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The origin of the H αline profiles in simulated disc galaxies

Observations of ionized H αgas in high-redshift disc galaxies have ubiquitously found significant line broadening, σH α∼10 -100 km s-1 . To understand whether this broadening reflects gas turbulence within the interstellar medium (ISM) of galactic discs, or arises from out-of-plane emission in mass-loaded outflows, we perform radiation hydrodynamic simulations of isolated Milky Way-mass disc galax

Choice of High-Throughput Proteomics Method Affects Data Integration with Transcriptomics and the Potential Use in Biomarker Discovery

In recent years, several advances have been achieved in breast cancer (BC) classification and treatment. However, overdiagnosis, overtreatment, and recurrent disease are still significant causes of complication and death. Here, we present the development of a protocol aimed at parallel transcriptome and proteome analysis of BC tissue samples using mass spectrometry, via Data Dependent and Independ

Calibration methods for wideband forward RCS measurements

Calibration is an important part in all radar cross section measurements. Two different approaches to the calibration of forward and extinction cross section measurements are therefore evaluated and discussed in this paper. The first method is the commonly used calibration method employing a calibration target with a known cross section while the second calibration method does not require a calibr

Level of sedation in critically ill adult patients : a protocol for a systematic review with meta-analysis and trial sequential analysis

Introduction It is standard of care to provide sedation to critically ill patients to reduce anxiety, discomfort and promote tolerance of mechanical ventilation. Given that sedatives can have differing effects based on a variety of patient and pharmacological characteristics, treatment approaches are largely based on targeting the level of sedation. The benefits of differing levels of sedation mus

Interactions in the 2×2×2 factorial randomised clinical STEPCARE trial and the potential effects on conclusions : a protocol for a simulation study

Background: Randomised clinical trials with a factorial design may assess the effects of multiple interventions in the same population. Factorial trials are carried out under the assumption that the trial interventions have no interactions on outcomes. Here, we present a protocol for a simulation study investigating the consequences of different levels of interactions between the trial interventio

The communication for resilience of urban destinations during the COVID-19 pandemic.

This paper explores how urban Destination Management Organisations (DMOs) in Sweden, have understood their communicative role, developed communicative strategies and tactics during the COVID-19 pandemic. The overall aim of this research is to develop understanding of the role of communication strategies for developing urban destination resilience. This study is conducted in collaboration with the

Follow-up care after out-of-hospital cardiac arrest: A pilot study of survivors and families’ experiences and recommendations

Background and objectives Cognitive and physical difficulties are common in survivors of out-of-hospital cardiac arrest (OHCA); both survivors and close family members are also at risk of developing mood disorders. In the UK, dedicated follow-up pathways for OHCA survivors and their family are lacking. A cohort of survivors and family members were surveyed regarding their experience of post-discha

European Resuscitation Council and European Society of Intensive Care Medicine Guidelines 2021 : Post-resuscitation care

The European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) have collaborated to produce these post-resuscitation care guidelines for adults, which are based on the 2020 International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations. The topics covered include the post-cardiac arrest syndrome, diagnosis of cause of cardiac a

Cesarean Section. Impact on Postpartum Recovery, Subsequent Pregnancy and Delivery.

Women are at increased risk of complications after Cesarean section (CS) postpartum and in subsequent pregnancy and delivery. The overall aim of the thesis was to evaluate complications after CS, outline options for their management and to assess strategies to increase the rate of vaginal deliveries after CS (VBAC).Paper I was a prospective study where women were offered to have an additional appo

Trust dynamics in global software engineering

Trust is one of the key factors that determines success or failure of any software project. However, achieving and maintaining trust in distributed software projects, when team members are geographically, temporally and culturally distant from each other, is a remarkable challenge. This paper explores the dynamics of trust and best practices performed in software organizations to address trust-rel

Pregnancies, ventricular arrhythmias, and substrate progression in women with arrhythmogenic right ventricular cardiomyopathy in the Nordic ARVC Registry

AIMS: Women with arrhythmogenic right ventricular cardiomyopathy (ARVC) are at relatively lower risk of ventricular arrhythmias (VAs) than men, but the physical burden associated with pregnancy on VA risk remains insufficiently studied. We aimed to assess the risk of VA in relation to pregnancies in women with ARVC. METHODS AND RESULTS: We included 199 females with definite ARVC (n = 121) and muta

Rational and evolutionary engineering of Saccharomyces cerevisiae for production of dicarboxylic acids from lignocellulosic biomass and exploring genetic mechanisms of the yeast tolerance to the biomass hydrolysate

Background: Lignosulfonates are significant wood chemicals with a $700 million market, produced by sulfite pulping of wood. During the pulping process, spent sulfite liquor (SSL) is generated, which in addition to lignosulfonates contains hemicellulose-derived sugars—in case of hardwoods primarily the pentose sugar xylose. The pentoses are currently underutilized. If they could be converted into v

Natural killer cell activity and antibody-dependent cellular cytotoxicity in newborn infants

The ability of lymphocytes from the peripheral blood of preterm and term infants and adult women and men to mediate natural killing (NK) and K cell activity (antibody-dependent cellular cytotoxicity) was analysed in 4 hours 51Cr-release assays. K 562 cells were targets for NK activity. K cell activity was assayed on antibody-coated rat thymocytes. Lymphocytes from adult male donors were significan

How Do you Trust? : On Infrastructural Meaning-making and the Need for Self-reflection

The chapter focuses on the notion of critical evaluation of information, which is an important part of media and information literacy (MIL). The concepts frictions of relevance and infrastructural meaningmaking are introduced to shed light on the information infrastructure’s significance for MIL in today’s digital media ecology. Furthermore, the chapter discusses some of the limitations inherent i

Detecting longitudinal changes in activities of daily living (ADL) dependence : Optimizing ADL staircase response choices

Introduction: Using a sum score based on a three-graded response scale for the activities of daily living staircase has previously been found to increase the statistical power compared to dichotomized responses when assessing longitudinal changes in activities of daily living. We aimed to investigate if the statistical power could be further increased by using a four-graded scale. Methods: We used

Effect of high voltage electrical pulses on subcutaneous glioma tumours on rats

The antitumour effect of applied high voltage exponential pulses was investigated on rats with subcutaneously implanted N32 brain tumours. Superficial tumours on the thigh were produced by the injection of 100 000 N32 glioma cells on Fischer-344 rats. Four weeks after inoculation, a solid tumour has grown to a size of about 1 cm located directly under the skin. Short electric high voltage pulses w