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Robotic systems often face execution failures due to unexpected obstacles, sensor errors, or environmental changes. Traditional failure recovery methods rely on predefined strategies or human intervention, making them less adaptable. This paper presents a unified failure recovery framework that combines Vision-Language Models (VLMs), a reactive planner, and Behavior Trees (BTs) to enable real-time
Robotic systems often face execution failures due to unexpected obstacles, sensor errors, or environmental changes. Traditional failure recovery methods rely on predefined strategies or human intervention, making them less adaptable. This paper presents a unified failure recovery framework that combines Vision-Language Models (VLMs), a reactive planner, and Behavior Trees (BTs) to enable real-time
Transfusion-related acute lung injury (TRALI) is a leading cause of transfusion-related mortality. Though the precise mechanism is not fully understood, a 2-hit model is widely accepted, involving both a predisposing patient condition and the transfusion itself. Mitochondrial damage-associated molecular patterns (mtDAMPs), such as mitochondrial DNA (mtDNA) and N-formylated peptides (NFPs), are ele
The androgen receptor (AR) is a critical driver of prostate cancer (PCa). Here, to study regulators of AR protein levels and oncogenic activity, we developed a live-cell quantitative endogenous AR fluorescent reporter. Leveraging this AR reporter, we performed genome-scale CRISPRi flow cytometry sorting screens to systematically identify genes that modulate AR protein levels. We identified and val
Background: Rehabilitation after Knee Replacement (KR) surgery often entails an extensive rehabilitation in primary care but evidence-based high-quality guidelines are lacking. There is also a knowledge gap regarding current rehabilitation modalities applied in primary care in Sweden. This study aimed to (I) describe rehabilitation in primary care after KR and (II) explore phys-iotherapists’ perce
Indigenous archaeology and archaeology of Indigeneity are paramount in the contemporary world. We certainly need more of it across the archaeological scale and across the archaeological globe. Archaeology’s unhealthy attachment to colonialism, colonial administration and imperialism keeps on affecting our discipline on all levels. It is therefore encouraging to read Felix Acuto’s call for an engag
A central challenge in water electrolysis lies with the oxygen evolution reaction (OER) where the formation of molecular oxygen (O2) is hindered by the constraint of angular momentum conservation. While the reactants OH− or H2O are diamagnetic (DM), the O2 product has a paramagnetic (PM) triplet ground state, requiring a change in spin configuration when being formed. This constraint has prompted
BACKGROUND AND OBJECTIVE: A post hoc analysis of TITAN evaluated the clinical benefit of apalutamide plus androgen-deprivation therapy (ADT) versus ADT alone in metastatic hormone-sensitive prostate cancer (mHSPC) with high disease burden. METHODS: Patients were assessed in subgroups of those with four to fewer than ten, ten to <20, or ≥20 bone metastases; with lung but not liver metastases; and w
Introduction: The optimal timing for distal radial fracture fixation remains controversial. Most previous studies have dichotomized timing into early or delayed categories, potentially obscuring the true effect of delay. This study investigated surgical timing as a continuous variable to determine its influence on radiographic alignment. Methods: In a retrospective multicentre cohort study, we rev
Bullying is increasingly understood as a group-based phenomenon in which bystanders play a critical role, yet little is known about how witnessing bullying affects bystanders’ self-esteem and academic motivation. The aim of this study was to explore adolescents’ perspectives on how witnessing bullying in school may be linked to their self-esteem and academic motivation. This qualitative study expl
Background: Women who have undergone cervical conization may still experience subsequent pregnancies and delivery. However, it remains unknown whether pregnancy, associated with immune tolerance, might increase the risk of subsequent cervical lesions. This study aims to address this knowledge gap by utilizing the nationwide Swedish registers. Methods: A total of 60,895 women diagnosed with cervica
Intro: Population-based studies predominantly focused on carcinoma of the parotid gland (CPG) are rare. The study aims were to analyze the incidence of CPG and to assess treatment outcomes in relation to histopathology, preoperative diagnosis and adjuvant radiotherapy. Methods: A retrospective analysis was conducted on data from the Swedish Head and Neck Cancer Register (SweHNCR), including 1,018
Background: Diffuse large B-cell lymphoma (DLBCL) exhibits immunological heterogeneity that influences outcomes of immunochemotherapy, with CD8+ T cells playing a critical role in patient prognosis. Methods: We integrated single-cell and bulk transcriptome data to establish a CD8⁺ T cell–associated prognostic signature. Single-cell RNA sequencing data from 29 samples (28 individuals), including DL
Background and purpose — Patient-specific instrumentation (PSI) in total knee arthroplasty (TKA) aims to improve implant alignment and clinical outcomes, but its effectiveness remains uncertain. We aimed to compare whether PSI was superior to conventional instrumentation (CVI) in TKA. The primary outcome was the Oxford Knee Score (OKS) at 2 years with assessments of additional clinical outcomes up
The isolation, identification and structure of the spalt gene is described. This novel homeotic gene of Drosophila is required for the establishment of the posterior-most head and the anterior-most tail segments of the embryo. It encodes a small mRNA of 0.8 kb which is under the control of over 15 kb of upstream sequences as indicated by the phenotype of transformed embryos. The putative spalt pro
