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BACKGROUND: Symptom reduction occurring early in depression treatment is associated with favourable post-treatment outcome, but it is not known how early reduction in specific depression symptoms affect treatment outcome. We aimed to determine the impact of symptom-specific change from pre-treatment to week four during internet-delivered CBT (ICBT) on overall and symptom-specific depression severi
With the amendment to the German Climate Change Act in 2021, the Federal Government of Germany has set the target to become greenhouse gas neutral by 2045. Reaching this ambitious target requires multisectoral efforts, which in turn calls for interdisciplinary collaboration: the Net-Zero-2050 project of the Helmholtz Climate Initiative serves as an example of successful, interdisciplinary collabor
Background: During the initial phase of the COVID-19 pandemic, reductions in air pollution were globally observed owing to decreased human activities, underscoring the potential for cleaner air through shifts in human behaviour. Objectives: The objective of the present study was to hypothetically estimate the resulting population health impacts in Malmö, Sweden, if these improvements in air qualit
In recent years, there has been a wave of opposition to feminism, gender equality, and minority rights in various national and international contexts. While there is a growing number of works that examine anti-gender campaigns, less attention has been devoted to the potential consequences of the anti-gender mobilizations for the internal relations within socially progressive (feminist and LGBTQ+)
Time delay estimation or Time-Difference-Of-Arrival estimates is a critical component for multiple localization applications such as multilateration, direction of arrival, and self-calibration. The task is to estimate the time difference between a signal arriving at two different sensors. For the audio sensor modality, most current systems are based on classical methods such as the Generalized Cro
The importance of nucleic acids in pure form for preparative and analytical perspectives, have increased constantly, demanding the development of new and more efficient methods for their recovery and isolation. This thesis describes a series of different innovative methods for recovery and purification of these biomolecules. In a general overview of a downstream processing, there are several criti
BACKGROUND: We investigated ophthalmological outcomes at 2.5 years of corrected age in children born extremely preterm (EPT) to evaluate the effects of postnatal enteral supplementation with ω-3 and ω-6 long-chain polyunsaturated fatty acids.METHODS: In the Mega Donna Mega clinical trial, EPT infants born at less than 28 weeks of gestation were randomized to receive an enteral supplementation of d
OBJECTIVE: Many GH deficient (GHD) patients have impaired glucose tolerance and GH substitution in these patients has caused deleterious effects on glucose tolerance with hyperinsulinaemia. This further impairment of glucose tolerance might be due to an unphysiologically high dose of GH. Whether such a deterioration can be avoided by an optimal GH replacement dose is not known. In most previous st
Ultra-high-frequency ultrasound (UHFUS) has a reported potential to differentiate between aganglionic and ganglionic bowel wall, referred to as histoanatomical differences. A good correlation between histoanatomy and UHFUS of the bowel wall has been proven. In order to perform more precise and objective histoanatomical morphometrics, the main research objective of this study was to develop a compu
The erectoides-m anthocyanin-less 1 (ert-m ant1) double mutants are among the very few examples of induced double mutants in barley. From phenotypic observations of mutant plants it is known that the Ert-m gene product regulates plant architecture whereas the Ant1 gene product is involved in anthocyanin biosynthesis. We used a near-isogenic line of the cultivar Bowman, BW316 (ert-m.34), to create
The electrocardiogram (ECG) is the most widely used imaging tool helping in diagnosis and initial management of patients presenting with symptoms compatible with acute coronary syndrome. Acute ischemia affects the configuration of the QRS complexes, the ST segments and the T waves. The ECG should be read along with the clinical assessment of the patient. ST segment elevation (and ST depression in
Background: Short children born small for gestational age (SGA) are treated with growth hormone (GH) dose based on body size, but treatment may lead to high levels of IGF-I. The objective was to evaluate IGF-I titration of GH dose in contrast to current dosing strategies. Methods: In the North European Small for gestational age study (NESGAS) 92 short pre-pubertal children born SGA were randomised
The transition quadrupole moments. Q(t), of four weakly populated collective bands up to spin similar to 65h in Er-157,Er-158 have been measured to be similar to II eb demonstrating that these sequences are associated with large deformations. However, the data are inconsistent with calculated values from cranked Nilsson-Strutinsky calculations that predict the lowest energy triaxial shape to be as
