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Objective: To determine if blood neurofilament light chain (NfL) protein can discriminate between Parkinson disease (PD) and atypical parkinsonian disorders (APD) with equally high diagnostic accuracy as CSF NfL, and can therefore improve the diagnostic workup of parkinsonian disorders. Methods: The study included 3 independent prospective cohorts: the Lund (n = 278) and London (n = 117) cohorts,
In 1992 the Core Assessment Program for Intracerebral Transplantations (CAPIT) was published providing the minimal requirements for a common patient evaluation protocol. Despite the intent, the program was thought to be too laborious to carry out in large scale trials, and it also lacked evaluations of cognitive functions and quality of life. Moreover, the CAPIT was designed for neural transplanta
Nanowire array solar cells show intrinsic light trapping and absorption enhancement properties due to the diffraction and optical resonances. Here, we report the effect of varying incidence angle on the performance of GaAs nanowire array solar cells. We provide experimental evidence that nanowire array solar cells are highly efficient at gathering diffuse or tilted incident light, even at very hig
Many subjects have a negative spike in the beginning of a saccade in electro-oculographic signals. The amplitude of the spike depends on the location of the electrodes. The spike distorts the saccades and causes errors in the parameters. The saccade spike can assist in the identification of small saccades. A syntactic technique based on formal languages and parsing is presented which looks for spi
Several recent studies of solar twins in the solar neighbourhood have shown a tight correlation between various elemental abundances and age, in particular [Y/Mg]. If this relation is real and valid for other types of stars as well as elsewhere in the Galaxy, it would provide a very powerful tool to derive ages of stars without the need to resort to determining their masses (evolutionary stage) ve
Structured illumination is an imaging method most commonly employed within the field of microscopy. However, recently the technique has spread into other scientific fields, such as for combustion research, where it has revealed new measurement opportunities. This paper describes how structured illumination can be employed for spray- and combustion research and highlights some of the recent progres
BACKGROUND: The immediate postoperative function of the parathyroid glands after surgery for primary hyperparathyroidism (pHPT) has not been established. We therefore examined the influences of hypercalcemia and hypocalcemia on serum parathyroid hormone (PTH) levels in the immediate postoperative period in patients with pHPT.METHODS: Ethylenediaminetetraacetic acid was infused in patients on the f
Primary hyperparathyroidism (pHPT) is associated with osteopenia. However, the individual variation in recovery in bone mass after surgery is large. Therefore, modes of prediction of the increase in bone mass after parathyroid surgery were investigated. Preoperatively and at one year after surgery bone mineral content (BMC) in the distal radius was measured with single photon absorptiometry techni
We study upscaling of gas high harmonic generation, to make efficient use of the ever increasing laser pulse powers. Loose focusing geometries optimizing phasematching are investigated and compared in HHG efficiency to shorter focusing arrangements.
By comparing the cerebrospinal fluid (CSF) proteome between Alzheimer's disease (AD) patients and controls, it may be possible to identify proteins that play a role in the disease process and thus to study the pathogenesis of AD. Two-dimensional gel electrophoresis (2-DE), SYPRO Ruby staining and mass spectrometry were used for clinical screening of disease-influenced CSF proteins in AD patients c
The concept of double compression, and double expansion engine (DCEE) for improving the efficiency of piston reciprocating engines was introduced in SAE Paper 2015-01-1260. This engine configuration has separate high, and low pressure units thereby effectively reducing friction losses for high effective compression ratios. The presence of an additional expander stage also theoretically allows an e
There are several different preventive measures that can be used to reduce the number of fire fatalities in residential buildings, but information on how effective different measures are for different groups are, however, lacking. As a result, general measures are often implemented on large portions of the total population, which is not as cost-effective as targeting certain measures for certain g
People who suffer from swallowing disorders, commonly referred to as dysphagia, are often restricted to a texture-modified diet. In such a diet, the texture of the fluid is modified mainly by the addition of gum or starch-based thickeners. For optimal modification of the texture, tunable rheological parameters are shear viscosity, yield stress, and elasticity. In this work, the flow properties of
This article focuses on media engagement within the reality television industry. Itdraws on qualitative research of production practices and audience participationin live reality events to explore the multiple meanings of engagement as a series ofrelationships between creative and executive producers, broadcasters, performers,and audiences. A key question concerns how do producers and audiencescoc
Broadband circuit models for electric machines are effective means to understand, predict, and control the phenomenon of conducted Electromagnetic Interference (EMI) from immunity/susceptibility perspective. These models should cover the capacitive and inductive coupling behavior of the component along the frequency range of interest. Circuit models used under generic SPICE simulation softwares ar
