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Context. The HD 108236 system was first announced with the detection of four small planets based on TESS data. Shortly after, the transit of an additional planet with a period of 29.54 d was serendipitously detected by CHEOPS. In this way, HD 108236 (V = 9.2) became one of the brightest stars known to host five small transiting planets (Rp < 3 Ro˙). Aims. We characterize the planetary system by us

BACKGROUND: The Xpert MTB/RIF Ultra (Xpert-Ultra) assay provides timely results with good sensitivity and acceptable specificity with stool specimens in children for bacteriological confirmation of tuberculosis (TB). This study aims to optimize the Simple One-Step (SOS) stool processing method for testing stool specimens using the Xpert-Ultra in children and adults in selected health facilities in

BackgroundThe relationships between North Atlantic and North Pacific faunas through times have been controlled by the variation of hydrographic circumstances in the intervening Arctic Ocean and Bering Strait. We address the history of trans-Arctic connections in a clade of amphi-boreal pelagic fishes using genealogical information from mitochondrial DNA sequence data. The Pacific and Atlantic herr

Objective: The elderly are an increasing group and large consumers of care in Sweden. Development of mobile information technology shows promising results of interventions for prevention and treatment of chronic diseases. Exploring the elderly patients’ beliefs, attitudes, experiences and expectations of e-health services helps us understand the factors that influence adherence to such tools in pr

BACKGROUND: Hip fractures are a common problem in the ageing population. Hip arthroplasty is the common treatment option for displaced intracapsular neck of femur fractures. Even though hip replacements are successful in restoring mobility, reducing pain and diminishing loss of health-related quality of life, the potential impact of a hip fracture on life expectancy as well as the postoperative mo

Background: Stress myocardial perfusion scintigraphy (MPS) is widely regarded as a useful imaging modality for diagnosing patients with suspected ischemic heart disease. Current European guidelines recommend stress study to be performed first since rest study can be omitted if stress study is interpreted as normal. Thus, a rest study should only be performed in patients with equivocal or abnormal

Background: The use of analgesic antipyretics (ANAP) in children have long been a matter of controversy. Data on their practical use on an individual level has, however, been scarce. There are indications of possible effects on glucose homeostasis and immune function related to the use of ANAP. The aim of this study was to analyze patterns of analgesic antipyretic use across the clinical centers o

Brain structure and function are tightly correlated across all animals. While these relations are ultimately manifestations of differently wired neurons, many changes in neural circuit architecture lead to larger-scale alterations visible already at the level of brain regions. Locating such differences has served as a beacon for identifying brain areas that are strongly associated with the ecologi

Recent studies have indicated a decline in sperm number in the western world during the past 50 years, sperm concentration changing from 113 to 66 millions per mL. Furthermore, significant geographical differences in male reproductive function have been observed. In Finland, the sperm concentration was found to be substantially higher than in Denmark. In parallel, the incidence of testicular cance

A radioactive variant of the cytostatic agent cis-dichlorodiammineplatinum(II), cisplatin, was synthesised from 191PtCl4. The 191Pt-cisplatin was found to be a sterile product of high radionuclide, radiochemical and chemical purity. The pharmacokinetics of platinum in tumour tissue and organs at risk of fourteen patients undergoing treatment with cisplatin were studied by exchanging a small fracti

Pathogenic bacteria often produce potent proteases capable of destroying host tissue thereby providing the bacteria with tools for spreading and nutrient access. This thesis describes how group A, C and G streptococci can acquire surface bound protease activity through an alternative mechanism, namely by binding and activation of the human protease precursor plasminogen. Group A streptococci of c

The autumn gum moth, Mnesampela privata, utilizes several species of Eucalyptus planted outside regions of endemism within Australia. We investigated whether foliar monoterpene composition influenced oviposition in the field on the natural primary host (E. globulus) and a novel host (E. rubida), both characterized by nonstructural epicuticular waxes. In the laboratory, oviposition preferences of f

Liquid-liquid phase separation occurs in young mammalian eye lenses and in concentrated solutions of isolated eye lens proteins, and has been linked to some forms of cataract. Here we study theoretically the protein compositions and cloud temperatures of two separated equilibrium phases that form out of concentrated mixtures of model proteins, chosen to have properties similar to those which repro

This article analyses the path dependence of European copyright. It shows how copyright is legally constructed, is harmonised through international treaties and European regulatory efforts in terms of InfoSoc Directive and the IPRED, and is also affected by the Data Retention Directive and the Telecommunications Reform package. Furthermore, the “secretly” negotiated ACTA agreement is discussed as

Popular Abstract in Swedish De nu gällande trafikpolitiska principerna för kostnadsansvaret lades fast i 1988 års trafikpolitiska beslut (Regeringens proposition 1987/88:50 om trafikpolitiken inför 1990-talet). Utgångspunkten för kostnadsansvaret är trafikavgifter på samhällsekonomiska villkor med syfte att ge rätt beteendesignaler på transportområdet. Från denna utgångspunkt har kostnadsansvaret Transport is a key factor for economic growth. It has enabled both the economic scale of production and an increase in competition. No one can question this role of transportation. There is, however, a back-side to the coin: the environmental challenge. Present trends show that transportation is not compatible with sustainable development. The need to internalise the external effects from trans-po

Coordination of policies embracing biomass use has been called for in order to speed up progress towards the European Union renewable energy and climate change goals. Policy coordination and coherence is also required if the many complex and diverse issues constraining sustainable bioenergy development are to be addressed. To contribute to meeting such needs this doctoral thesis provides insights

Popular Abstract in Swedish Våtmarker är en naturtyp som man finner i övergångszoner mellan land och vatten. Idag talas det mycket om våtmarkers positiva natur- och miljövärden i avrinningsområden i det moderna jordbrukslandskapet. Våtmarker ger omväxling i landskapet och är viktiga biotoper för växter och djur. I våtmarker ansamlas mycket dött växtmaterial och tillsammans med en god tillgång på vIn this thesis, I have studied nitrogen turnover processes in watermeadows. A watermeadow is a wetland where water infiltrates through the soil of a grassland field. It is hypothesized that infiltration of water through the soil matrix promotes nutrient transformations compared to surface flow of water, by increasing the contact between water, nutrients, soil organic matter and bacteria. I have st

Popular Abstract in Swedish Jag genomför i min avhandling en etisk analys av texter av tre samtida feministiska teologer: Chung Hyun Kyung, Sydkorea, Katie G. Cannon, USA och Mary C. Grey, Storbritannien. Genom valet av dessa tre teologer, verksamma i olika kulturella kontexter, iscensätter jag vad som kan kallas ett flerkulturellt samtal, där jag själv ingår som en part. I samtalet framträder bl In this thesis in ethics I study and analyze feminist theological texts from 1988–1997 by Katie G. Cannon, Chung Hyun Kyung and Mary C. Grey. A culturally diverse conversation is constructed, in which womanist issues, Asian women’s concerns, and feminist critique of the Western European philosophical and theological traditions are brought into dialogue with a Swedish context. The theories used are

COPHES/DEMOCOPHES has its origins in the European Environment and Health Action Plan of 2004 to "develop a coherent approach on human biomonitoring (HBM) in Europe". Within this twin-project it was targeted to collect specimens from 120 mother-child-pairs in each of the 17 participating European countries. These specimens were investigated for six biomarkers (mercury in hair; creatinine, cotinine,

Although an important biomarker in breast cancer, Ki67 lacks scoring standardization, which has limited its clinical use. Our previous study found variability when laboratories used their own scoring methods on centrally stained tissue microarray slides. In this current study, 16 laboratories from eight countries calibrated to a specific Ki67 scoring method and then scored 50 centrally MIB-1 stain