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Feasibility of in vivo N-15 MRS detection of hyperpolarized N-15 labeled choline in rats

The increase of total choline in tumors has become an important biomarker in cancer diagnosis. Choline and choline metabolites can be measured in vivo and in vitro using multinuclear MRS. Recent in vivo C-13 MRS studies using labeled substrates enhanced via dynamic nuclear polarization demonstrated the tremendous potential of hyperpolarization for real-time metabolic studies. The present study dem

Development of NMR spectroscopic methods for dynamic detection of acetylcholine synthesis by choline acetyltransferase in hippocampal tissue.

Choline acetyltransferase (ChAT) is the key-enzyme for acetylcholine (ACh) synthesis and constitutes a reliable marker for the integrity of cholinergic neurons. Cortical ChAT activity is decreased in the brain of patients suffering from Alzheimer's and Parkinson's diseases. The standard method used to measure the activity of ChAT enzyme relies on a very sensitive radiometric assay but can only be

St Gallen molecular subtypes in screening-detected and symptomatic breast cancer in a prospective cohort with long-term follow-up.

Diagnosis by screening mammography is considered an independent positive prognostic factor, although the data are not fully in agreement. The aim of the study was to explore whether the mode of detection (screening-detected versus symptomatic) adds prognostic information to the St Gallen molecular subtypes of primary breast cancer, in terms of 10-year cumulative breast cancer mortality (BCM).

Adeno-associated viral vector serotypes 1 and 5 targeted to the neonatal rat and pig striatum induce widespread transgene expression in the forebrain

Viral vector-mediated gene transfer has emerged as a powerful means to target transgene expression in the central nervous system. Here we characterized the efficacy of serotypes 1 and 5 recombinant adeno-associated virus (rAAV) vectors encoding green fluorescent protein (GFP) after stereotaxic delivery to the neonatal rat and minipig striatum. The efficiency of GFP expression and the phenotype of

Characterization of long-term motor deficits in the 6-OHDA model of Parkinson's disease in the common marmoset.

Research aimed at developing new therapies for Parkinson's disease (PD) critically depend on valid animal models of the disease that allows for repeated testing of motor disabilities over extended time periods. We here present an extensive characterization of a wide range of motor symptoms in the 6-OHDA marmoset model of PD when tested over several months. The severity of motor deficits was quanti

Us-2016-06-22-protokoll-bilagor

Bästa resultat får du om du öppnar den här PDF-portföljen i Acrobat X eller Adobe Reader X eller senare. Hämta Adobe Reader nu! http://www.adobe.com/go/reader_download_se Postadress Box 117, 221 00 Lund Besöksadress Universitetshuset, Paradisgatan 2 Telefon 046-222 00 00 E-post Bo.Ahren@rektor.lu.se Webbadress http://www.lu.se/ Vicerektor Bo Ahrén Rapportering, arbetet med strategi för MAX IV och

https://www.lu.se/sites/www.lu.se/files/us-2016-06-22-protokoll-bilagor.pdf - 2026-06-07

Mess53 prelim 171215

Kursguide - Course Syllabus • • • • Fastställande Kursplanen är preliminär men ännu ej fastställd. Allmänna uppgifter Kursen är en valbar kurs på tredje terminen av LUMES, Masterprogram i miljö- och hållbarhetsvetenskap, 120 högskolepoäng Undervisningsspråk: Engelska Kursens mål För godkänt resultat ska studenten visa: Kunskap och förståelse kritisk kunskap och förståelse för de komplexa sambanden

https://www.lumes.lu.se/sites/lumes.lu.se/files/mess53_prelim_171215.pdf - 2026-06-07

An LO phase shifter with frequency tripling and phase detection in 28 nm FD-SOI CMOS for mm-wave 5G transceivers

This paper presents an LO phase shifter with frequency tripling for 28-GHz 5G transceivers. The phase shifting and frequency tripling are achieved using an injection-locked oscillator and injection-locked frequency tripler, respectively. A phase detector based on third harmonic mixing is also implemented and is used to detect the applied phase shift, supporting automatic calibration of the phase s

Nationella forskarkurser - media-geographies 2017

Namnlös 2016-11-04 Media Geographies (National PhD Course in, Fall semester 2017, 7.5 ECTS) Course organizers: Mekonnen Tesfahuney, Professor, Department of Geography, Media & Communication Karlstad University (mete@kau.se) Richard Ek, Associate Professor, Institute of Service Management, Lunds University (richard.ek@ism.lu.se) André Jansson, Professor, Department of Geography, Media & Communicati

https://www.keg.lu.se/sites/keg.lu.se/files/nationella_forskarkurser_-_media-geographies_2017.pdf - 2026-06-07

Public Programme Immersive Days 3 FINAL

Immersive Days #3: Agents in Play Inter Arts Center 22–24, 26–27 november 2023 PROGRAMME installations at iac, 22–24, 26–27 november, 13:00–17:00 Ali Eslami A Stretch of time. Video installation. Location: Black Room. False Mirror. VR Experience. Maren Dagny Juell Monument for Sim Inventory. AR-work. Location: Research Platform Lick Pick Kick. VR installation. Location: VR/Sound lab. Halla Steinun

https://www.iac.lu.se/sites/iac.lu.se/files/2023-11/Public%20programme%20Immersive%20Days_3_FINAL.pdf - 2026-06-07

Handläggningsordning Horizon Europe 2021-2027

Handläggningsordning för forsknings- och innovationsprojekt inom Europeiska Kommissionens ramprogram Horizon Europe (2021-2027) Sida 1 av 13 Rektor BESLUT Diarienummer STYR 2022/1700 Datum 2022-09-08 Handläggningsordning för forsknings- och innovationsprojekt inom Europeiska Kommissionens ramprogram Horizon Europe (2021– 2027) Denna handläggningsordning (Dnr: STYR 2022/1700) gäller för ansökningar

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2022-11/Handl%C3%A4ggningsordning_Horizon_Europe_2021-2027.pdf - 2026-06-07

Fading in Reflective and Heavily Shadowed Industrial Environments With Large Antenna Arrays

One of the required communication solutions to support novel use cases, e.g. in industrial environments, for 5G systems and beyond is ultra-reliability low-latency communication (URLLC). An enabling technology for URLLC is massive multiple-input multiple-output (MIMO), which with its large antenna arrays can increase reliability due to improved user separation, array gain and the channel hardening

Analysis of Control Systems Under Sensor Timing Misalignments

This paper presents an in-depth analysis of the stability and performance of control systems experiencing sensor timing misalignments, a common challenge in practical applications such as autonomous vehicles and aerospace systems. We model multichannel sensor delays as independent random variables, capturing the variability of real-world systems where different sensors exhibit distinct and non-con

Channel Orthogonalization With Reconfigurable Surfaces : General Models, Theoretical Limits, and Effective Configuration

We envision a future in which multi-antenna technology effectively exploits the spatial domain as a set of non-interfering orthogonal resources, allowing for flexible resource allocation and efficient modulation/demodulation. We may refer to this paradigm as orthogonal space-division multiplexing (OSDM). On the other hand, reconfigurable intelligent surface (RIS) has emerged as a promising technol

Klimatpolitiska rådets rapport 2025

Denna rapport utgör Klimatpolitiska rådets årliga utvärdering av regeringens samlade politik i förhållande till de klimatmål som beslutats av riksdag och regering.Del I är en utvärdering av hur regeringens politik har utvecklats under 2024 och har alltså en tidsmässig avgränsning. För att sätta den utvärderingen i ett sammanhang inleds texten men en kortfattad genomgång av nu gällande klimatmål oc

Storms, ships, and shovels : A trans-Holocene history of the Gullåkra wetland

The Gullåkra wetland is located around 5 km south of the modern city of Lund and around 2.7 km east of the important Iron Age settlement of Uppåkra in Scania, southern Sweden. In the 1840s, a remarkable discovery was made in the wetland: a bronze lur dated to c. 1300 BCE, along with a boat and the bones of a large animal offering. As Bronze Age boats are exceedingly rare, this discovery makes the

Replication package for code review as decision-making

Code review is a well-established and valued practice in the software engineering community contributing to both code quality and interpersonal benefits. However, there are challenges in both tools and processes that give rise to misalignments and frustrations. Recent research seeks to address this by automating code review entirely, but we believe that this risks losing the majority of the interp

ALogSCAN: A Self-Supervised Dual Network for Adaptive and Timely Log Anomaly Detection in Clouds

Logs are prevalent in modern cloud systems and serve as a valuable source of information for system maintenance. Over the years, many supervised, semi-supervised, and unsupervised log analysis methods have been proposed to detect system anomalies. In particular, semi-supervised methods have garnered increasing attention as they balance reduced labeled data requirements and optimal detection perfor