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This is the Replicated Computational Results (RCR) Report for the article “Testing Abstractions for Cyber-Physical Control Systems.” The article empirically studies how substituting different components in Cyber-Physical Systems (CPSs) testing with simulators impacts the fault-exposition. This RCR report describes the artefacts used in the article, how to use the testing setups used in the article
BACKGROUND: Previous research has identified a need for relevant evidence-based clinical guidelines in primary care physiotherapy. However, an essential first step is to identify the most prevalent diagnoses among patients seeking physiotherapy. Thus, this study aims to (I) identify the most prevalent musculoskeletal diagnoses and, (II) describe physiotherapy utilization and patient characteristic
The evolutionary transition to eusociality in the solitary ancestors of social insects, like ants, termites, wasps and bees, may have been initiated by an environmental induction of group living. Plasticity in social behaviour in response to the environment can be found in facultatively social insects. However, it is currently unknown which environmental cues trigger the individual decision of an
Traceability is a transparent quality index in almost every supply chain. Especially when it comes to highly perishable products, such as dairy, the need for an effective traceability system is unavoidable due to increased fraudulent products, adulteration, excessive additives, and toxic substances. The dairy industry requires an effective traceability system that ensures visibility and transparen
INTRODUCTION: Automated cerebrospinal fluid (CSF) biomarker assays have largely replaced manual immunoassays for measuring amyloid pathology in CSF. We refitted and validated the ABIDE model, predicting progression from mild cognitive impairment (MCI) to dementia, with CSF measurements from the automated Elecsys platform. METHODS: We included 2413 MCI participants (998 [41%] amyloid-positive) from
The process that generates the different types of highly differentiated cells in the immune system from hematopoietic stem cells involves not only the acquisition of lineage-specific features, but also the permanent repression of alternative developmental programs and the preservation of lineage identity. The well-charted developmental trajectory of early B-cell development, in combination with ab
In this study we investigate day-care centres as a form of community-based support designed to facilitate ageing in place for individuals with dementia, with the goal of delaying or preventing their transition to institutional care. Day-care centres provide structured activities designed to alleviate loneliness and isolation, affirm personal identity, and offer respite for family caregivers. In Sw
Heterogeneous catalysts based on Single Atom Alloys (SAA) play a significant role in numerous technical processes. The fundamental working principles of these systems, however, remain poorly understood, especially the aspects related to the nanoscopic nature of bimetallic particles and the associated structure-reactivity relationships. In this study, we developed for the first time well-defined SA
Water is essential for life. This is particularly true for terrestrial insects, whose small size and high surface-area-to-volume ratios render them especially susceptible to dehydration. To overcome this challenge, insects have evolved sophisticated physiological mechanisms and behavioral strategies to maintain internal ion and water balance despite fluctuating environmental conditions. This chapt
Introduction: Child abuse is a global public health problem. It poses a threat to both physical and psychosocial well-being, resulting in serious consequences for the child, the family, and society. Radiographers are in a unique position to identify children at risk. In clinical practice, they may observe unusual interactions between children and their caregivers during radiographic procedures or
Many plant invasions establish from only a few individuals and exhibit clonal spread, providing an opportunity to examine the genomic mechanisms that underlie the success of particularly aggressive individuals. One of the world’s most invasive species, the Japanese knotweed complex, is well suited for such investigations. Simultaneously developing ecological and genomics work in the native and int
Play is a quintessential human behaviour, underpinned by motor organisation and fundamental for learning and development. However, the motor patterns underlying play have not been computationally characterised in children with autism, despite known play pattern differences, including reduced social and pretend play. Recent evidence of fundamental neuromotor disruption in autism suggests neuromotorPlay is a quintessential human behaviour, underpinned by motor organisation and fundamental for learning and development. However, the motor patterns underlying play have not been computationally characterised in children with autism, despite known play pattern differences, including reduced social and pretend play. Recent evidence of fundamental neuromotor disruption in autism suggests neuromotor
Implementing the Internet of Things (IoT) into business models has become an influential catalyst, supporting novel revenue generation, improved operational efficiencies, and competitive dominance. Still, its implementation has been challenged by barriers to technological, organizational, and societal dimensions. The current study utilizes the Fuzzy Decision-Making Trial and Evaluation Laboratory
The in vivo fate of mesenchymal stromal cells (MSCs), including their clearance, interaction with host tissues, and persistence, remains incompletely understood following systemic or local clinical administration to patients. Although immune-mediated clearance mechanisms, such as triggering of the instant blood-mediated inflammatory reaction, activation of coagulation and complement pathways, apop
Background and purpose — Patient-specific instrumentation (PSI) in total knee arthroplasty (TKA) aims to improve implant alignment and clinical outcomes, but its effectiveness remains uncertain. We aimed to compare whether PSI was superior to conventional instrumentation (CVI) in TKA. The primary outcome was the Oxford Knee Score (OKS) at 2 years with assessments of additional clinical outcomes up
Aggressive tumours are defined by microenvironmental stress adaptation and metabolic reprogramming. Within this niche, lipid droplet accumulation has emerged as a key strategy to buffer toxic lipids and suppress ferroptosis. Lipid droplet formation can occur via de novo lipogenesis or extracellular lipid-scavenging. However, how tumour cells coordinate these processes remains poorly understood. He
In the face of climate change, today’s young people need to balance the challenges of being active and maintaining mental health. This study investigated climate resilience, meaning patterns of climate engagement and mental health among adolescents. Using latent profile analysis, we identified three profiles in a sample of N=603 Swedish adolescents: climate-resilient (17%, active and not impaired)
Protein deletions are frequent among both disease-causing and tolerated variants. Several mechanisms at the DNA, RNA and protein levels can lead to deletions. Many deletions are misclassified in the literature and databases, especially when the mRNA is degraded by the cellular quality-control mechanism. We developed a novel predictor for sequence retaining protein deletions, i.e., variants that do
Understanding variation in survival and reproduction is key for conservation and management of bird populations. By compiling and analysing data on hatching success (i.e. proportion of nests with at least one hatched egg) from Common Eider Somateria m. mollissima, Velvet Scoter Melanitta fusca and Red-breasted Merganser Mergus serrator, all breeding on a single island in the Baltic Sea, we demonst
