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Different classes of non-coding RNAs, including microRNAs, have recently been implicated in the process of tumourigenesis. In this study, we examined the expression and putative functions of a novel class of non-coding RNAs known as transcribed ultraconserved regions (T-UCRs) in neuroblastoma. Genome-wide expression pro. ling revealed correlations between specific T-UCR expression levels and impor

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Bygg- och anläggningsbranschen har störst påverkan på klimatet som bransch. Sverige har som mål att nå noll nettoutsläpp av växthusgaser innan 2045 och masshanteringen är en stor bidragande faktor till den stora klimatpåverkan. Stora mängder massor hanteras och transporteras, där en liten procent återanvänds. Det föreslås därför i branschen att cirkuläritet ska införas för att skapa en mer hållbarThe infrastructure industry, the soil management in particular, has a significant impact on the climate. The great mass movement that occurs in an infrastructure project needs management and transport and in addition there is only a small percentage that is reused. A more circular approach has been suggested to be applied in the industry. A case study was performed of three infrastructure projects

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This purpose of this paper is to explain the long and short run development of the Net International Investment Position (NIIP) using age structure data. Following the financial globalization, the development of the NIIP has diverged from the path of accumulated current account flows. A subsequent consequence is that despite sustained current account surpluses, NIIPs of small developed countries r

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Models of physical systems are often expressed as a system of mathematical expressions derived from first principles. However some of the relationships present in a model are more conveniently expressed as a table, i.e. for certain values of independent variables the values of dependent variables are known. This imposes a limitation on the optimization software to be used, since optimization softw

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En vegetationskarta och en digital höjdmodell har gjorts över ett 54 km2 stort område beläget på Svalbards västkust, vid Isfjorden. Vegetationskartan är baserad på flygbilder och en undersökning gjord i fält under juli månad 1994. Systemet som användes vid klassificeringen av de olika vegetationstyperna är utarbetad av Elven et al. (1990) för en liknande studie i Gipsdalen på Svalbard. Vår vegetatA vegetation map and a Digital Elevation Model has been generated over a 54 km2 area situated at the western coast of Svalbard, at the Isfjorden fiord. The map is based on aerial photographs and a field survey made during the summer of 1994. The classification system used is described by Elven et alia (1990), for a similar study in Gipsdalen in the inner part of Isfjorden. The classification of th

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This thesis is devoted to understand the relationships between the European Union (EU) and Russian Federation (RF). The study is concentrated on the fields of energy (Oil and Gas) in their strategic partnership. The events during the last century in the global energy markets have put the European Union face to face with new challenges. Obviously, it is claimed that growth dependency on Russian ene

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Ocean acidification, caused by the increased uptake of anthropogenic CO2, describes a change in the ocean’s carbonate chemistry. While its chemical processes are well understood, less is known about its biological and subsequently socio-economic consequences. However, there is evidence that marine organisms will be adversely affected by a decrease in pH and carbonate saturation levels. Fishery is

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Global problems such as atmospheric change, acid rain, and water pollution in surface and subsurface environments dominate discussions of world environmental problems. In this thesis the roles of hydrologic processes and hydrogeochemical processes are investigated through development, modification, and application of models for addressing point and non-point source contamination of water. The move

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AbstractOBJECTIVE. To test the hypothesis that exposure to thermal-degradation products of polyurethane (PUR), particularly isocyanates, induced nasal inflammation.METHODS. Thirty-eight workers -14 with a history of work-related nasal symptoms (WRS/Nose), and 15 referents without such history - exposed to sprayed and heated PUR glue, were studied with regard to biomarkers of isocyanate exposure [4

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Smooth muscle is a slow and economical muscle with a large variability in contractile properties. This review describes results regarding the relation between expression of myosin isoforms and the contraction of smooth muscle. The focus of the review is on studies of the organised contractile system in the smooth muscle tissue. The role of the myosin heavy chain variants formed by alternative spli

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Motivation: With the increasing number of gene expression databases, the need for more powerful analysis and visualization tools is growing. Many techniques have successfully been applied to unravel latent similarities among genes and/or experiments. Most of the current systems for microarray data analysis use statistical methods, hierarchical clustering, self-organizing maps, support vector machi

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A search for non-resonant Higgs boson pair production, as predicted by the Standard Model, is presented, where one of the Higgs bosons decays via the H→bb channel and the other via one of the H→WW⁎/ZZ⁎/ττ channels. The analysis selection requires events to have at least two b-tagged jets and exactly two leptons (electrons or muons) with opposite electric charge in the final state. Candidate events

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There is a growing interest in the development of functional ingredients, including those with high indigestible carbohydrate content. Unripe plantain flour (UPF) is a source of indigestible carbohydrates, type II resistant starch (RS) in particular. A major drawback of UPF, however, is that its RS content decreases sharply after wet heat treatment. Here, we explore the possibility of preparing an

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This contribution reviews theory, algorithms, and validation results for system identification of continuous-time state-space models from finite input- output sequences. The algorithms developed are autoregressive methods, methods of subspace-based model identification and stochastic realization adapted to the continuous-time context. The resulting model can be decomposed into an input-output mode

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Mentometrar (”clickers”) är ett verktyg som kan användas för att göra snabba utvärderingar av studenters kunskap och förståelse under t.ex. en föreläsning (s.k. classroom assessment), och studier har visat att de förbättrar både lärande och uppmärksamhet (Keough 2012). Genom sådana formativa utvärderingar får både studenter och lärare omedelbar återkoppling som kan hjälpa till att identifiera områ

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Background. Significant facilitators and barriers to organ donation and transplantation remain in the general public and even in health professionals. Negative attitudes of HPs have been identified as the most significant barrier to actual ODT. The purpose of this paper was hence to investigate to what extent HPs (physicians and nurses) experience such facilitators and barriers in ODT and to what