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Building predictive unbound brain-to-plasma concentration ratio (Kp,uu,brain) models

Popular science summary: Predictive model for unbound brain-to-plasma concentration ratio Blood-brain barrier (BBB) is a dynamic interface evolved to protect the brain from exposure to toxic xenobiotics and to maintain homeostasis. Distribution of drugs across BBB is critical for any drug discovery project. A drug designed for a target in brain has to pass through the BBB in sufficient concentr

The cost of Poor Quality. Increasing the Transparency of Quality in Tetra Pak Capital Equipment´s Supply Chain

Contemporary business trends are more and more shifting focus to the requirements of the customers. One of the most important factors for the customer is quality, both in the interface with the selling company and in the products sold. Tetra Pak is a pioneer within the packaging of diaries and food. The company has been profitable in most situations which have created a state of mind where quality

Behavioral and Biological Factors Related to HIV Transmission among Female Sex Workers in Ethiopia

Due to legal, cultural, and social factors, female sex workers (FSWs) experience anelevated level of violence, heavy alcohol consumption, and sexual abuse. Theseindividual and societal factors create a web of vulnerabilities that facilitate thespread of HIV within this population group. Moreover, stigma and discriminationare common among HIV-positive FSWs, contributing to poor HIV treatmentadheren

On the road to life satisfaction for person's with Parkinsons disease

Parkinson’s disease (PD) is one of the most common neurodegenerative disorders. The motor and non-motor symptoms of PD lead to a number of consequences in everyday life for persons with PD (PwPD). PwPD continuously need to adapt to their new life situation and despite medical treatment, the impact of PD on everyday life is inevitable and can lead to a lower level of life satisfaction (LS). LS is a

Exploring the Milky Way stellar disk A detailed elemental abundance study of 714 F and G dwarf stars in the solar neighbourhood

Aims. The aim of this paper is to explore and map the age and abundance structure of the stars in the nearby Galactic disk. Methods. We have conducted a high-resolution spectroscopic study of 714 F and G dwarf and subgiant stars in the Solar neighbourhood. The star sample has been kinematically selected to trace the Galactic thin and thick disks to their extremes, the metal-rich stellar halo, sub-

Epidemiological, mechanistic and genetic aspects of vascular ageing and arterial stiffness in the population

The core feature of vascular ageing is the age-associated stiffening of the large, elastic arteries, or arteriosclerosis. This results in a diminished volume-buffering function and is therefore central for the increase in systolic blood pressure and pulse pressure seen with advancing age. Since there are considerable individual differences regarding the rate of vascular ageing, the aim was to desc

Structural and Functional Analyses of Xyloside-primed Glycosaminoglycans

Glycosaminoglycans (GAGs) are polysaccharides produced by essentially all mammalian cells. Due to their enormous structural diversity, they are involved in many biological processes both in health and disease, including all stages of tumor progression. GAGs are normally attached to a core protein as a part of a proteoglycan; however, GAG biosynthesis can be induced by compounds composed of a xylos

The confluence of Cloud computing, 5G, and IoT in the Fog

In the wake of the arrival of cloud computing, future applications are poised to become more resilient and adaptive by embracing elasticity in an osmotic manner. Although cloud computing is a strong attractor for application developers, thereare still unconquered performance frontiers. Latency-sensitive and missioncritical applications make up a significant portion of all software systems, and the

Evaluation of the breath-hold approach in proton therapy of lung tumors

Proton therapy has the potential to improve the local control rates and reduce the risk of toxicity forlung cancer patients. However, the delivery of proton therapy is prone to uncertainties caused byanatomical changes and motion during the treatment and between the treatment fractions whichmay compromise its effectiveness. The dosimetric uncertainty of lung cancer proton therapy can beminimized t

Long-term prognosis with home hemodialysis. A comparison with other renal replacement therapies.

Background: The annual mortality for patients on dialysis is high even if it has decreased from 30 % in 1991 to 18 % in 2016. It is mainly caused by an increased cardiovascular and infectious morbidity. Previous studies have reported improved survival for patients with home hemodialysis (HHD). However, patients starting HHD are younger and healthier compared to patients starting other dialysis mod

Submission to UN High Level Panel on Internal Displacement - The Raoul Wallenberg Institute of Human

Submission to UN High Level Panel on Internal Displacement - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outr

https://rwi.lu.se/news/submission-to-un-high-level-panel-on-internal-displacement/ - 2026-06-19

Microsoft Word - ARK A02.2 exam.doc

Microsoft Word - ARK A02.2 exam.doc Arkeologi Institutionen för arkeologi och antikens historia Lunds universitet ARK A02, Arkeologi fortsättningskursen, höstterminen 2010 Delkurs 2: Perspektiv och metodik inom järnåldersforskningen, 5 hp Examination Examinationen är uppdelad i två delar, dels en seminariediskussion, dels en skriftlig inlämningsuppgift baserad på presentationen och diskussionen. S

https://www.ark.lu.se/media/utbildning/dokument/kurser/ARKA02/20102/ARK_A02.2_exam.pdf - 2026-06-19

Gender Audit Training for the Zimbabwe Gender Commission Staff (8-11 July 2025) - The Raoul Wallenbe

Gender Audit Training for the Zimbabwe Gender Commission Staff (8-11 July 2025) - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Adv

https://rwi.lu.se/news/gender-audit-training-for-the-zimbabwe-gender-commission-staff-8-11-july-2025/ - 2026-06-19

About us

About us | Saco-S föreningen vid Linnéuniversitetet Hoppa till huvudinnehåll About us Contact Salary Working hours Laws & agreements Current Newsletter June 2026 Newsletter April 2026 Newsletter December -25 Newsletter November -25 Saco-S AGM October 7, 2025 Newsletter June -25 Newsletter December -24 Newsletter November -24 Saco-S AGM October 2, 2024 Newsletter June -24 Newsletter December -23 Ne

https://www.saco.se/en/trustee/local-union-work/local-unions/government-sector/saco-s-foreningen-vid-linneuniversitetet/about-us/ - 2026-06-19

Allman studieplan for utbildning pa forskarniva i fri konst 170531 0

Konstnär l iga fakulteten i Malmö Dnr: U 2017/225 Allmän studieplan för utbildning på forskarnivå i fri konst ledande till konstnärlig doktorsexamen 1. Identifikation Utbildningsnamn och inriktning: Utbildning på forskarnivå i fri konst Ämneskod: KOKOFK01 Omfattning i högskolepoäng: 240 Nivå: Forskarnivå Examensbenämning: Konstnärlig doktorsexamen i fri konst Engelsk examensbenämning: Doctor of Ph

https://www.konstnarliga.lu.se/sites/konstnarliga.lu.se/files/allman_studieplan_for_utbildning_pa_forskarniva_i_fri_konst_170531_0.pdf - 2026-06-19

Birtele et al-2019-febs letters

Dual modulation of neuron‐specific microRNAs and the REST complex promotes functional maturation of human adult induced neurons This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/birtele_et_al-2019-febs_letters.pdf - 2026-06-19

No title

Insta l lat ionen äger rum i Lunds univers i tets aula fredagen den 14 oktober 2011 kl 16.00 Professorsinstallation 3 Förord Välkomna till den högtidliga professors­ installationen! ordet universitet kommer av det latinska universitas, som betyder ungefär helhet, det hela. detta ord har samband med universus med betydelsen hel, allomfattande, egentligen vänd åt ett håll, liksom med universum och u

https://www.vetenskaphalsa.se/wp-content/uploads/2011/10/Professorsinstallationsbroschyr_ht2011_lowNY.pdf - 2026-06-16

INSTÄLLT: Högre seminarium med fokus på litteraturdidaktisk forskning: Den litterära kanon i Sverige

INSTÄLLT: Högre seminarium med fokus på litteraturdidaktisk forskning: Den litterära kanon i Sverige - ett rörligt mål | The joint faculties of humanities and theology 11 May INSTÄLLT: Högre seminarium med fokus på litteraturdidaktisk forskning: Den litterära kanon i Sverige - ett rörligt mål 11 May 2026 15:15 to 16:45 Seminar Måndag den 11 maj är det dags för nästa seminarium med fokus på littera

https://www.ht.lu.se/en/the-faculties/whats-on/calendar/event/installt-hogre-seminarium-med-fokus-pa-litteraturdidaktisk-forskning-den-litterara-kanon-i-sverige - 2026-05-05