Filtyp
Identification of metabolites in non-targeted metabolomics continues to be a bottleneck in metabolomics studies in large human cohorts. Unidentified metabolites frequently emerge in the results of association studies linking metabolite levels to, for example, clinical phenotypes. For further analyses these unknown metabolites must be identified. Current approaches utilize chemical information, suc
Aims. The aim of this paper is to explore and map the age and abundance structure of the stars in the nearby Galactic disk. Methods. We have conducted a high-resolution spectroscopic study of 714 F and G dwarf and subgiant stars in the Solar neighbourhood. The star sample has been kinematically selected to trace the Galactic thin and thick disks to their extremes, the metal-rich stellar halo, sub-
The efficacy of integrating open access geospatial data to produce habitat suitability maps for the corn bunting (Miliaria calandra) was investigated. Landsat Enhanced Thematic Mapper Plus (ETM+), Shuttle Radar Topography Mission (SRTM) and Corine (Coordination of Information on the Environment) land cover data for the year 2000 (CLC2000) were processed to extract explanatory variables and divided
BACKGROUND: Situational needs of health care facilities inform the optimal allocation of resources and quality improvement efforts. This study examines surgical care delivery metrics at a tertiary care institution in Liberia. METHODS: We retrospectively reviewed operative and ward logbooks from January 1 to December 31, 2012. Data parameters included patients' age, diagnosis, procedure, mortality,
BACKGROUND: Studies in West Africa and elsewhere have suggested that Bacillus Calmette-Guerin (BCG) vaccine given at birth is beneficial for child survival. It is possible that this effect is mediated partly through an effect on malaria, a hypothesis supported by animal studies. We investigated whether revaccination with BCG at 19 months of age reduced morbidity from malaria. METHOD: In the capita
Popular Abstract in Swedish I avhandlingen presenteras nya teoretiska och experimentella metoder för att analysera spridning av elektromagnetiska vågor, framförallt med fokus på antenner och trådlös kommunikation. Oavsett det handlar om radio- och TV-sändningar, mobiltelefoni, trådlösa datornätverk, eller radar, så är antenner oumbärliga; de är nämligen länken mellan de elektromagnetiska vågorna oSum rules and physical limitations within electromagnetic theory and antenna theory have received significant attention in the last few years. However, the derivations are often relying on application specific and sometimes unsupported assumptions, and therefore a mathematically rigorous and generally applicable approach seems timely. Such an approach is presented in this thesis, along with exampl
Ulcerated diabetic foot is a complex problem. Ischaemia, neuropathy and infection are the three pathological components that lead to diabetic foot complications, and they frequently occur together as an aetiologic triad. Neuropathy and ischaemia are the initiating factors, most often together as neuroischaemia, whereas infection is mostly a consequence. The role of peripheral arterial disease in d
Studien syftar till att undersöka materialistiska attityder och dess samband till problematiskt självrapporterat shoppingbeteende samt kartlägga hur shoppingbeteendet ser ut bland Lunds studenter. Undersökningsgruppen är 100 studenter från Lunds tekniska högskola och Ekonomihögskolan. Hypoteserna är: högre materialistiska värderingar predicerar mer självrapporterat shoppingbeteende och högre mater
När organisationer tvingas förändras för att klara av kraven i omvärlden, ställs det ofta krav på att organisationsmedlemmarna ska förändra sitt arbetssätt eller tillägna sig nya kunskaper och förmågor. Det finns dock en risk för att hinder, av olika slag, hindrar medarbetarnas lärande från att nå upp till de önskade utfallen. Fokus för denna studie är ett produktionsföretag inom livsmedelsbransch
Den aktuella studien undersökte hur barn omkring perioden för ordförrådsspurten uppmärksammar generell form samt signifikanta detaljer vid visuell objektigenkänning, både avseende nya bild-ordpar samt för redan etablerade bild-ordpar. Event-Related Potentials (ERPs) registrerades i syfte att analysera hur barn på en neural nivå reagerar på kongruenta och inkongruenta presentationer av bild-ordpar,The present study investigated how children around the time of the vocabulary spurt attend to overall shape and significant detail in visual object recognition, regarding both novel picture-word pairs as well as already established picture-word pairs. Event-Related Potentials (ERPs) were recorded in order to analyze how children on a neural level respond to congruent and incongruent presentations
Background and aim: Generic drugs contain the same active ingredients as brand- name drugs, with the advantage of much lower costs. The aim of this thesis was to contribute new knowledge to the ongoing debate on the safety of generic antiseizure drug (ASD) substitutions. There was a particular emphasis on the pharmacokinetic and clinical outcomes.Methods: In papers I and II, a prospective naturali
Amplification of fibroblast growth factor receptor 1 (FGFR1) in non-small cell lung cancer (NSCLC) has been considered as an actionable drug target. However, pan-FGFR tyrosine kinase inhibitors did not demonstrate convincing clinical efficacy in FGFR1-amplified NSCLC patients. This study aimed to characterise the molecular context of FGFR1 expression and to define biomarkers predictive of FGFR1 in
A number of large-scale fire experiments with detailed quantitative analysis of polycyclic aromatic hydrocarbon (PAH) including PAH congener distribution have been conducted by SP. This data is reviewed here and is further assessed with regard to toxicity applying a Toxic Equivalency Factor (TEF) model for estimation of cancer potential. The PAH yield data from the large-scale fire experiments is
Laminar burning velocity S L at elevated temperature T u and its temperature dependence coefficient α in SL/S0L = (Tu T0u)α are important parameters for industrial applications. However, experimental systems with high unburned gas temperatures may encounter pre-dissociation, leading to significant data scattering in the measurements. To negate this, the present work proposes a projection procedure
Background: Pay-for-performance (P4P) has been widely used in healthcare, but there are few experiences of hospital-based P4P at scale. The evidence of impact from these has been mixed, and there has been increased recognition of the importance of different contexts, designs, incentives and other factors. In 2014, the Lebanese Ministry of Public Health integrated a P4P model for determining hospit
This study aimed to investigate the influence of stroke lesions in predefined highly interconnected (rich-club) brain regions on functional outcome post-stroke, determine their spatial specificity and explore the effects of biological sex on their relevance. We analyzed MRI data recorded at index stroke and ~3-months modified Rankin Scale (mRS) data from patients with acute ischemic stroke enrolle
Socionomutbildningen har under de senaste fyra decennierna expanderat kraftigt men analyser av vad denna utveckling innebär för socionomfältet är få, ingen vetenskaplig text uppmärksammar specifikt kompetensprofilen hos den undervisande personalen. Syftet med denna artikel är att undersöka utbildningens kvalitet med fokus på kompetensprofilen bland undervisande personal på socionomutbildningar i S
