Sökresultat

Despite the recent clinical success of T cell checkpoint inhibition targeting the CTLA-4 and PD-1 pathways, many patients either fail to achieve objective responses or they develop resistance to therapy. In some cases, poor responses to checkpoint blockade have been linked to suboptimal CD28 costimulation and the inability to generate and maintain a productive adaptive anti-tumor immune response.

Streptococcus pyogenes (group A streptococcus) causes a variety of diseases, including acute pharyngitis, impetigo, rheumatic fever and the streptococcal toxic shock syndrome. Moreover, S. pyogenes was responsible for the classical example of a nosocomial infection, the epidemics of puerperal fever (childbed fever) that caused the death of numerous women in earlier centuries. The most extensively

The nervous system is constantly infiltrated by blood-derived sentinels known as perivascular macrophages. Their immediate precursors have not yet been identified in situ and the mechanism that governs their recruitment is mostly unknown. Here, we provide evidence that CD68 (+)GR(-) monocytes can give rise to perivascular macrophages in mice suffering from endotoxemia. After adhesion to the endoth

Disturbed haemostasis is a central finding in severe Streptococcus pyogenes infection. In particular, microthrombi are found both at the local site of infection and at distant sites. Platelets are responsible for maintaining vascular function and haemostasis. We report here that M1 protein of S. pyogenes triggers immune-mediated platelet activation and thrombus formation. M1 protein is released fr

A dry release method for fabrication of suspended nanostructures is presented. The technique has been combined with an anti-stiction treatment for fabrication of nanocantilever based nanoelectromechanical systems (NEMS). The process combines a dry release method, using a supporting layer of photoresist which is removed using oxygen ashing in a reactive ion etcher (RIE), with CHF3 plasma induced de

Recently, to reach zero emission levels, some new energy systems based on fuel cells have been developed. This paper presents a review of investigations of these systems by thermodynamics performance, mainly, energy and exergy analysis. With energy analysis, the performance of an energy conversion system cannot be effectively and accurately evaluated. But exergy analysis complements and reinforces

7 maj 2026 11:00 till 12:00 | Seminarium Research seminars with LUCSUS researchers and guests presenting their latest research. Manuel Suter, Visiting Research Fellow, School of Social Work & LUCSUSHow do researchers understand the environmental crisis, and which responses do they recommend or perceive as feasible? This talk synthesises evidence from global surveys and experiments with academic ex

https://www.sam.lu.se/evenemang/lucsus-seminar-what-researchers-think-about-environmental-crisis-and-how-respond-evidence-global - 2026-04-27

Brutal Need : Lawyers and the Welfare Rights Movement, 1960-1973 - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysi

https://rwi.lu.se/publications/brutal-need-lawyers-and-the-welfare-rights-movement-1960-1973/ - 2026-04-27

Courts and Democracy in a One-Party State: Judicial Independence in China - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice an

https://rwi.lu.se/publications/courts-and-democracy-in-a-one-party-state-judicial-independence-in-china/ - 2026-04-28

“The Politics of Sexual Health in Vietnam” - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation

https://rwi.lu.se/publications/the-politics-of-sexual-health-in-vietnam/ - 2026-04-28

The gene for an IgA-binding protein from a group A streptococcal strain was cloned and expressed in Escherichia coli. The IgA-binding protein, called protein Arp, was purified on IgA-Sepharose, allowing complete purification in a single step. Analysis of protein Arp by Western immunoblotting demonstrated a major IgA-binding band, with an apparent molecular weight of 42 kD. The purified protein was

Purpose: In patients with hemophilia B, treatment with extended half-life (EHL) recombi-nant factor IX allows for longer dosing intervals while providing equal or superior bleeding protection compared with standard half-life products. This enables flexible, individualized treatment schedules, which reduce the burden of prophylaxis and improve patient outcomes. This analysis compared the efficacy o

Menneskerettigheder presser Fort Europa - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of

https://rwi.lu.se/publications/menneskerettigheder-presser-fort-europa/ - 2026-04-28

Det är i brottmålsprocesser ovanligt att den anklagades ålder är oklar. Men när den är det så ställs stora krav på tillräckligt precisa metoder eftersom det spelar stor roll vad den anklagade bedöms ha för ålder. De svenska påföljdsbestämmelserna särbehandlar nämligen unga lagöverträdare på olika sätt beroende på ålder. Socialstyrelsen har tagit ställning till frågan huruvida tandmognadsbedömningIn criminal proceedings it is unusual that the age of the accused is unclear. But when it is, it is of utmost importance that the methods used to determine the age are sufficiently precise because the expected age of the accised is of paramount importance. The Swedish penalties provisions specifically deal with juvenile offenders in different ways depending on age. Socialstyrelsen has considered t

Memories of the transition Memories of the transition is fictive. However, it is knowledge-based speculation. Much of the story is inspired by existing proposals, emerging innovations, or research on the transformations needed to meet our climate targets. We have collected some of these imaginative seeds below so that you can understand and construct your own vision of a post-fossil society. Conte

https://www.climatefutures.lu.se/ministryofimagination - 2026-04-27

Dnr V 2022/231 2022-02-17 1 (23) Redovisning av miljöledningsarbetet 2021 Lunds universitet Enligt förordning (2009:907) om miljöledning i statliga myndigheter Del 1 Miljöledningssystemet Basfakta Antal årsarbetskrafter: 7 380 Antal kvadratmeter lokalyta: 425 828 1. Är myndigheten miljöcertifierad? Nej. 2. Hur lyder myndighetens miljöpolicy? Lunds universitets policy för hållbar utveckling, senast

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2022-02/Lunds-universitets-miljoredovisning-2021.pdf - 2026-04-28

“Water is life”. During the past decade this phrase has been used repeatedly to emphasize the importance of a number of issues surrounding water services provision including, supply, distribution, governance and political will. This research seeks to investigate the Nairobi City Water and Sewerage Company (NCWSC), a water utility in Kenya, which faces the monumental task of providing water and san

This essay examines the personifications of Death in Markus Zusak’s The Book Thief (2005), Christopher Moore’s A Dirty Job (2006) and George Pendle’s Death: A Life (2008). The personifications are analysed in terms of gender, anthropomorphism, (im)mortality, agency in conceptual death and attitude towards their occupation as Death. The personifications are also compared to previous portrayals in r