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INTRODUCTION: We evaluated differences in p-tau levels between Alzheimer's disease (AD), a condition with brain-specific changes in p-tau, and amyotrophic lateral sclerosis (ALS), a condition associated with increases in peripheral p-tau levels. METHODS: Cerebrospinal fluid and plasma from 668 participants were analyzed using immunoassays specific for the low-molecular-weight (LMW) tau isoforms pr
In the past years, anti-genderism has become a growing force in politics. The word ‘gender’ has become an empty signifier to attack queer and feminist agendas, sexual and reproductive rights but also gender studies scholars and courses. Social media, particularly Twitter stands out in the spread of anti-genderism despite its 280-character limit. Using political netnography and feminist critical di
Cannabisaktivism, en del av Argentinas bredare tradition av sociala rörelser, har utvecklats till ett dynamiskt fält för motstånd och påverkansarbete – särskilt när det gäller medicinsk cannabis, som hamnade i fokus år 2015. Faktum är att min avhandling tog sin startpunkt i och med att jag etablerade kontakt med Mama Cultiva, en sammanslutning av mödrar, som spelade en aktiv roll i skapandet av enCannabis activism, which is embedded in Argentina’s broader tradition of social movements, has become a dynamic field of resistance and advocacy, particularly regarding medicinal cannabis, which came into focus in 2015. Indeed, the research for my thesis began by establishing contact with Mama Cultiva, a mothers’ organisation that played an active role in the creation of a new cannabis law and dra
Precise knowledge of the temperature during cutting processes is of high interest as the temperature of a cutting tool dictates the performance, and for the workpiece it controls the quality and integrity of the generated surface. For the first time, in this study, a novel technique has been developed utilizing phosphor thermometry for 2D surface temperature measurement of a cutting tool in metal
Background/Objectives: There is still no consensus as to whether patients with upfront resectable synchronous colorectal liver metastases (sCRLM) should receive neoadjuvant treatment prior to liver surgery. Two randomized controlled trials have assessed the role of peri-operative chemotherapy in sCRLM; neither have shown a survival benefit in the neoadjuvant group. The aim of this population-based
Introduction: Malaria remains a persistent challenge in global health, disproportionately affecting populations in endemic regions (eg, sub-Saharan Africa). Despite decades of international collaborative efforts, malaria continues to claim hundreds of thousands of lives each year, with young children and pregnant women enduring the heaviest burden. This concise review aimed to provide an up-to-dat
Portal hypertension (PH) is a major complication of chronic liver disease, often leading to serious clinical consequences such as variceal bleeding, ascites, and splenomegaly. The current gold standard for PH diagnosis, namely, hepatic venous pressure gradient measurement, is invasive and not widely available. Transient elastography has emerged as a non-invasive alternative for assessing liver sti
The feasibility of South Africa's just energy transition, as dictated by the speed of phasing out coal and scaling up renewables, will rest on a range of techno-economic, socio-political, and socio-technical factors. Interactions between these dimensions of the transition carry significant implications for energy justice. In response, this paper proposes the Just Transition Feasibility Framework (
Policing roles require specific work-related characteristics (WRCs) critical for effective performance. This study identifies key WRCs for various roles within the Swedish Police—patrol officers, criminal investigators, Special Weapons and Tactics (SWAT) Teams, police chiefs, and negotiators—by analyzing data from 425 active-duty officers (30% response rate). We use the Occupational Information Ne
Mot bakgrund av tilltagande ekologiska kriser, växande socioekonomiska ojämlikheter och ett klimat i förändring har behovet av att omvandla jordbrukssystem mot hållbarhet och rättvisa blivit alltmer akut. En sådan omvandling hindras emellertid ofta av djuprotade strukturer och institutionella arrangemang som gynnar snävt definierade föreställningar om produktivitet och marknadseffektivitet. DärigeAmid escalating ecological crises, widening socio-economic inequalities, and intensifying climate change, the imperative to transform agricultural systems towards sustainability and equity has become increasingly urgent. Yet suchtransformation is often hindered by entrenched institutional and structural arrangements that privilege narrowly defined notions of productivity and market efficiency, the
Purpose: The sugar industry is always pressured to be suitable and enhance its operational effectiveness. Digital Twin (DT) has the potential to transform this industry. However, the lack of industry-specific Key Performance Indicator (KPI) frameworks makes it challenging to implement them. This study provides a hierarchical KPI model for DT adoption in the sugar sector, interconnecting the United
Background: Psychological resilience refers to a person's positive adaptation when faced with adversities, such as a breast cancer (BC) diagnosis. Highly resilient patients are more likely to regain stability and be protected from health conditions such as depression, anxiety, and posttraumatic stress disorder. We aimed to identify epigenetic markers that distinguish high- and low-resilient patien
PURPOSE: Given the paucity of data regarding workplace risk of COVID-19, particularly from countries with limited lockdowns, we aimed to quantify the occupational risks of COVID-19-related hospital admission among workers in Sweden.METHODS: We identified 607,179 employed individuals, 20-69 years of age, in Skåne, Sweden. From December 31st, 2019-December 31st 2021, 2,633 incident COVID-19-related
Over the last two decades, the social identity of the jihadist has become a central part of street culture. Depictions of jihadists can be found in popular music, movies and media reports. Propaganda celebrating or condemning jihadism circulates online, and a significant number of individuals with a background in street crime have flirted with or converted to jihadism. Drawing on ethnographic fiel
Article 12 of the UN Convention on the Rights of Persons with Disabilities requires states parties to take appropriate measures to ensure that persons with disabilities have access to the support they may need in exercising their legal capacity. However, this obligation remains ambiguous. What exactly is decision-making support meant to accomplish? Until this fundamental issue has been clarified,
The purpose of this paper is to explore context adaptation of change processes in the setting of public administration. This is done by adopting a contingency approach. Thus, the research question guiding this study is: How is context adaptation enacted in change processes and what are the behavioural implications? Drawing on empirical findings from the Swedish Transport Administration, the study
This study investigates how the seven core resilience principles are integrated into assessments of forest system resilience to natural or human-induced disturbances across engineering, ecological, and social-ecological resilience concepts. Following PRISMA guidelines, a literature search in the Web of Science database using the keywords “resilience”, “forest” and “ecosystem services” yielded 1828
Homelessness has increased significantly in Sweden since the early 1990s. A national surveyof homelessness in 2023 showed that 27,383 people were in one of the four homelessnesssituations that are recognised in Sweden, namely: (a) acute homelessness; (b) institutional orsupported housing; (c) long-term housing organised by a municipality; and (d) short-termaccommodation arranged by people themselv
