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Gaia will observe huge numbers of binaries with a large range of periods. The present contribution tries to present some estimates of the expected number of detections and/or orbit determinations, based on simplified but large-scale simulations. The simulations have to model both a Galaxy with binaries, the instrument and observations, and the reduction programs. As in previous studies, there are
Air samples were collected on glass fibre filters in 22 animal houses and 3 hay storage barns and examined for the presence of bacterial endotoxin with the Limulus (LAL) test and the gas chromatography - tandem mass spectrometry (GC-MSMS) technique, based on detection of 3-hydroxy fatty acids (3-OH-FAs) as chemical markers of the endotoxin lipopolysaccharide. The median concentrations of airborne
Transgenic mice were generated expressing NK1.1, an NK cell-associated receptor, under control of the human CD2 promoter. Unexpectedly, one of the founder lines, Tg66, showed a marked defect in thymic development characterized by disorganized architecture and small size. Mapping of the transgene insertion by fluorescence in situ hybridization revealed integration in chromosome 2, band G. Already f
Summary form only given. Spectra were recorded from a fluorescent light tube under a number of experimental conditions and using different spectroscopic techniques. The motivation of the work was to use spectroscopic techniques for plasma diagnostics purposes. The spectrometers used were a high resolution echelle based instrument and a Fourier transform spectrometer in Lund and a low-resolution in
Popular Abstract in Swedish ?DNA-mikromatriser eller genchips? är idag väletablerade verktyg inom biologisk forskning och klinisk diagnostik. Genmikromatriser kan exempelvis användas för att i mikroskala studera genetiska skillnader mellan sjuka och friska vävnader. Informationen som då erhålls kan ge värdefulla upplysningar om sjukdomens natur och användas vid utveckling av nya läkemedel. GenernAntibody-based microarrays are among the novel class of rapidly evolving proteomic technologies. In recent years, antibody microarrays have emerged as a unique tool for high-throughput protein expression profiling with great promise within biomedicine and a wide range of potential applications, including disease diagnostics and biomarker discovery. In order to evolve the technology from small dedi
Popular Abstract in Swedish Autoimmuna sjukdomar såsom reumatoid artrit (RA) och multipel skleros (MS) uppkommer av en felaktig immunrespons mot kroppens egen vävnad. Orsaken är okänd trots enormt mycket forskning om ämnet. Ett sätt att öka kunskapen vore att identifiera de gener som bidrar till sjukdomarna. För sådana relativt vanliga, komplexa sjukdomar finns det inte en gen som ?styr? sjukdomarAutoimmune diseases are dependent on both genetic and environmental factors in complex interplay. They arise from a faulty immune response against self-antigens, and causes great suffering in affected individuals. Despite large efforts and hundreds of thousands of research articles published, the disease etiologies remain largely unknown. Knowledge of which genes are involved and how they interact
Mankind is already spending beyond the capacity of its planet and trends look very scaring. Big changes in human behaviour are urgent. As pointed out by others there are many ways how Ergonomics/Human Factors/ could contribute to such changes. The aim of this paper is to discuss some lessons learnt from safety performance in aviation and trans¬formed to sustainability, especially the concepts sust
Popular Abstract in Swedish Cancer är ett samlingsnamn på sjukdomar som kännetecknas av okontrollerad celltillväxt. I friskt tillstånd växer kroppens celler kontrollerat. Cancertillståndet startar när någon av dessa celler förändras så att tillväxten ökar. När tillväxten ökar så tilltar också celldelningen. Om ingen åtgärd vidtas kommer cancern till slut att slå ut funktionen hos det organ som denCancer is the collective name for diseases that have one thing in common ? uncontrolled cell growth. The increase in cancer cell proliferation eventually results in tumor formation and, in the worst case, metastatic spread to other organs. Common treatment modalities of cancer include chemotherapy and radiation therapy. However, these methods are associated with severe side effects as well as indu
In this paper, a feature extraction method based on principal component analysis was developed for classification of the vascular access’s condition in hemodialysis patients. The assessment of the method was carried out by discriminating between before and after angioplasty sound recordings as well as before angioplasty and reference recordings. The results showed that when before and after angiop
Professionals who take part in the building process have long been concerned with the same environmental factors, e.g. spatial layout, capacity, and function, as well as user demography. Through the knowledge gained on the ways environmental factors affect users of buildings, the need to understand how to handle these factors has grown, due to their influence on the building process. It will be sh
Popular Abstract in Swedish Antikroppar är viktiga beståndsdelar av det naturliga immunförsvaret som skyddar oss mot smittämnen, såsom bakterier och virus. Utvecklingen av olika genetiska och biokemiska teknologier har dessutom möjliggjort användningen av antikroppar för en mängd ändmål, bl a för diagnostik och behandling av infektionssjukdomar och cancer. I denna avhandling, som bygger på fem vetAntibodies are key players of the immune system in higher vertebrates, which provide a defense against potentially lethal threats from the environment. Besides their importance in the immune defense, antibodies have a great potential as reagents in biological chemistry and diagnostics, and as therapeutic agents against both infectious diseases and cancer. Despite tremendous advances in all fields
Abstract Regnell, Astrid: Att se stjärnor på ljusa dagen. Förvandling och försoning i August Strindbergs En blå bok. Seeing stars in broad daylight. Transformation and Reconciliation in August Strindberg’s Zones of the Spirit. In this thesis a pattern of coherence is explored in August Strindberg’s Zones of the Spirit (En blå bok) – a literary work consisting of a collection of short and quite div
Popular Abstract in Swedish Ärftliga orsaker till ledgångsreumatism och Sjögrens syndrom Ett välfungerande immunförsvar är nödvändigt för att kroppen ska kunna mostå angrepp från virus, bakterier och andra mikroorganismer. Vid en autoimmun sjukdom tror man att immunförsvaret av misstag börjar angripa kroppens egna vävnader, vilket leder till att de förstörs. Hur dessa sjukdomar uppkommer känner mTo understand the pathogenesis of autoimmune diseases we have to consider the problem from different angles. Animal models provide a tool to further understand these complex diseases, as the influence of genetic and environmental factors could be limited. Moreover, modern transgenic techniques have made it possible to study the role of certain genes and gene products in the development of diseases
This paper presents a study of the main advantages of inverted decoupling in 2×2 processes. Two simulation examples and an experimental process are used to show these advantages in comparison with simplified decoupling. The study focuses on the following practical advantages: the apparent process is the same as that obtained if one loop changes to manual; bumpless transfer and anti-windup are achi
The current rapid development within work-environment research has created a considerable demand among industrial hygienists for suitable analytical methods. PIXE (particle-induced X-ray emission analysis), which was introduced in Lund in 1970, has been shown to be a feasible method for use in studying the elemental composition of aerosols. However, in some work environments, fluorine, an element
As emphasized by Jeremy Bentham and the analytical school, logical consistency is a requirement for rational legislation. For understanding consistency between norms, a logical scrutiny of normative conflicts is needed. In our paper, a framework for the fine structure of such conflicts is introduced and explained. “Normative conflict” is defined relative the framework and different types of confli
E. coli continues to be a popular host organism for production of recombinant proteins. To obtain a high volumetric productivity at the cultivation stage, it is important to achieve a high cell density and a high specific productivity per cell. In many fed-batch processes, the substrate feed rate eventually becomes limited by the oxygen transfer capacity of the bioreactor. While biomass can contin
Popular Abstract in Swedish Tryptofan (TRP) är en s.k. essentiell aminosyra d.v.s. den kan inte syntetiseras av kroppen utan måste intas med födan. TRP ingår bl.a. som byggsten i kroppens proteiner men TRP används även som substrat för bildningen av signalsubstansen serotonin (även kallad 5-hydroxytryptamin; 5-HT). Dessutom kan TRP användas för bildningen av de för kroppen livsviktiga molekylerna In the present study, L-tryptophan (TRP)-related disturbances in the brain in experimental hepatic encephalopathy (HE) were investigated. The endogenous NMDA-receptor agonist and L-TRP metabolite quinolinic acid (QUIN) has been suggested to be involved in the pathogenesis of HE. We were, however, unable to detect any increases in QUIN levels in rats subjected to a chronic portacaval shunt (PCS) ei
