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Renaissance 1.5

Projektet Renässans 1.5 utgår ifrån det faktum att det i den traditionella produktutvecklingsprocessen normalt krävs flera iterationer i processens olika faser innan man kan nå en acceptabel kompromiss mellan estetiska krav och konstruktions- och tillverkningskrav. Den snabba utvecklingen inom optimeringsteknik och kunskapsbaserad konstruktion gör det möjligt att integrera ett datorbaserat formgivThe Renaissance 1.5 project was based on the observation that in traditional product development, several iterations are needed to obtain a compromise between engineering, manufacturing constraints and aesthetics. The rapid advances in optimisation methods and in knowledge-based engineering (KBE) make it possible to integrate engineering and manufacturing constraints in a computer-based industrial

To reduce a ribonucleotide – Radical solutions in enzymology in form and function

Popular Abstract in Swedish För att levande celler ska kunna föröka sig behöver förr eller senare celldelning ske. Detta är en process där en ny cell skapas utifrån den information som finnas lagrad i ursprungscellen. Denna typ av information lagras i cellens DNA. En stor del av DNA:t är ritningar för hur cellens arbetarmolekyler, proteinerna, ska byggas men DNA:t innehåller även information för rIt has been more than 50 years since the enzyme system ribonucleotide reductase (RNR), catalysing the reduction of ribonucleotides to deoxyribonucleotides, was first discovered. RNR was also the first time that radical chemistry was revealed in an enzyme. RNRs carry out a key step in the de novo synthesis of building blocks for DNA and have been found in almost all known organisms. Within this th

APOE genotype and extent of bleeding and outcome in lobar intracerebral haemorrhage: a genetic association study

Background Carriers of APOE epsilon 2 and epsilon 4 have an increased risk of intracerebral haemorrhage (ICH) in lobar regions, presumably because of the effects of these gene variants on risk of cerebral amyloid angiopathy. We aimed to assess whether these variants also associate with severity of ICH, in terms of haematoma volume at presentation and subsequent outcome. Methods We investigated the

Etik och känslor : en empirisk studie av skuld- och medkänslor hos gymnasieelever – en prövning av Ortonys teori

Popular Abstract in SwedishEn del av Ortonys teorimodell angående den kognitiva strukturen hos emotioner testades på svenska gymnasieelever. Den del av teorin som användes i föreliggande studie handlade om de emotioner som tillskrivs den som utfört s.k. orätta handlingar. De eventuella känslor som man får när man utfört en orätt handling kallar Ortony för "self reproach" emotioner. Detta begrepp sThe purpose of this study was to test parts of Ortony's theoretical model relating to the cognitive structure of emotions in Swedish upper secondary school students. That part of the model, which was appropriate for the present study, deals with emotions attributed to the person who has perpetrated what is referred to as blameworthy actions. Ortony calls the possible emotions that you experience w

The Politics of Social Networks : Interpersonal Trust and Institutional Change in Post-Communist East Germany

Popular Abstract in Swedish Hur förändras organisationer? Medan statsvetenskaplig ny-institutionell teori är mer inriktad på att förklara varför institutioner är seglivade och svåra att förändra, så antar ekonomisk organisationsteori att organisationer relativt enkelt anpassar sig till omgivningens krav. Det sociala nätverks-perspektivet fokuserar de strukturer av samarbete och tillit som utvecklaNew institutionalist approaches are inherently weak at accounting for institutional change. In this book, social network analysis is proposed as a key to institutional change. The social network perspective focuses emergent patterns of interpersonal interaction and the resulting ties of interpersonal trust. As a complement and contrast to both March and Olsen’s influential new institutionalist "lo

Inkomst av näringsfastighet i enskild näringsverksamhet - arbetsinkomst eller kapitalinkomst?

Since the tax reform of 1990 the Swedish tax system separates earned income and capital income. On earned income such as "income from business" taxes and fees leads to a total margin tax burden that vary between 45 and 75 %. This margin effect can be compared to the 30 % proportional income tax on capital income. The allocation of income to earned income or capital income is therefore an important

Modelling the Variability of Bending Strength in Structural Timber - Length and Load Configuration Effects

Popular Abstract in Swedish Hållfastheten hos en balk av konstruktionsvirke är beroende av balkens spännvidd och typ av belastning. En längre balk har en lägre hållfasthet än en kort balk på samma sätt som en balk med konstant moment har lägre hållfasthet än en balk belastad med en punktlast. Orsaken till denna längd- och lastberoende bärförmåga är variationen i hållfasthet längs med en balk. VariThe load carrying capacity of a beam of structural timber is dependent both on the span of the beam and the type of loading. The longer the beam and the more uniform the moment distribution, the lower the load carrying capacity. This phenomenon is due to the variability of material properties within a piece of timber. This variability is, in turn, due to the presence of knots, the slope of grain a

Financing of Small and Cottage Industries in Bangladesh by Islamic Banks: An Institutional-Network Approach.

Popular Abstract in Swedish I denna studie utvecklas olika begrepp och samband mellan dessa begrepp (en teoretisk referensram) för att beskriva och förklara relationer mellan långivare och låntagare i landsbygdsbaserade små företag och de förhållanden i omgivningen som påverkar dessa relationer. Referensramen tillämpas på Bangladesh betonar särskilt den roll som islamska banker har. Teorier från iThis study is characterized by its development of an analytical framework for describing and explaining the lender-borrower financing relationships of rural-based small and cottage industries by including contextual conditions. It applies this framework to the socio- environmental conditions of Bangladesh with special emphasis on the role of Islamic banks. A theoretical framework based on institu

The threat from non indigenous species - ecosystem vulnerability, global distribution and co-occurrence with other major threats

Popular Abstract in Swedish Främmande arter är sådana som introducerats med människans hjälp till områden de inte kan sprida sig till på egen hand. Om en introducerad art är framgångsrik och lyckas etablera och sprida sig i mottagarregionen kan den påverka de inhemska arterna genom predation, konkurrens, hybridisering, parasitism och förändring av habitat. Eftersom arterna i mottagarområdet inte hWe live in a globalised world where people and goods travel large distances. Various species are brought along on these journeys, intentionally or as hitchhikers. Some of these species establish populations in regions to which they could not have spread without human assistance, and where they are considered to be non indigenous species (NIS). These species can affect the ecosystem in the recipien

Population and Community Dynamics in Variable Environments

Popular Abstract in Swedish Alla naturliga djur- eller växt- populationer varierar i tid och rum. Om man exempelvis räknar antalet individer av en viss art som befinner sig på ett visst ställe varje år, finner man att det antalet varierar från år till år. Varje år föds ett antal nya individer samtidigt som vissa dör (här bortser jag från de individer som eventuellt flyttar ut eller in). Antalet inAll natural populations fluctuate in space and time. These fluctuations are a result of internal dynamic processes, and of a variable environment. To understand how and why population fluctuate, one has to understand the nature of the internal demographic processes as well as how a variable environment affects these processes and how they act in concert to generate population fluctuations. This th

Continuum Mechanics Modelling of Corrugated Board

Popular Abstract in Swedish Wellpapp är ett populärt material i förpackningar för transport och lagring av konsumentvaror. Den viktigaste anledningen till dess popularitet är materialets höga styvhet och styrka, i förhållande till vikt och kostnad. Ingenjörsmässig användning av wellpapp kompliceras av många faktorer. En väsentlig nackdel är materialets känslighet för fuktpåverkan, vilken dessutom The storage of compressive loaded boxes in an environment with naturally varying humidity is a practical issue in corrugated board employment. Time dependent variables such as moisture content, strain fields, stress fields and material strength play important roles for the time to failure. Supplementary, the stochastic nature of material and moisture load is obstructing the prediction of a reliabl

Cyclin E overexpression and associated events in human breast cancer

Unrestrained proliferation is a hallmark of cancer and genetic defects within G1/S-phase regulation and the pRb pathway occur frequently. Proliferation control can be circumvented either by excess cyclin D1 or cyclin E, alterations that can define two alternative tumour biologic pathways in breast cancer. By overexpressing cyclin E in a cell line model system we demonstrate that the capacity of ce

COL1A1 Sp1 polymorphism predicts perimenopausal and early postmenopausal spinal bone loss

Genetic factors play an important role in the pathogenesis of osteoporosis but the genes that determine susceptibility to poor bone health are defined incompletely. Previous work has shown that a polymorphism that affects an Spl binding site in the COLIA1 gene is associated with reduced bone mineral density (BMD) and an increased risk of osteoporotic fracture in several populations. Data from cros

A critical review on the application of the National Sanitation Foundation Water Quality Index

Many studies have employed the National Sanitation Foundation Water Quality Index (NSFWQI) with non-original rather than originally defined parameters of the model, particularly when incorporating fecal coliform (FC), total solids, and total phosphates as inputs. For this reason, this study aimed to perform a critical review on the application of the NSFWQI to explore the amount of change that can

Future Circular Collider : Vol. 3 The Hadron Collider (FCC-hh)

Particle physics has arrived at an important moment of its history. The discovery of the Higgs boson, with a mass of 125 GeV, completes the matrix of particles and interactions that has constituted the “Standard Model” for several decades. This model is a consistent and predictive theory, which has so far proven successful at describing all phenomena accessible to collider experiments. However, se

Avtal-om-ersattning-vid-arbetsskada-i-statlig-forvaltning

Om ersättning vid arbetsskada PSA AFA Försäkring ger trygghet och ekonomiskt stöd vid sjukdom, arbetsskada, arbetsbrist och dödsfall. Våra försäkringar är bestämda i kollektivavtal mellan arbetsmarknadens parter. Vi försäkrar drygt fyra miljoner människor i privat näringsliv, kommuner, landsting och regioner och förvaltar cirka 200 miljarder kronor. En viktig del av vår verksamhet är att stödja fo

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/avtal-om-ersattning-vid-arbetsskada-i-statlig-forvaltning.pdf - 2026-05-30

Lighting Control Systems to Save Energy in the non-Residential Sector : State-of-the-art, Field Studies, and Simulations

This thesis examines the energy-saving potential for lighting when using traditional indoor LCSs in non-residential buildings. In the study, an overarching theoretical framework is used that distinguishes between energy efficiency and energy saving, as well as between energy use for lighting and functional illumination. This framework also includes the hypothesis that user acceptance is a determin

Medial temporal lobe Tau-Neurodegeneration mismatch from MRI and plasma biomarkers identifies vulnerable and resilient phenotypes with AD

BACKGROUND: The heterogeneity of Alzheimer's disease (AD) and lack of well-validated markers of non-AD factors (e.g. TDP-43) present a substantial challenge for therapeutics. Our prior work showed discordance between tau (T) and neurodegeneration (N) identified non-AD factors in AD through multi-modality imaging. Here we tried a simplified approach using plasma ptau217 and medial temporal lobe (MT

Medial temporal lobe Tau-Neurodegeneration mismatch from MRI and plasma biomarkers identifies vulnerable and resilient phenotypes with AD

BACKGROUND: The heterogeneity of Alzheimer's disease (AD) and lack of well-validated markers of non-AD factors (e.g. TDP-43) present a substantial challenge for therapeutics. Our prior work showed discordance between tau (T) and neurodegeneration (N) identified non-AD factors in AD through multi-modality imaging. Here we tried a simplified approach using plasma ptau217 and medial temporal lobe (MT

Publication in experimental cell research 0

doi:10.1016/j.yexcr.2004.04.037 www.elsevier.com/locate/yexcr Experimental Cell Research 298 (2004) 611–623 Dynamics of transgene expression in a neural stem cell line transduced with lentiviral vectors incorporating the cHS4 insulator Johan Jakobsson, Nina Rosenqvist, Lachlan Thompson, Perrine Barraud, and Cecilia Lundberg* Wallenberg Neuroscience Center, Department of Physiological Sciences, Lun

https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/publication_in_experimental_cell_research_0.pdf - 2026-05-30