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Background Brain metastases are a common complication in cancer, particularly in patients with breast cancer, lung cancer, and melanoma, and are associated with poor prognosis. Understanding the spatial organization of tumor and immune cells is critical for uncovering the mechanisms of metastasis. Spatial transcriptomics technologies now allow gene expression profiling while preserving tissue arch
This study investigates the application of Bayesian methods in Media Mix Modeling (MMM) and compares their performance against more traditional regression models. We develop multiple MMM's to quantify the impact of media and non-media variables on a company's performance, including: (1) a Bayesian regression model incorporating prior knowledge and posterior inference, and (2) simpler regre
This research examines the consequences of disciplinary time, for the workers at Foxconn in China, based on the monograph “Dying for an iPhone” and poetry by former Foxconn worker Xu Lizhi. Grounded in Fouacauldin disciplinary theory, this research will exhibit what the apparatus of discipline looks like at Foxconn. It will focus on how physical and mental pain occurs when capitalism uses time as
Popular Abstract in Swedish Stora framsteg har gjort det möjligt att, med dagens teknik, inte bara visualisera enskilda atomer, utan även utföra olika typer av operationer och manipulationer på atomskalan med stor precision rent experimentellt. Detta har möjliggjort tillverkning av komplexa nanostrukturer genom montering av komponenter av nanostorlek till större sammansatta system, vilket i sin tuNanowires constitute one of the fundamental building blocks in assembled nanodevices. Due to the high surface to volume ratio, the fraction of surface atoms is not negligible for nanosized elements. Because of the reduced coordination of surface atoms, the physical properties deviate from those of the bulk, which influences the overall physical properties of nanostructures. Consequently, this prov
Tropical forest soils are a significant source for N2O and NO. Current estimates of N2O and NO emissions areuncertain due to the limited number of fieldmeasurements and model input data. Furthermore, considerable spatialand temporal variability exists due to variation of soil properties, vegetation characteristics and meteorology.Weused a process-based model (ForestDNDC-tropica) to estimate N2O an
The scalability of computational applications on current and next-generation supercomputers is increasingly limited by the cost of inter-process communication. We implement non-blocking asynchronous communication in the High-Order Methods Modeling Environment for the time integration of the hydrostatic fluid equations using both the spectral-element and discontinuous Galerkin methods. This allows
PurposeThe paper aims to examine some economical, political and health system indicators on the transmission of the COVID-19 transmission within the national system. The main objective is to investigate what are the most effective indicators which have led to the declared numbers by countries.Design/methodology/approachThis study combined multiple sets of data to describe best the economical statu
Introduction: The first-line evidence-based treatment for chronic pain is multidisciplinary treatment involving pain-focused CBT. Studies have shown that changes in psychological flexibility (PF) during pain-focused CBT positively mediatesoutcomes, even when the treatment does not specifically target PF. While CBT and PF-based treatments for chronic pain yield small to moderate, but clinically mea
Childhood stunting (height‑for‑age z‑score < −2) remains a global public health challenge, and national averages often mask subnational clustering and spatial heterogeneity of underlying determinants. Across four papers, this thesis integrates geocoded household data with gridded geospatial surfaces from nationally representative survey data to map stunting hotspots, quantify spatially varying and
We present an innovative hydrogeophysical approach for non-invasive quantification of the unsaturated water flow. For the water content measurements, we apply the Magnetic Resonance Sounding (MRS) method in the time-lapse mode. For inversion of MRS measurements, we approximate the subsurface by a horizontally stratified media. Laterally, the MRS estimated water content is averaged over the area be
We report on the measurement of inclusive, non-prompt, and prompt J/ψ-hadron correlations by the ALICE Collaboration at the CERN Large Hadron Collider in pp collisions at a center-of-mass energy of 13 TeV. The correlations are studied at midrapidity (|y| < 0.9) in the transverse momentum ranges pT< 40 GeV/c for the J/ψ and 0.15 < pT< 10 GeV/c and |η| < 0.9 for the associated hadrons. The measureme
This paper presents PyEtSimul, an open-source Python-based framework for simulating video-based eye trackers by generating synthetic eye features through geometric modeling. The framework allows flexible positioning of eyes, cameras, and light sources in 3D space, with controlled variation of eye anatomical features and camera properties. PyEtSimul generalizes corneal modeling by representing the
The Earth’s magnetic field (or geomagnetic field) has been measured for hundreds of years, starting with maritime observations from logbooks for navigation purposes to present day real-time recording by satellites. From these records, the geomagnetic field variation throughout recent time is well-understood. In order to study longer term field variations (on the scale of hundreds to thousands of y
Blodet bär med sig syre och näringsämnen som är vitala för vävnadens överlevnad, och därför är karakterisering av hjärnans blodförsörjning av stor betydelse. Blodflödet i kapillärerna kallas för perfusion. Vid MRI-baserad perfusionsmätning i hjärnan utnyttjas ofta signalförändringar orsakade av ett spårämne i blodet. Spårämnet kan antingen skapas internt genom märkning av det arteriella inflödet aDiffusion and perfusion MRI are valuable methods for investigating the microstructure and viability of tissue. One pure diffusion study was included in this thesis, with the purpose of studying microstructure and carrying out size estimations with the q-space diffusion imaging method. This is a method that has predominantly been explored with NMR spectrometers. In our study, a biological phantom c
In this study we ask how a range of environmental sustainability adjustments that consumers find it easy to adopt affect the carbon footprint of their food consumption. The study is based on information about real purchases of food products and responses to a questionnaire about the various sustainability adjustments that the study participants apply and their concern about climate change. Based o
