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Objective: Emergency complex abdominal aortic diseases are challenging to treat. During in situ laser fenestration (ISLF), aortic branches are covered and flow is restored by in situ fenestration of the stent graft, with promising midterm results. This study aimed to expand on the limited body of knowledge of midterm outcomes of ISLF in renovisceral aortic pathology in a multicentre setting. Metho
Most cutaneous malignant melanomas (CMMs) are thin (≤1.0 mm, stage T1) with an expected 10-year melanoma-specific survival of 93%–97%. The incidence of CMM is higher in groups with high socioeconomic status (SES). We aimed to assess overall survival (OS) and detailed characteristics in individuals with thin CMM as compared to the general population matched on age, sex, and county of residence. Mat
Despite growing emphasis on home-based rehabilitation following stroke, there remains limited understanding of how to effectively tailor services to individual needs. This study employed concept mapping to explore diverse stakeholder perspectives on adapting home-based rehabilitation to better support the recovery process after stroke. Through this mixed-methods participatory approach, we engaged
Genetically determined color morphs are found in many animals. Polymorphism can be maintained by social selection if competitive interactions allow each morph to increase in frequency when rare. This reliance on negative frequency-dependent selection should make color polymorphism vulnerable to the appearance of novel phenotypes that disrupt competitive interactions among morphs. We show that the
We explore mission assignment and task offloading in Open Radio Access Network (Open RAN)-enabled intelligent transportation systems (ITS), where autonomous vehicles utilize mobile edge computing for efficient processing. Existing studies often overlook mission dependencies and offloading costs, leading to suboptimal decisions. To address this, we formulate a novel optimization problem that integr
Background: Procalcitonin (PCT) is a biomarker used to differentiate between viral and bacterial infections, though the underlying mechanisms are not yet fully understood. This study aimed to identify genetic variants associated with plasma PCT concentrations and explore the associations of genetically predicted PCT with a wide range of disease related traits in a PheWAS. Methods: We conducted GWA
With sea-level rise and increasingly frequent extreme weather events threatening communities, ecosystems and built infrastructure alike, climate change adaptation is pressing. This remains true in high-income countries where research capturing power dynamics underpinning adaptation continues to develop with implications for how policy and exclusion can be understood. Through a systematic review, t
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKp) represents a growing clinical threat due to convergence of resistance and virulence determinants. We conducted a multicenter genomic epidemiology study analysing CR-hvKp isolates collected from 19 tertiary-care hospitals across Türkiye between 2018 and 2023. CR-hvKp isolates were subjected to whole-genome sequencing to investigate
Sentinel lymph node biopsy (SLNB) remains the standard method for axillary staging in breast cancer. However,for the majority of patients with early breast cancer, it offers no treatment benefit and carries a risk of long-termside effects. In the era of surgical de-escalation, reliable preoperative assessment of axillary lymph node metastasis isessential to avoid overtreatment and support treatmen
Urban meteorology, the study of atmospheric phenomena in urban areas, is vital for understanding the dynamic interactions between rapid urbanization and environmental changes. Over the past two decades (2004–2024), urban heat islands (UHIs), extreme rainfall, pollution, and temperature anomalies have intensified, adversely affecting human health, infrastructure, and ecosystems worldwide. The prese
Background and AimsThe life expectancy of adult patients with congenital heart disease (ACHD) has improved, thus shifting the research focus towards age-related comorbidities to continue to improve patient outcomes. This study aimed to investigate all-cause mortality and recurrent acute myocardial infarction (AMI) in adults with and without congenital heart disease.MethodsA nationwide case control
Topological qubits based on non-Abelian Majorana bound states (MBSs) are protected by parity which is challenged by quasiparticle poisoning (QPP). In this work, we show how QPP affects transport through a pair of coupled MBSs weakly connected to two current leads, using an open system approach and full counting statistics. We find that the correct low-energy physics requires one to include next to
Background: Clinical supervisors’ competence is central to student learning, particularly in the context of existing practical, organizational, and resource-related challenges in simulation-based education. This study explored clinical supervisors’ experience of acting as instructors during simulation-based learning in specialist nursing education in anesthesia and intensive care. Method: An explo
Populärvetenskaplig sammanfattning: Under året 2001 kom forskare i hela världen överens om att globala klimatförändringar existerar och att människliga aktiviteter har påverkat dem, framförallt genom utsläpp av koldioxid (CO2). Kyoto Protokollet är en global överenskommelse som kräver en minskning av CO2 utsläpp (med 1990 som basår) och fem andra växthusgaser med 5% fram till 2012. Ett sätt som näIn 2001, the Intergovernmental Panel on Climate Change approved human impact (mainly through the emission of carbon dioxide (CO2)) on global warming. The Kyoto Protocol is a global contract that proposes the reduction of CO2 and five other greenhouse gases by 2012 to at least 5% below the level of 1990. One reduction strategy included in the Protocol is the Clean Development Mechanism (CDM). It su
Bakgrund: De centrala delarna av Vietnam har en årlig nederbörd på 4000 mm/år och det är vanligt med hastigt uppkomna översvämmningar (s.k. flash floods) här. Flash floods är plötsliga översvämmningar med ett högt flöde producerade av kraftiga regn. De sker oftast under natten och ger ofta upphov till jordskred. År 1999 skedde det en stor översvämning som spred sig 200 km längs kusten och dödade ö
This Master Thesis states that organisations based on ethnicity should be included in the concept of civil society. The argumentation originates in that the existing definitions of civil society exclude organisations based on ethnicity. This proves to have troublesome consequences in an African context, since a large part of the associational life can be derived to ethnicity. Based on the assumpti
This study evaluates the international production fragmentation and the specialization of the textile and apparel sector in the ASEAN countries. Moreover, it examines Thailand’s participation in textile and apparel supply-chains with the aim of finding prospects for more value-added production. The finding of the study is that production fragmentation only exists to a small extent in the ASEAN cou
Globalization and the deregulation of currencies have had a negative impact on the domestic tax systems of states and the tax bases on which these rely. Tax policies of sovereign states have, historically, been the means of maintaining a high standard of public services why reduced tax bases could arguably be a threat to the welfare state. The proliferation of tax havens and increased use of tax d
