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Glaucoma is a leading cause of blindness. Current glaucoma medications work by lowering intraocular pressure (IOP), a risk factor for glaucoma, but most treatments do not directly target the pathological changes leading to increased IOP, which can manifest as medication resistance as disease progresses. To identify physiological modulators of IOP, we performed genome- and exome-wide association an

Surface hydrophobization of cellulose nanomaterials has been used in the development of nanofiller-reinforced polymer composites and formulations based on Pickering emulsions. Despite the well-known effect of hydrophobic domains on self-assembly or association of water-soluble polymer amphiphiles, very few studies have addressed the behavior of hydrophobized cellulose nanomaterials in aqueous medi

To decrease the complexity of motion-planning optimizations, a segmentation and merging strategy for maneuvers is proposed. Maneuvers that are at-the-limit of friction are of special interest since they appear in many critical situations. The segmentation pointsare used to set constraints for several smaller optimizations for parts of the full maneuver, which later are merged and compared withopti

The current enthusiasm for the circular economy (CE) offers a unique opportunity to advance the impact of research on sustainability transitions. Diverse interpretations of CE by scholars, however, produce partly opposing assessments of its potential benefits, which can hinder progress. Here, we synthesize policy-relevant lessons and research directions for a sustainable CE and identify three narr

Peak to average power (PAPR) reduction of OFDM signals is critical in order to improve power amplifier (PA) efficiency in base stations. For massive MIMO, the complexity of these methods can become a real bottleneck in implementing low power digital signal processing chains. In this work, we consider an antenna reservation technique, which uses a low complexity clipping method to reduce signal pea

Background: The aim was to review available biokinetic data, collect own experimental data, and propose an updated compartmental model for 2-[18F]FDG in the frame of the revision of the ICRP report on dose coefficients for radiopharmaceuticals used in diagnostic nuclear medicine. Methods: The compartmental model was developed based on published biokinetic data for 2-[18F]FDG. Additional data on ur

The Global Hyperorgan is an intercontinental, creative space for acoustic musicking. Existing pipe organs around the world are networked for real-time, geographicallydistant performance, with performers utilizing instruments and other input devices to collaborate musically through the voices of the pipes in each location. A pilot study was carried out in January 2021, connecting two large pipe org

IMPORTANCE: Breast cancer (BC) is the second leading cause of cancer death in women, and there is a substantial disparity in BC mortality by race, especially for early-onset BC in Black women. Many guidelines recommend starting BC screening from age 50 years; however, the current one-size-fits-all policy to start screening all women from a certain age may not be fair, equitable, or optimal.OBJECTI

We present an analysis of atmospheric transport impact on estimating CO2 fluxes using two atmospheric inversion systems (CarboScope-Regional (CSR) and Lund University Modular Inversion Algorithm (LUMIA)) over Europe in 2018. The main focus of this study is to quantify the dominant drivers of spread amid CO2 estimates derived from atmospheric tracer inversions. The Lagrangian transport models STILT

Background and Purpose: Target delineation in glioblastoma is still a matter of extensive research and debate. This guideline aims to update the existing joint European consensus on delineation of the clinical target volume (CTV) in adult glioblastoma patients. Material and Methods: The ESTRO Guidelines Committee identified 14 European experts in close interaction with the ESTRO clinical committee

An experimental approach to verify the forward scattering sum rule for periodic structures is presented. This approach allows an upper bound on the total cross section integrated over a bandwidth from a simple static problem to be found. Based on energy conservation, the optical theorem is used to construct a relation between the total cross section and the forward scattering of periodic structure

We compute the Cramér-Rao lower bounds for determination of isotropic permittivity and permeability in slabs using scattering data such as reflection and transmission coefficients. Assuming only the fundamental mode is propagating in the slab, the results are formally the same regardless if the slab is in free space, or inside a rectangular or coaxial waveguide. The bounds depend only on signal qu

High-speed communication using the copper network, originally installed for telephony, is one of the dominant Internet access techniques. Several variants of a technology referred to as digital subscriber line (xDSL) have been developed, standardized and installed during the last two decades. Essentially, xDSL achieves high rates by exploiting wide bands of the copper cable channel. The shorter th