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Leukotriene B-4 (LTB4) is a potent lipid mediator of inflammation that acts primarily via a seven-transmembrane-spanning, G-protein-coupled receptor denoted BLT1. Here, we describe the synthesis and characterization of fluorescent analogs of LTB4 that are easy to produce, inexpensive, and without the disadvantages of a radioligand. Fluorescent LTB4 is useful for labeling LTB4 receptors for which n
This thesis argues that the current urban transport in Vienna, which is characterized by extensive usage of cars, is too material-intense (both in terms of input and output) and from a social perspective inherently un-urban. It therefore concludes that effective transport policy should aim at following a new imaginary, one that is based on the aim of de-materializing and “re-urbanizing” the mobili
A signal with harmonic structure is often characterized by its fundamental frequency, or pitch. This single parameter contain vital information of a range of applications such as musical transcription, tuning of stringed instruments, speech processing and more. Some signal sources, for instance a sti vibrating string, exhibit waveforms with slightly deviating harmonic structure. This phenomenon is
This thesis is based on a quantitative study that is conducted by comparing the fundraising effectiveness of humanitarian non-profit organisations (NPOs) to their program expenditure. The fundraising effectiveness of NPOs is derived from fundraising expenses over donations received. Using two hypotheses that were developed using literature revolving around capabilities, with a special focus on mar
This thesis aims to provide a deeper understanding of how Business Angels (BA) investment process and criteria are impacted by entrepreneurial competencies (EC) when assessing the founding team during the screening phase. This study reinforces the definition of entrepreneurial competencies by bringing a new perspective on how these competencies can be classified and enhances the implication of the
Glioblastoma (GBM) is the most aggressive type of primary brain tumours in adults and accounts for 49.1% of the cases. Most of the cases are recorded in elderly patients, but GBM affects people of all age groups. Till date no cure has been found. Previous data has suggested that pericytes might influence tumour invasion by interacting with tumour cells by the secretion of or interaction with extra
Background: Reliable exposure data is a vital concern in medical epidemiology and intervention studies. The present study addresses the needs of the medical researcher to spend monetary resources devoted to exposure assessment with an optimal cost-efficiency, i.e. obtain the best possible statistical performance at a specified budget. A few previous studies have suggested mathematical optimization
Syfte: Syftet med uppsatsen är att undersöka vad som styr priset på olika typiska kontorsmateriel och att med stöd av resultaten peka på områden som kan förbättras. Metod: Metoden är deduktiv, kvantitativ och använder regressionsanalyser såväl som deskriptiv statistik för att beskriva data. Teoretiska perspektiv: De hypoteser som testas vilar på teori om auktioner. Empiri: Empirin består av ett st
Vikten av resurseffektivitet i livsmedelskedjan är tydlig, eftersom denna sektor är en av de största bidragarna till negativ klimatpåverkan globalt. Målet med den här uppsatsen var att utforska sidoströmmar av mat inom livsmedelskedjan i Västra Götaland, för att kartlägga hur mycket som redan är täckt i statistiken och vilka luckor i datamaterialet som finns för framtida forskning att täcka. DessThe importance of resource efficiency in the food supply chain is clear, since this sector is one of the biggest contributors to the negative environmental impacts globally. This thesis project aimed to examine food side streams throughout the food supply chain in Västra Götaland, to map out how much has already been covered statistically and what gaps there are in the data for future research to
Studien syftar till att undersöka musiklärares förhållningssätt till extra anpassningar och vilka metoder de använder för att göra undervisningen begriplig för alla elever. Arbetet syftar även till att ta reda på om de intervjuade musiklärarna i studien upplever att de får den hjälp de behöver i sitt arbete med extra anpassningar och särskilt stöd. Genom en enkätundersökning ges även en inblick i The study aims to investigate the approach of music teachers to extra adaptations and the methods they use to make teaching understandable for all students. The work also aims to find out if the interviewed music teachers in the study feel that they receive the help they need in their work with extra adaptations and special support. A survey also provides an insight into how students perceive musi
Historical sources written in rare or undeciphered scripts represent an immense but underexploited part of the world’s cultural and linguistic heritage. Their study is often hindered by fragmentary preservation, non-standard symbol systems, and the absence of interoperable digital resources. While recent advances in imaging, transcription, and computational analysis have improved access to histori
Syftet med uppsatsen är att undersöka vad som avgör hur tillväxtföretag värderas. Det inkluderar att jämföra om dessa företag värderas på samma sätt i teorin som i praktiken och undersöka vilka bakomliggande faktorer som spelar in. Den teoretiska referensramen inkluderar teori om värderingsmodellerna realoptioner, diskonterat kassaflöde och multipelvärdering. Den inkluderar även teorier om de bako
This paper aims to investigate whether there is a need for two regulations since Chapter 16 Section 9 of the Penal Code and the Discrimination Act from 2009 both regulate the same area of discrimination. The first regulation, Chapter 16 Section 9 of the Penal Code, regulates unlawful discrimination based on the grounds of race, colour, ethnic origin or sexual orientation. The second regulation, thUppsatsen syftar till att utreda om det finns ett behov av både 16 kap 9§ BrB och Diskrimineringslagen från år 2009 eftersom de behandlar samma diskrimineringsområde. 16 kap 9§ BrB reglerar olaga diskriminering baserat på ras, hudfärg, etnicitet och sexuell läggning. DiskL reglerar samma diskrimineringsgrunder som 16 kap 9§ BrB, men även funktionshinder, kön och ålder. Uppsatsen avser även att und
