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Efficient scope management is a core part of software release management and often a key factor in releasing successful software products to the market. In a case when not all the requirements for the next software product release are known ‘a priori’ and when new requirements are issued throughout the project, the risk of overscoping by including more functionality than can be implemented increas
Geologists have long recognized the magnitude, abruptness, and the global pattern of the major biotic turnover across the Cretaceous–Paleogene (K–Pg) boundary approximately 65.5 million years ago. It was associated with one of the most catastrophic events in the history of life, involving mass mortality in both terrestrial and marine ecosystems globally; vast amounts of dead biomass covered the Ea
Using geopotential height data we find a strong correlation between theelectric field strength E of the solar wind and pressure variations inthe stratosphere and troposphere. The large-scale evolution of E seemsto influence the stratospheric pressure in both hemispheres with theexception of the polar regions. For the tropospheric pressure theinfluence is concentrated to an area in the northern Atl
Energy simulation programs are commonly used to calculate the climate and energy requirements in glazed spaces and adjacent buildings. However, these programs have usually been developed to study buildings with ordinary window sizes. Comparisons of four simulation programs were carried out for a sunspace with an adjacent room. The distribution of solar radiation between the glazed space and the ad
This article presents an analog implementation of the signal component generator (SCG) of the CALLUM2 linear transmitter architecture. The proposed SCG is suited for integration in a standard 0.35 μm CMOS process, and has from simulations proven to be adequate when operating on an EDGE modulated baseband signal with a data rate of 270.833 ksymb/s. The total current consumption of the SCG is 2.0 mA
Out of 369 diabetic patients with an age at onset of diabetes > or = 30 years previously studied, 325 (88%) were included in an ophthalmological follow-up examination 4 years later. In patients treated with oral drugs at baseline, the incidence of any type of retinopathy was 30.8% and of severe retinopathy 5.7%. All patients who developed severe retinopathy received insulin during the follow-up pe
Classical control has serious limitations when faced with solids separation problems in the activated sludge process. Lack of knowledge about the mechanisms involved in the imbalance within the different microbiological communities implies that a general solution to these undesirable situations has not yet been provided. However, operators have to make decisions based on their experience and intui
PURPOSE: To assess the diagnostic efficacy, safety and tolerability of mangafodipir trisodium (MnDPDP, Teslascan) in MR imaging of the liver. MATERIAL AND METHODS: Eighty-two patients from 4 centres underwent MR imaging with pre-contrast sequences including T1-weighted SE and GRE, and T2-weighted turbo SE sequences. MnDPDP at a dose of 5 mumol/kg b.w. was administered by slow i.v. infusion, and 20
The first rapidity density distributions from relativistic collisions between truly heavy nuclei are presented. The distributions are compared with expectations from a linear extrapolation of results obtained from collisions with lighter nuclei. Fluctuations are essentially described by a simple scenario with stochastic emission.
In the framework of the semi-hard (k(t)-factorization) approach, we analyze the various charm production processes in the kinematic region covered by the HERA experiments.
The aim of this study was to analyse whether the interleukin-1 (IL-1) and IL-6 gene polymorphisms were associated with the susceptibility of chronic periodontitis. Genomic DNA was obtained from 20 patients with chronic periodontitis and 31 periodontally healthy subjects. All subjects were of North European heritage. The test subjects were kept in a maintenance program after periodontal treatment b
The mechanism of transmembrane polyamine internalization in mammalian cells remains unknown. A novel fluorescent spermidine conjugate [Spd-C(2)-BODIPY; N-(4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacene-3-propionyl)-N' -(S -[spermidine-(N(4)-ethyl)]thioacetyl)ethylenediamine] was synthesized from N(4)-(mercaptoethyl)spermidine by a simple, one-step coupling procedure. In Chinese-hamster ov
We have identified a new cyclic-nucleotide phosphodiesterase isoform, PDE3A, and cloned its cDNA from cultured aortic myocytes. The nucleotide sequence of its coding region is similar to that of the previously cloned myocardial isoform except for the absence of the initial 300-400 nt that are present in the latter, as confirmed by reverse-transcriptase-mediated PCR, 5' rapid amplification of cDNA
The aim of this study was to investigate a new extracorporeal immunoadsorption method to improve tumor-to-normal tissue ratios in radioimmunoimaging (RII) and radioimmunotherapy (RIT). We have developed and investigated a general method using biotinylated antibodies and an agarose-avidin column for extracorporeal immunoadsorption. The studies were made in an animal model and extracorporeal immunoa
Sweden is among those countries in Europe that have the lowest number of organ donors per million population (PMP). Because of the low numbers of actual donors, it is important to identify the total number of potential donors. Thus, a prospective registration of all deceased patients at all intensive care units was introduced in the Southern Healthcare Region of Sweden, which has a population of 1
