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Poly-3-d-hydroxybutyrate (PHB) is a promising biopolymer naturally produced by several bacterial species. In the present study, the robust baker's yeast Saccharomyces cerevisiae was engineered to produce PHB from xylose, the main pentose found in lignocellulosic biomass. The PHB pathway genes from the well-characterized PHB producer Cupriavidus necator were introduced in recombinant S. cerevisiae

In this paper, we present a controller synthesis algorithm for a decentralized control problem. We consider an architecture in which there are two interconnected linear subsystems. Both controllers seek to optimize a global quadratic cost, despite having access to different subsets of the available measurements. Many special cases of this problem have previously been solved, most notably the state

The following text addresses the threats aecting the honey-bee, and which are manifesting through the unusual death rates of bee colonies. Focus is placed in reviewing the scientic knowledge that concerns the honey-bee by discussing its cognitive and ethical categories and its in uence in nature conservation, mainly centred in the EU. Results indicate that scientic knowledge plays a fundamental ro

The cepstrum of a random process is useful in many applications. The cepstrum is usually estimated from the periodogram. To reduce the mean square error (MSE) of the estimator, the periodogram may be smoothed with a kernel function. We present an explicit expression for a kernel function which is approximatively MSE optimal for cepstrum estimation. A penalty term has to be added to the minimizatio

During the last several decades, improvements in diagnostic skills and in the treatment of children with cancer have substantially increased the number of long term survivors of childhood cancer. Treatment of children with cytostatic drugs is known to create a range of late adverse effects. Among these are damage to certain structures of the inner ear and hearing impairment. In children, a hearing

We demonstrate that freeing a single-atom thick layer of hexagonal boron nitride (h-BN) from tight chemical bonding to a Ni(111) thin film grown on a W(110) substrate can be achieved by intercalation of Au atoms into the interface. This process has been systematically investigated using angle-resolved photoemission spectroscopy, x-ray photoemission, and absorption techniques. It has been demonstra

Popular Abstract in Swedish Artros är en av de vanligaste kroniska sjukdomarna och en av de främsta orsakerna till funktionshinder för människor världen över. Artros angriper ofta knä- och höftlederna och bryter ner det brosk som finns där. För den som drabbats av artros tar förloppet ofta många år, med successivt ökande smärtor och rörelsesvårigheter. Ofta upptäcks dessutom inte sjukdomen förrän Osteoarthritis (OA) is a common chronic disease and one of the major global causes for functional disabilities. The disease is characterized by loss and degradation of cartilage, commonly affecting the knees and hips. Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) is a previously presented method for identification of early OA using magnetic resonance imaging (MRI). By quantifying the T1 p

Five recent techniques from hybrid and optimal control are evaluated on two power electronics benchmark problems. The benchmarks involve a number of practically interesting operating scenarios for fixed-frequency synchronous dc-dc converters. The specifications are defined such that good performance can only be obtained if the switched and nonlinear nature of the problem is accounted for during th

Computing smoothing distributions, the distributions of one or more states conditional on past, present, and future observations is a recurring problem when operating on general hidden Markov models. The aim of this paper is to provide a foundation of particle-based approximation of such distributions and to analyze, in a common unifying framework, different schemes producing such approximations.

In this paper three unit root tests that allow for a break in both the seasonal mean and linear trend of the data are proposed. The tests, which can be seen as smallsample corrected versions of already known asymptotic tests, are shown to perform very well in simulations, and much better than their asymptotic counterparts.

Single top quark production via four-fermion contact interactions associated to flavour-changing neutral currents was searched for in data taken by the DELPHI detector at LEP2. The data were accumulated at centre-of-mass energies ranging from 189 to 209 GeV, with an integrated luminosity of 598.1 pb(-1). No evidence for a signal was found. Limits on the energy scale Lambda, were set for scalar-, v

Problem definition Additive manufacturing is a technology that has received a lot of attention and many are wondering how it will affect them plastic industry in the future. Additive manufacturing is mostly used for prototyping today but there is reason to believe that the technology has potential to overtake other application areas for plastic or used as a complementary method to existing manufac

This thesis work is part of a larger project with final goal to be able to measure the oxygen concentration in the lungs of infants, using non-invasive laser spectroscopy. This thesis is specifically dealing with simulations of light transport through the upper body of infants, as well as constructing a tissue-like model (phantom) that can be used in experiments. The goal is to use these simulatio

Bakgrund: Att vara förälder till barn med funktionsnedsättning innebär ofta ökade stressfaktorer i vardagen med de ökade behov barnet har. Stress, ångest och depression är vanligt förekommande samt bortprioritering av meningsfulla aktiviteter, vilket kan leda till aktivitetsobalans. Syfte: Syftet med studien var att i vetenskapliga studier undersöka interventioner för föräldrar till barn med funkt

Bakgrund: Stroke är en vanlig orsak till att vuxna människor drabbas av fysiska och kognitiva funktionsnedsättningar. Kognition är individens förmåga ta in, tolka och bearbeta information från omgivningen. Att inte klara av att utföra vardagliga aktiviteter så som personlig vård, arbete och fritidsaktiviteter är en vanlig följd av kognitiva funktionsnedsättningar. Syfte: studien har ett tvådelat s

Rehabilitering efter en stroke är viktig för att den drabbade individen ska återfå så stor del av de påverkade kroppsfunktionerna som möjligt. Balansen blir ofta försämrad hos individer som överlevt stroke och behöver stärkas för att inte hindra individen i dennes vardagliga liv. Rehabiliteringsträningen av balansen bör innehålla motivationsfaktorer för att träningen ska ske i tillräckligt stor omThe rehabilitation after a stroke is important for the individual so that the affected body functions recover as much as possible. The balance is often impaired after a stroke and need to be strengthend to not impede the stroke-survivor in the daily life. The rehabilitation training of the balance should include motivation factors for the training to take place in sufficiently large scale. The aim

I Sverige är höghastighetsjärnvägar ett debatterat ämne. Undersökningsarbeten har startat för det första steget i ett höghastighetsnät – Ostlänken mellan Järna och Linköping – som planeras vara trafikerad år 2028. Höghastighetsjärnvägen är avsedd att tillåta hastigheter på 320 km/h. Vid så höga hastigheter blir dimensioneringskraven för brobanans vibrationer strängare. Tidigare studier har visat aIn Sweden, high-speed railways is a subject for public debate. The first stage of a high-speed train network, Ostlänken between Stockholm and Linköping, is under investigation, and is planned to be trafficked in 2028. The high-speed railway is intended to hold traffic with speeds up to 320 km/h. At such speeds, the design requirements of the accelerations of the bridge superstructure become more s