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Denna avhandling handlar om hur arkitektur producerar normer genom hållbar stadsutveckling, från formulering av visioner och strategier till materialisering och design. Den handlar också om arkitekturens potentiella roll i att omförhandla och utmana den normativt utstakade vägen framåt, till förmån för alternativa förhållningssätt. Hållbar stadsutveckling beskrivs i avhandlingen som en typologi avArchitecture, planning and urban design are some of the professional practices that contribute to the spatial aspects of societal organization and enable everyday life to run smoothly. The urgent and intertwined challenges of climate change and social injustice have introduced new dimensions to these tasks, frequently framed as working towards ‘sustainable development.’ In this doctoral thesis, I

Duplication of PLP1 (proteolipid protein gene 1) and the subsequent overexpression of the myelin protein PLP (also known as DM20) in oligodendrocytes is the most frequent cause of Pelizaeus-Merzbacher disease (PMD), a fatal leukodystrophy without therapeutic options. PLP binds cholesterol and is contained within membrane lipid raft microdomains. Cholesterol availability is the rate-limiting factor

The disparity between increased lifespan and healthy aging, marked by prevalent “inflammaging”, highlights the global challenge in care of older persons. This study explored the anti-inflammatory effects of Lactiplantibacillus plantarum HEAL9 (LpHEAL9), alone or combined with berries, on older volunteers with chronic low-grade inflammation (LGI). It was a randomized, double-blind, placebo-controll

Background Gender discrimination of women is often emphasized in work contexts, whereas less focus is on how men are discriminated against in social relationships. Gender discrimination in decisions of family relations, is essential to study as the contact between parent and child is commonly viewed as the most important relationship in people’s life, as well as being the most important aspect of

The tumor microenvironment (TME) is composed of various cellular components such as tumor cells, stromal cells including fibroblasts, adipocytes, mast cells, lymphatic vascular cells and infiltrating immune cells, macrophages, dendritic cells and lymphocytes. The intricate interplay between these cells influences tumor growth, metastasis and therapy failure. Significant advancements in breast canc

For a century, transport systems have been governed by masculine norms, constraining both women and men within the conditions and mobility behaviour it has established. This article explores the potential implications of adopting feminine norms for mobility and transport systems. Current masculine mobility norms are contested by investigating what including a feminine mobility concept would entail

The transition towards a circular economy (CE)relies on a supporting policy framework. TheEU is currently recognised as a global leader inclimate action and has adopted a comprehensivepolicy package to reach the objectives set outin its Circular Economy Action Plan. This paperexamines current and planned CE policies, theirkey impact on industries – with a focus on es-tablished manufacturing indust

Hållbarhet och hållbar mobilitet har blivit viktiga mål i national politik och policy. Cykling har dock inte kunnat dra nytta av detta. Om man betraktar cyklingens betydelse under de senaste decennierna, och dess förväntade betydelse i framtiden, finns emellertid få anledningar till optimism, åtminstone inte på nationell och övergripande nivå; cykeln befinner sig fortfarande i skuggan av bilen. DeSustainability and sustainable mobility have become important political goals and have left their mark as important discourses in national policies and programs. Against expectations, cycling has barely benefited from this. Looking back over the shoulder at the significance of cycling over the last few decades and looking forward to suggested implications in the future give no reason for joy, at l

IntroductionThis paper focuses on retailing in vulnerable areas, which are commonly associated with segregation,crime, violence, and unsafety (Swedish Police Authority, 2023; Gerell et al., 2021). Less attention isusually paid to the conditions of retailing in these neighbourhoods. A well-functioning grocery storecan be a decisive factor in the attractiveness of an area and in making it safe. At t

Microplastics (MP) have emerged as significant global pollutants, garnering considerable attention from both the scientific community and the public. The significance of microplastic research lies in its capacity to inform effective pollution control strategies and mitigate associated environmental and health risks. The review illuminated the complexities and challenges inherent in analyzing micro

Timely light exposure is a vital aspect to achieve better sleep and well-being. As there are risks with a disturbed circadian rhythm and benefits with light settings that stimulate the rhythm, the circadian effective light, circadian stimulus (CS), for radiographers was examined. Aim: The aim of the study was to compare radiographers’ light environment on the workstations, at a university hospital

On December 9, 2016, South Korea's National Assembly voted to impeach the country's president, Park Geun-hye, over abuse of power among other charges. Three months later, the Constitutional Court upheld the impeachment and she was dismissed from office-the first South Korean president to be removed this way. New elections were called. Park was then made the subject of a criminal investigation and

A lack of empathy, and particularly its affective components, is a core symptom of behavioural variant frontotemporal dementia (bvFTD). Visual exposure to images of a needle pricking a hand (pain condition) and Q-tips touching a hand (control condition) is an established functional magnetic resonance imaging (fMRI) paradigm used to investigate empathy for pain (EFP; pain condition minus control co

Real wages are a convenient, useful, and powerful way to learn how life was like in the past. In this chapter we start by reviewing the methodology behind real wage estimations and their history. Then we look at the how real wages have contributed to shedding light on major issues in economic history such as the onset of modern economic growth, the Great Divergence, and colonialism in the Americas

Targeted molecular dynamics was used to examine the mechanism of WPD loop closure in PTP1B, which is essential for the activity of the enzyme. Two important regions are identified: the R-loop (residues 113-118), which assists in substrate binding, and the S-loop (residues 198-209), which undergoes a conformational change that appears to be vital for the movement of the WPD loop. The S-loop is adja

This configurative review explores how nurturing and enacting a community-oriented praxis (COP) in teacher education can enhance teacher candidates’ preparedness for teaching roles whilst addressing some broader educational and societal concerns. Here, CoP is defined as practices that consider, connect with, and draw on local community strengths, needs, and aspirations for the good of individuals,

Importance: Studies have suggested an increased risk of psychiatric disorders and suicidal behavior among individuals who have undergone tonsillectomy. However, little is known about stress-related disorders. Objective: To investigate whether surgical removal of tonsils or adenoids is associated with a subsequent risk of stress-related disorders. Design, Setting, and Participants: This cohort stud

Background: In addition to peripheral neuropathy of various kinds, diabetes can also cause central neuropathy, which among other things can manifest itself as premature cognitive dysfunction, often linked to vascular dysfunction. Although the link between diabetes and cognitive dysfunction was discovered more than 100 years ago and has important clinical implications, this diabetes complication re