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Abstract in UndeterminedModern irrigation techniques are becoming increasingly important in water-scarce countries. In this study, a two-dimensional water and solute transport model, Hydrus-2D, was used to assess the impact of inter-plant emitter distance (IPED) and irrigation water salinity on soil moisture and salinity distribution as well as on water balance components under alternate partial r
Inflammation influences several steps of adult neurogenesis, but whether it regulates the functional integration of the new neurons is unknown. Here, we explored, using confocal microscopy and whole-cell patch-clamp recordings, whether a chronic inflammatory environment affects the morphological and electrophysiological properties of new dentate gyrus granule cells, labeled with a retroviral vecto
The study is based on data collected at the LEP II accelerator during the second period of the Large Electron-Positron collider operations (1996-2000). During that time the DELPHI (DEtector with Lepton, Photon and Hadron Identification) experiment collected about 90 Gb of data on tape corresponding to 687-691 pb-1 of luminosity. The data obtained by the VSAT (Very Small Angle Tagger) e
Background Exposure to inorganic arsenic increases the risk of cancer and non-malignant diseases. Inefficient arsenic metabolism is a marker for susceptibility to arsenic toxicity. Arsenic may alter gene expression, possibly by altering DNA methylation. Objectives To elucidate the associations between arsenic exposure, gene expression, and DNA methylation in peripheral blood, and the modifying eff
Previous research found that weight-related behaviors and body weight tends to be similar between individuals and peers. Rather little is known how different domains of weight-related behaviors co-evolve in peer networks. Hence, this study explores how young adults’ self-reported dieting relates to perceived body weight and weight control behaviors of their peers. A Swedish two-wave panel survey w
Corticosterone exposure during prenatal development as a result of maternal upregulation of circulating hormone levels has been shown to have effects on offspring development in mammals. Corticosterone has also been documented in egg yolk in oviparous vertebrates, but the extent to which this influences phenotypic development is less studied. We show that maternal corticosterone is transferred to
An experiment was conducted to follow the fate of the cyanobacterial toxin, nodularin, produced by Nodularia spumigena through ingestion by Mytilus edulis and re-ingestion of faecal material (coprophagy). Mussels were fed with cultures of N. spumigena, and the faeces that were produced were fed to other mussels not previously exposed to N. spumigena. Concentrations of nodularin were measured in th
The recreational drug ecstasy [3,4-methylenedioxymethamphetamine (MDMA)], has been found to selectively damage brain serotonin neurons in experimental animals, and probably in human MDMA users, but detailed morphometric analyses and parallel functional measures during damage and recovery are missing. Since there is evidence that serotonin regulates sleep, we have compared serotonergic markers para
Calbindin D28k (calbindin) is a member of the calmodulin superfamily of Ca2+ -binding proteins. An intracellular target of calbindin was discovered using bacteriophage display. Human recombinant calbindin was immobilized on magnetic beads and used in affinity purification of phage-displayed peptides from a random 12-mer peptide library. One sequence, SYSSIAKYPSHS, was strongly selected both in the
BACKGROUND: Recent studies have suggested that Bacille Calmette-Guerin (BCG) vaccination may have a non-specific beneficial effect on infant survival and that a BCG scar may be associated with lower child mortality. No study has previously examined the influence of BCG vaccination on cause of death. METHODS: Two cohorts (A and B) were used to describe the mortality pattern for children with and wi
Popular Abstract in Swedish Målsättningen med avhandlingen är att analysera vilken roll småskaligt entreprenörskap som alternativ överlevnadsstrategi har spelat i Sierra Leone under den ekonomiska kris som drabbade landet efter självständighet på 1960-talet. Avhandlingen baseras på nätverksteori, snowball metod och det empiriska underlaget utgörs av en studie av utvecklingen i Sierra Leone, med avSierra Leone is a small country with rich mineral resources such as diamonds, bauxite, gold and iron ore. Other resources include fishing, forestry and fertile agricultural land, which enable people to farm without any sophisticated methods of mechanization. Nevertheless, with all its wealth in resources, the country is relatively poor and is one of the least developed countries in the Sub-Saharan
Uptake capacity of organic nitrogen was studied in solution experiments on eight grasses and two forbs growing in acid soils with relatively high nitrogen mineralisation in southern Sweden. Uptake of a mixture of amino acids (alanine, glutamine, glycine), that varied between 1.6 and 6.3 mu mol g(-1) dw root h(-1), could not be explained by soil data from the species' field distributions (pH, total
Popular AbstractI Sverige har utbildningspolitiken under de senaste decennierna fått en viktig roll i att främja målsättningar också inom en rad andra politikområden, bland annat det regionalpolitiska. Högskolorna skall bidra till att utjämna sociala och ekonomiska skillnader mellan olika grupper i befolkningen, stimulera innovationsförmågan i näringslivet och generera nya företag. UndersökningarnImportant goals in Swedish higher education policy, from the late 1960s all through the 1990s, have been to increase the accessibility to higher education and to increase the supply of newly educated labour in all parts of the country. These goals are based on the assumption that geographical distance matters. Geographical distance to universities is thought to act as a barrier to university entra
The intracellular signal cascade transducing muscarinic-receptor-stimulation to gene expression was investigated in human neuroblastoma SH-SY5Y cells. Naive and ethanol-exposed SH-SU5Y cells were stimulated with carbachol (CCh) and inositol 1,4-5-trisphosphate (IP3), 1,2-diacylglycerol (DAG), and c-fos mRNA levels were analyzed using a radioreceptor assay (IP3) thin-layer chromatography (DAG) and
Bruton's tyrosine kinase (Btk) is a nonreceptor tyrosine kinase, critical for B-cell development and function. Mutations that inactivate this kinase were found in families with X-linked agammaglobulinaemia (XLA). In this study the Btk gene was analyzed in 13 registered Greek patients with XLA phenotype originated from 12 unrelated families, in order to provide a definite diagnosis of the XLA. The
Background In spite of significant safety measures, allergy to industrial enzymes remains a major concern. The increasing prevalence of occupational allergy emphasizes the need to investigate the functional properties of enzyme-exposed dendritic cells (DCs), as DCs possess a potent ability to activate allergen-specific T cells. Objective This study aims at elucidating the molecular mechanisms unde
In many studies, particularly in the field of systems biology, it is essential that identical protein sets are precisely quantified in multiple samples such as those representing differentially perturbed cell states. The high degree of reproducibility required for such experiments has not been achieved by classical mass spectrometry-based proteomics methods. In this study we describe the implement
Leukotriene B-4 (LTB4) is a potent lipid mediator of inflammation that acts primarily via a seven-transmembrane-spanning, G-protein-coupled receptor denoted BLT1. Here, we describe the synthesis and characterization of fluorescent analogs of LTB4 that are easy to produce, inexpensive, and without the disadvantages of a radioligand. Fluorescent LTB4 is useful for labeling LTB4 receptors for which n
