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Using heuristics to glide an Airbus A320 following all-engine failure in cruise : A simulator-based experimental study

Performing a controlled glide of an Airbus A320 following an all-engine failure at cruising altitude is a highly demanding task for pilots. This study investigates whether judgement heuristics can enhance pilot performance in managing this scenario. While the existing ALL ENG FAIL Airbus procedure provides valid guidance, it offers disconnected navigational inputs to the pilots. This simulator-bas

Financial KPI extraction using Large Language Models

Extracting financial Key Performance Indicators from annual reports is one of many manual tasks in the banking sector. This can be automated with Machine Learning techniques such as Question Answering, Named Entity Recognition, Entity Relation, Text-to-Sql, or Retrieval Augmented Generation. In this thesis, different models performances are evaluated when extracting KPIs from annual reports, both

“Who killed Laura Palmer?” – Kvinnlig representation, trauma och blick i David Lynchs Twin Peaks

This essay examines the film character Laura Palmer from the television series Twin Peaks and the feature film Fire Walk With Me. The purpose of this essay is to discuss how the character Laura Palmer differs between the series and the film. How does she change from being an object to a subject, and how do we see a change between the series and the film? This is done in dialogue with Laura Mulvey&

Polygenic risk score-guided personalized osteoporosis screening : a population-based study

Background: Despite robust evidence that genetic factors substantially influence both osteoporosis development and fracture risk, current screening guidelines fail to incorporate genetic factors into risk-assessment protocols. This study aims to determine personalized screening ages for osteoporosis based on polygenic risk score (PRS). Methods: This prospective cohort study utilized data from 223,

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Pretrained language models are integral part of AI applications, but their high computational cost for training limits accessibility. Initiatives such as Bloom and StarCoder aim to democratize access to pretrained models for collaborative community development. Despite these efforts, such models encounter challenges such as limited multilingual capabilities, risks of catastrophic forgetting during

Lecanora hybocarpa and similar European species

The lichen genus Lecanora is one of the largest genera of lichenized fungi. The core part of the genus is the L. subfusca group and within this group, Lecanora hybocarpa (Tuck.) Brodo, initially described from North America and thought to be endemic, has been reported from several European countries. However, the identity of these European specimens has been increasingly questioned. This study aim

Laboratory evaluation of ARMIE, a portable SPS30-based low-cost sensor node for PM2.5 monitoring

Background: Low-cost particulate matter sensors have enabled new opportunities for exposure monitoring but require evaluation before application in epidemiological studies. This study assessed the performance of the SPS30 sensor integrated into the ARMIE portable monitoring sensor-node under controlled laboratory conditions. Methods: Sensors were co-located with two comparison instruments—the opti

Improved sex-specific cardiovascular risk prediction with multi-omics data in people with type 2 diabetes

Background: To evaluate whether integrating proteomics, metabolomics, and a cardiovascular disease specific polygenic risk score (CVD-PRS) in the SCORE2-Diabetes model improves sex-specific 10-year prediction of major adverse cardiovascular events (MACE) in individuals with type 2 diabetes (T2D). Methods: Genome-wide association study (GWAS), plasma proteomics (with the Olink Explore 3072 platform

Islamic educational spaces : architecture of Madrasah and Muslim educational institutions

The mosque (both as masjid or jāmiʿ) is recognized as the first Muslim educational space for formal and informal learnings, for children and adults alike. Although the mosque remained as one of the primary centers of Islamic studies in various disciplines to this day, the Muslim cities from the Middle Ages onward have witnessed the emergence of specific institutions for Islamic education. Kuttābs

Municipal governance of the sharing economy sectors: global insights

The sharing economy generates many benefits for cities and their citizens. However, it also causes numerous economic, social and environmental challenges, which are the reasons cities develop various policies and regulations. Previous research has explored municipal regulations across cities and countries but often overlooked alternative governance mechanisms. Our earlier work highlighted the need

Oscillometry findings in altered spirometry patterns and relationship to respiratory symptoms

Background Preserved ratio impaired spirometry (PRISm) and restrictive spirometry pattern (RSP) are associated with increased morbidity and mortality, but the underlying mechanisms are unclear. Impulse oscillometry (IOS) measures small airway function more sensitively than spirometry. We aim to study the prevalence of abnormal IOS findings in relation to three spirometry patterns (obstructive, PRI

Environment agnostic goal-conditioning : a study of reward-free autonomous learning

In this paper we study how transforming regular reinforcement learning environments into goal-conditioned environments can let agents learn to solve tasks autonomously and reward-free. We show that an agent can learn to solve tasks by selecting its own goals in an environment-agnostic way, at training times comparable to externally guided reinforcement learning. Our method is independent of the un

Multiomics assessment of lung adenocarcinoma subtypes defined through tumor purity-adjusted DNA methylation

BackgroundMolecular subtypes of lung adenocarcinoma (LUAD) with varying prognosis and characteristics have been proposed based on one or two-dimensional studies but are not yet implemented into clinical routine. Epigenetic modifications in cancer cells are independent of sequence variants, directly linked to gene and genome regulation, and thus provide important information to guide subclassificat

Native T1-mapping using cardiovascular magnetic resonance detects myocardium at risk during the first week following myocardial infarction in a swine model and in patients - comparison to contrast-enhanced cine steady-state free precession

Background: Myocardium at risk (MaR) can be evaluated by cardiovascular magnetic resonance (CMR) imaging using contrast-enhanced steady state free precession (CE-SSFP) in patients after ST-elevation myocardial infarction (STEMI). However, CE-SSFP utilizes gadolinium contrast, which is contraindicated in patients with severe renal insufficiency. Native T1-mapping is a non-contrast CMR method which

Longitudinal outcome prediction of prostate cancer patients on active surveillance using multiple instance learning

Purpose: To avoid over-treatment of prostate cancer patients following screening for elevated prostate-specific antigen levels, keeping patients on active surveillance has been suggested as an alternative to radical treatment. This means recurring visits for patients with low-grade cancer to monitor progression. Our aim was to develop an artificial intelligence-based model that can identify high-r

Driving circular economy : key enablers for a sustainable meat supply chain in India

In the current era, the meat supply chain plays a vital role in the food industry. The meat supply chain is experiencing significant challenges due to the increase in demand and Circular Economy (CE) challenges. In the meat supply chain, a huge waste is generated during the meat processing, and it is much needed to manage waste effectively, considering the large quantities of by-products, packagin

Fungal cellulose decomposition : Insights into decomposition strategies using spectroscopic and molecular approaches

Cellulosa är den vanligaste biopolymeren på jorden och en viktig reservoar av organiskt kol i terrestra ekosystem. I skogar kommer mycket av denna cellulosa från trä och bryts ner av saprotrofa basidiomyceter. Dessa svampar klassificeras traditionellt som vitröta eller brunröta baserat på deras sönderfallsmekanismer i lignocellulosasubstrat. Huruvida dessa funktionella kategorier förblir distinktaCellulose is the most abundant biopolymer on Earth and a major reservoir of organic carbon in terrestrial ecosystems. In forests, much of this cellulose originates from wood and is decomposed by saprotrophic basidiomycetes. These fungi are traditionally classified as white rot or brown rot species based on their decay mechanisms in lignocellulosic substrates. Whether these functional categories re

Healthcare utilization and costs in the first two years after heart failure diagnosis : an observational study by phenotype in southwestern Sweden

Aim: Assess healthcare utilization and direct costs for heart failure (HF) during the first two years post-diagnosis across HF subgroups. Methods: This retrospective population-based study included patients with HF aged 40–90 years in Region Halland. HF subgroups were defined based on echocardiographic ejection fraction, including HF with reduced ejection fraction (HFrEF), mildly reduced ejection

Interplay between AIB1 genotypes and radiotherapy in a Swedish population-based breast cancer cohort

Purpose: Host factors, including genetic factors, are underutilized in breast cancer treatment selection. This study aimed to investigate AIB1 genotypes as pharmacogenetic markers for adjuvant breast cancer treatment. The prognostic impact of three functional polymorphisms associated with altered mRNA expression rs6094752 (low expression), rs2230782 (low expression) and rs2076546 (high expression)