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This thesis aimed to search for epidemiological evidence supporting the associations of type 2 diabetes mellitus (T2DM) with cancer and autoimmune diseases (ADs) by analysing several Swedish national registries. T2DM shares risk factors with cancer, such as obesity, diet, stress, and physical inactivity. However, it is unclear whether the associations with several types of cancers are due to share
In Sweden mental ill-health has increased among the young, especially among young women. Our aim was to investigate the association between experience of physical violence during the past year and self rated psychological health among young men and women.
Changes in agricultural management have been identified as the most probable cause for the decline of Skylark (Alauda arvensis) populations in Europe. However, parasitic infections have not been considered as a possible factor influencing this process. Four hundred and thirty-four Skylarks from the Southern Italy and the Netherlands were screened for haemosporidian parasites (Haemosporida) using t
PURPOSE: A Swedish and Norwegian study was designed to examine health-related quality of life (HQL) in patients with head and neck cancer (head and neck) at diagnosis and during treatment and rehabilitation. The overall aim was to examine the impact on HQL at diagnosis depending on tumor location, stage, sex, and age (part I) and to describe HQL longitudinally and determine for which patients and
Moisturizing creams have beneficial effects in the treatment of dry, scaly skin, but they may induce adverse skin reactions. In a randomized double-blind study, 197 patients with atopic dermatitis were treated with one of the following: a new moisturizing cream with 20% glycerin, its cream base without glycerin as placebo, or a cream with 4% urea and 4% sodium chloride. The patients were asked to
The decays of the high angular momentum, high spin F-4(0) states of the electron configuration 3s3p3d in aluminium-like ions (with three electrons outside a closed shell) have been identified in delayed spectra of foil excited Ti, Fe and Ni ion beams. The line identifications were aided by HXR, MCHF, and MCDF calculations and are corroborated by lifetime measurements which demonstrate the differen
Objectives: To assess the risk of lymphoproliferative disease or other malignancy (standardised incidence ratios (SIRs)), in patients with primary Sjogren's syndrome according to the American-European Consensus Criteria (AECC), compared with patients with sicca syndrome (non-AECC) and the background population. To identify predictors of malignancy and describe lymphoma types and survival probabili
The transition from a-helix to random coil of the titrating polyamino acid Co-poly-L-(lysine, phenylalanine), (p-(Lys,Phe)), has been investigated as a function of pH and ionic strength in aqueous solution and at the air water interface by means of circular dichroism (CD) spectroscopy and the Langmuir surface film balance technique. The results strongly suggest that the helix-coil transition for p
We have performed scanning tunnelling microscopy (STM) measurements of thin films of Co and CoPt alloys on Pt(111). In contrast to the interpretation of an earlier low energy electron diffraction investigation by Tsay and Shern [Surf. Sci. 396 (1998) 313] we find that the structure observed upon annealing a Pt(111) sample with a 2 ML (monolayer, ML) thick film of Co does not consist of a rotated C
Popular Abstract in Swedish För att kunna simulera de fysikaliska fenomen som pågår i förbränning, krävs även en beskrivning av den kinetik som ingår i förbränningsprocessen. För detta ändamål utvecklas kinetiska modeller. En kinetisk modell är en lista med kemiska reaktioner och reaktionshastighetsparametrar. Modellernas tillämpningsområde begränsas av de valideringsfall och de fysikaliska parameThe simulation of physical phenomena occurring in chemical reactors requires the description of the kinetics involved in the underlying combustion process. Kinetic models are developed for this purpose. A software package, BlueBellMouse, has been developed to facilitate a deeper automatization and ease of simulation, reduction and optimization of kinetic models. A kinetic model is made of a list o
AIMS: Increased or altered activities of cysteine proteases have been implicated in serious human disorders such as cancer, rheumatoid arthritis, sepsis, and osteoporosis. To improve the current knowledge of the regulatory role of a major mammalian cysteine protease inhibitor, cystatin C, in such disease processes, a cystatin C deficient mouse was generated and characterized. METHODS: The mouse cy
Background: Smoking is the major risk factor for cardiac events in younger women and is most common in groups with the least favourable socioeconomic circumstances. Objective: To assess to what extent geographical differences in the female incidence of myocardial infarction in the city of Malmo in Sweden can be accounted for by smoking and to what extent intra-urban variances of smoking are relate
Aims To describe guideline adherence and application of different stroke risk strati. cation schemes regarding antithrombotic therapy in real-life atrial. brillation (AF) patients and to assess which factors influence antithrombotic management decisions. Methods and results The Euro Heart Survey enrolled 5333 AF patients in 35 countries, in 2003 and 2004. Prescription of antithrombotic drugs, espe
Optimizing pharmacokinetic/pharmacodynamic indices of antibiotics to obtain clinical and microbiological efficacy is essential, but dosing regimens must also be tailored to minimize the risk for emergence of resistance. The aim of the present study was to investigate whether certain concentrations of benzylpenicillin are critical for the selection of resistant subpopulations. A mixed culture of St
OBJECTIVE. The goal was to examine whether being a victim of bullying was associated with medicine use, taking into account the increased prevalence of physical and psychological symptoms. METHODS. The study population included all students in grades 5, 7, and 9 (mean ages: 11.6, 13.6, and 15.6 years, respectively) in a random sample of schools in Denmark (participation rate: 88.5%; N = 5205). The
The aim of this work is to generate detailed and simplified kinetic models for the oxidation of the Primary Reference Fuels (PRF) n-heptane, iso-octane and their mixtures, with low numbers of species and reactions. These mechanisms are consistent in terms of the choice of kinetic parameters for the different reaction classes. The further aim is to validate the kinetic models for a wide range of di
Current e-learning systems are increasing their importance in higher education. However, the state of the art of e-learning applications, besides the state of the practice, does not achieve the level of interactivity that current learning theories advocate. In this paper, the possibility of enhancing e-learning systems to achieve deep learning has been studied by replicating an experiment in which
A search for a narrow baryonic resonance decaying to K(s)(0)p or K-s(0)(p) over bar is carried out in deep inelastic ep scattering with the H1 detector at HERA. ss Such a resonance could be a strange pentaquark Theta(+), evidence for which has been reported by several experiments. The K(s)(0)p and K-s(0)(p) over bar invariant ss mass distributions presented here do not show any significant peak in
The aim of the present study was to examine the influence of pregnancy on deterioration of retinopathy in patients with Type 1 diabetes mellitus. Sixty-five pregnant Type 1 diabetic women attending the University Hospital in Lund were studied retrospectively. The degree of retinopathy, and levels of HbA1c and blood pressure 12 months before, during, and 6 months after pregnancy were compared of th
