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Social‐class segregation in Landskrona

This chapter examines the evolution of social class segregation in the city of Landskrona during the twentieth century. The city’s population was initially spatially mixed with regards to social class but became more segregated with industrialization. The study reveals that the segregation of higher white-collar workers increased drastically from 1940 to 1960, with a concentration of this group in

Active Site Hydrophobicity and the Convergent Evolution of Paraoxonase Activity in Structurally Divergent Enzymes : The Case of Serum Paraoxonase 1

Serum paraoxonase 1 (PON1) is a native lactonase capable of promiscuously hydrolyzing a broad range of substrates, including organophosphates, esters, and carbonates. Structurally, PON1 is a six-bladed β-propeller with a flexible loop (residues 70-81) covering the active site. This loop contains a functionally critical Tyr at position 71. We have performed detailed experimental and computational a

Innovative Methods for Affectivity Profiling : Quantitative Semantics

Background: Affectivity has been suggested as a complex adaptive meta-system composed of positive affect and negative affect, two independent but interrelated markers of well-being, that can be represented as four distinct affective profiles: self-fulfilling (high positive affect/low negative affect), high affective (high positive affect/high negative affect), low affective (low positive affect/lo

Affective Latent Profiles and Personality Dimensions in Spanish Children

Background: During the last years, the affective profiles model has been applied to study individual differences among Spanish children in psychological characteristics, such as optimism and pessimism. This research has replicated past studies from adult and adolescent Swedish populations by identifying four profiles using clustering methods on self-reports of children’s experience of positive (PA

Engineering selectivity of Cutibacterium acnes phages by epigenetic imprinting

Cutibacterium acnes (C. acnes) is a gram-positive bacterium and a member of the human skin microbiome. Despite being the most abundant skin commensal, certain members have been associated with common inflammatory disorders such as acne vulgaris. The availability of the complete genome sequences from various C. acnes clades have enabled the identification of putative methyltransferases, some of the

Multicomponent binders for PcBN performance enhancement in cutting tool applications

This study proposes a novel design of binders for polycrystalline cubic boron nitride (PcBN) cutting tool materials. Well-known binder phases TiC and TiN were combined with transitional metal nitrides ZrN, VN, and HfN. Performance screenings of longitudinal turning Inconel 718 and AISI 316 L highlighted the superior performance of PcBN materials with mixed TiC-ZrN and TiC-VN binders. These two sys

The Case for Studying Non-Muslim Islams

In this article we define a new concept that has not previously been theorized: non-Muslim Islam. We argue that theories and methodologies within Islamic studies produce a hierarchy between Muslim and non-Muslim productions of Islam, prioritizing the first. However, this article highlights that Islam may be produced for other purposes than belief in a deity; Islam may for example be important in p

HIV-2 Neutralization Sensitivity in Relation to Co-Receptor Entry Pathways and Env Motifs

HIV-2, compared to HIV-1, elicits potent and broadly neutralizing antibodies, and uses a broad range of co-receptors. However, both sensitivity to neutralization and breadth of co-receptor use varies between HIV-2 isolates, and the molecular background is still not fully understood. Thus, in the current study, we have deciphered relationships between HIV-2 neutralization sensitivity, co-receptor u

Methods to Transfer Logistics Knowledge to People in Industry

Transfer of logistics knowledge to people can be carried out in a number of ways, in different directions and it can also take different forms from personal contacts in day-to-day work to longterm contracts between the parties. Cooperation is important in order to develop new knowledge. One of the innovations in the area is a "Virtual University" started by a consortium of universities in the Balt

Inside the Ivory Tower- Inventors and Patents at Lund University

The purpose of this thesis is to identify patents invented by researchers at Lund University, to describe the university inventors,and to understand the main factors that influence their patenting activities. The analysis focuses on inventors in relation to their environment. A number of factors influence scientists’ decisions to patent. Internal factors related to individuals such as solving the

Alliansregeringens arbetsmarknadspolitik – en teoretisk analys av vårdnadsbidraget och förvärvsavdraget.

The purpose of this thesis is to analyze how the two Swedish reforms, child-care allowance and earned income tax credit (EITC) will affect the labour supply. The child-care allowance will be introduced in Sweden during 2008. The aim is to increase the freedom of choice for parents regarding their child-care. In order to be eligible to the allowance, the children need to be between the ages of one

South West and Central Asia

This chapter covers prosodic features of languages across Southwestern, Central, and Northern Asia. One representative language from each of the four main language families is passed in review, Turkish (Turkic), Mongolian (Mongolic), Persian (Indo-European), and Georgian (Kartvelian). Owing to a lack of descriptive coverage of the prosody of languages in Central Asia, no comprehensive surveys are

Ascorbic acid attenuates activation and cytokine production in sepsis-like monocytes

Sepsis manifests due to the host's dysregulated immune response to infection. High-dose ascorbic acid (AA) has emerged as a potential treatment of sepsis, yet little is known regarding how AA influences the immune system in sepsis, such as monocytes. The objective of this study is to investigate the effects of high-dose AA on monocyte polarization and cytokine production in vitro. Monocytes isolat

Gene Expression Regulation in Airway Pathogens : Importance for Otitis Media

Otitis media (OM) is an inflammatory disorder in the middle ear. It is mainly caused by viruses or bacteria associated with the airways. Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis are the three main pathogens in infection-related OM, especially in younger children. In this review, we will focus upon the multifaceted gene regulation mechanisms that are well-orchestra

Shunt-type plexiform lesions identified in the Sugen5416/Hypoxia rat model of pulmonary arterial hypertension using SPµCT

We recently described four distinct types of plexiform lesions in human idiopathic and familial pulmonary arterial hypertension (PAH) [1], visualising the three-dimensional lesion structure using synchrotron-based phase-contrast micro-CT (SPµCT). Two types, 1 and 2, are shunt-type lesions that connect pulmonary arteries to the bronchial circulation: type 1 to the vasa vasorum, and type 2 to peribr

Column separation of monocytes by adherence to gelatin beads

This investigation was performed to study whether the efficient binding of collagen to monocytes in the presence of fibronectin and heparin may be used for separation of monocytes from human peripheral blood. It was shown that monocytes adhere selectively to gelatin bead columns in the presence of fresh plasma and heparin. Mononuclear blood cells are rapidly depleted of monocytes by passage throug

Host Defense Peptides LL-37 and Lactoferrin Trigger ET Release from Blood-Derived Circulating Monocytes

Neutrophils are commonly regarded as the first line of immune response during infection or in tissue injury-induced inflammation. The rapid influx of these cells results in the release of host defense proteins (HDPs) or formation of neutrophil extracellular traps (NETs). As a second wave during inflammation or infection, circulating monocytes arrive at the site. Earlier studies showed that HDPs LL

Nanosensors for animal infectious disease detection

Infectious diseases in farm animals triggered by pathogenic microorganisms affect the health and well-being of livestock and human populations. Pathogen detection is an important step for the successful diagnosis, treatment and control of infectious diseases in animals. Pathogens that persist in the poultry and livestock industries can be responsible for more than 70% of emerging infections. Thus,

Focusing on the heroines in the novels Ivanhoe and The White Company: Peripheral but important

It is now well established that there is a reciprocal relationship between the content of literature and societal norms. Within feminist criticism, this has been highlighted as problematic, as women are often not portrayed fairly. In this essay, I will examine the relationship between literature and society by comparing the 19th-century Medieval novels Ivanhoe (1819) by Sir Walter Scott and The Wh

Distinct immune microenvironments in ovarian cancer subtypes indicate potential for immunotherapies

BackgroundTo enable immunotherapy for ovarian cancers, precision targets for immune priming as well as patient stratification approaches are required. The tumor microenvironment in particularly the rare subtypes of low-grade serous, mucinous, clear cell and endometrioid ovarian cancer, remains poorly characterized, and these tumors have been largely ignored in the immuno-oncology setting.MethodsWe