how new venture teams navigate task re-allocation during the new venture development phase. It highlights the relevance of task re-allocation conflict, shows how “negative affect expectations” shape the unfolding of such conflicts, and demonstrates why acting out conflict and its associated negative affect can enable team members to make substantial ta
One year into Russia’s full-scale invasion of Ukraine, the West is in need for a diversified strategy when discussing the conflict with its partners. Due to historical experiences, non-European and non-Western countries look at the Russian aggression differently. Supporting Ukraine thus means learning how communicate the consequences of the ongoing invasion in a language that would take into accou
Meshless methods are numerical methods that have the advantage of high accuracy without the need of an explicitly described mesh topology. In this class of methods, the Radial Point Interpolation Method (RPIM) is a promising collocation method where the application of radial basis functions yields high interpolation accuracy for even strongly unstructured node distributions. For electromagnetic si
BACKGROUND AND PURPOSEMyelin water imaging (MWI) is a magnetic resonance imaging technique that quantifies myelin in-vivo. Although MWI has been extensively applied to study myelin-related diseases in groups, clinical use in individual patients is challenging mainly due to population heterogeneity. The purpose of this study was twofold: (1) create a normative brain myelin water atlas depicting the
Sea urchins can detect light and move in relation to luminous stimuli despite lacking eyes. They presumably detect light through photoreceptor cells distributed on their body surface. However, there is currently no mechanistic explanation of how these animals can process light to detect visual stimuli and produce oriented movement. Here, we present a model of decentralized vision in echinoderms th
Spatial orientation is a prerequisite for most behaviors. In insects, the underlying neural computations take place in the central complex (CX), the brain’s navigational center. In this region different streams of sensory information converge to enable context-dependent navigational decisions. Accordingly, a variety of CX input neurons deliver information about different navigation-relevant cues.
We coordinate interconnected agents where the control input of eachagent is limited by the control input of others. In that sense, the sys-tems have to share a limited resource over a network. Such problems canarise in different areas and it is here motivated by a district heating ex-ample. When the shared resource is insufficient for the combined needof all systems, the resource will have to be s
RNA-directed transposon silencing operates in the mammalian soma and germline to safeguard genomic integrity. The piRNA pathway and the HUSH complex identify active transposons through recognition of their nascent transcripts, but mechanistic understanding of how these distinct pathways evolved is lacking. TASOR is an essential component of the HUSH complex. TASOR's DUF3715 domain adopts a pseudo-
