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Generating Dendritic Cells by Direct Cell Reprogramming. Merging cellular reprogramming with immunology towards the development of novel cancer immunotherapies.

Cell fate reprogramming towards pluripotency or alternative somatic cell-types has highlighted the plasticity of adult somatic cells, providing new technologies to generate desired cell types for tissue repair or for disease modeling. There is momentum to bring these concepts to immunology by specifying unique immune cellular identities that set in motion immune responses. Dendritic cells (DCs) ar

High-frequency news sentiment and its application to forex market prediction

Financial news has been identified as an important alternative information source for modeling market dynamics in recent years. While most of the attention goes to stock markets, the foreign exchange (Forex) market, in contrast, is much less studied. Most of the existing text mining research for the Forex market combine news sentiment with other text features, making the contribution of each facto

När objektivitet blir subjektiv

Sammanfattning Titel: När objektivitet blir subjektivt: En empirisk studie om hur marknadsinformation påverkar upplevelsen av produkter Seminariedatum: 2026-01-15 Ämne/kurs: FEKH29, Examensarbete i marknadsföring på kandidatnivå, 15 högskolepoäng Författare: Anton Fagerström, Kayvan Souzani, Oliver Svensson Applewhaite Handledare: Jon Bertilsson Fem nyckelord: Upplevt värde, Betalningsvilja, InAbstract Title: When Objectivity Becomes Subjective: An Empirical Study of How Market Information Influences Product Perception Seminar date: 2026-01-15 Course: FEKH29, Degree project in Marketing at Undergraduate level, 15 University Credits Points (UCP) or ECTS Authors: Anton Fagerström, Kayvan Souzani, Oliver Svensson Applewhaite Advisor: Jon Bertilsson Key Words: Perceived Value, Willingness t

Mandible Movements in Japanese : A Comparative Study with Mandarin Speakers

This study analyzed Japanese mandible movements using a recently developed technique, the MARRYS helmet [Gudmundsson et al., Interspeech (2024)]. Data were collected from 9 first language and 10 second language (Mandarin Chinese) speakers of Japanese. The speech materials included three sentences composed entirely of /a/ vowels, one neutral sentence and three focus sentences with emphasis on diffe

New-Onset Atrial Fibrillation During ST-Segment–Elevation Myocardial Infarction : Risk of Recurrence and Its Clinical Impact During 10Years of Follow-Up

BACKGROUND: Atrial fibrillation (AF) often complicates ST-segment–elevation myocardial infarction (STEMI), but data on AF recurrence after first-ever AF during STEMI are scarce. We aimed at assessing the risk of AF recurrence after first-ever transient AF during admission for STEMI. METHODS: We performed a single-center, register-based cohort study. Patients with STEMI discharged alive after prima

Local impact of roughness topography on heat transfer in turbulent flow over rough surfaces

Additive manufacturing (AM), particularly Laser Powder Bed Fusion, produces surfaces with unique, randomly distributed spherical roughness that significantly influences heat transfer and pressure loss. This study models AM roughness using a statistical distribution of spheres and performs high-fidelity simulations at a bulk Reynolds number of 12,000 to evaluate heat transfer on a rough pipe. Stati

Long-term migration of monoblock vs modular design in uncemented total knee arthroplasty : a secondary report of a randomized trial using radiostereometric analysis

Background and purpose — Backside wear of the polyethylene insert in total knee arthroplasty (TKA) has been described to produce clinically significant levels of polyethylene debris, which can lead to aseptic loosening and osteolysis. Monoblock design eliminates backside wear of the polyethylene and therefore could improve long-term fixation. This randomized clinical trial (RCT) using radiostereom

Multilateration as an Eigenvalue Problem

Multilateration, positioning a receiver using pseudodistances to known senders, is a problem with 5G and GNSS positioning applications. In contrast, trilateration uses direct distances and was reformulated as an eigenvalue problem in a recent work, resulting in a very competitive positioning method. This paper extends that reformulation to a more general class of problems subsuming multilateration

CD46 Activation Regulates miR-150-Mediated Control of GLUT1 Expression and Cytokine Secretion in Human CD4+ T Cells.

CD46 is a cell surface complement inhibitor widely expressed in human tissues, in contrast to mice, where expression is limited to the testes. In humans, it has been identified as an important T cell costimulatory receptor, and patients deficient in CD46 or its endogenous ligands are unable to mount effective Th1 T cell responses. Stimulation of human CD4(+) T cells with CD3 and CD46 also leads to

Risk of Birth Abnormalities in the Offspring of Men With a History of Cancer: A Cohort Study Using Danish and Swedish National Registries.

Background The potential mutagenic effects of cancer therapies and the growing number of young male cancer survivors have given rise to concern about the health of their offspring. Methods We identified all singleton children born alive in Denmark between 1994 and 2004 and in Sweden between 1994 and 2005 (n = 1 777 765). Of the 8670 children with a paternal history of cancer, 8162 were conceived n

Adiposity in children born small for gestational age is associated with β-cell function, genetic variants for insulin resistance and response to growth hormone treatment.

Genetic susceptibility to insulin resistance is associated with lower adiposity in adults. Insulin resistance, and therefore adiposity, may alter sensitivity to Growth Hormone (GH). We aimed to determine the relationship between adiposity, genetic susceptibility to insulin resistance or insulin secretion, and response to GH treatment in short children born small for gestational age (SGA).

Truncated and Full-Length Thioredoxin-1 Have Opposing Activating and Inhibitory Properties for Human Complement with Relevance to Endothelial Surfaces.

Thioredoxin (Trx)-1 is a small, ubiquitously expressed redox-active protein with known important cytosolic functions. However, Trx1 is also upregulated in response to various stress stimuli, is found both at the cell surface and secreted into plasma, and has known anti-inflammatory and antiapoptotic properties. Previous animal studies have demonstrated that exogenous Trx1 delivery can have therape

Effects of various reactions on the gas flow and heat transfer in an anode duct of ITSOFCS

Recently, there has been considerable interest in the internal reforming reactions of solid oxide fuel cells (SOFCs) using methane or natural gas via. The internal reforming and electrochemical reactions appear in the porous anode layer, and may lead to inhomogeneous temperature and gas species distributions according to the reaction kinetics. A three-dimensional calculation method has been furthe

Solar control of meteor radar rates

Meteor radar observations carried out in August-September 1953-84 at theOnsala Space Observatory in Sweden show long-term, as well as short termvariations in meteor radar rates. These rate variations are associatedwith position in the solar cycle, and with variations in the solar windsector structure. An inverse correlation is found between meteor radarrates and the solar cycle. The magnitude of t

Force and Acceleration Sensor Fusion for Compliant Robot Motion Control

In this work, we present implementation and experiment of the theory of dynamic force sensing for robotic manipulators, which uses a sensor fusion technique in order to extract the contact force exerted by the end-effector of the manipulator from those measured by a wrist force sensor, which are corrupted by the inertial forces on the end-effector. We propose a new control strategy based on multis

Carsim: A System to Convert Written Accident Reports into Animated 3D Scenes

This paper describes a system to create animated 3D scenes of car accidents from reports written in Swedish. The system has been developed using news reports of varying size and complexity. The text-to-scene conversion process consists of two stages. An information extraction module creates a tabular description of the accident and a visual simulator generates and animates the scene. We first des

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Our investigation of two EPR and waste management programs in California, U.S. revealed two common features: involvement of the state government is small, and the establishment of concrete recycling/waste management systems is to a large extent left in the hands of entities who have direct responsibility for their implementation. Based on the degree of government involvement, we categorized recycl