Sökresultat

Counterintuitive Electrostatics upon Metal Ion Coordination to a Receptor with Two Homotopic Binding Sites

The consecutive binding of two potassium ions to a bis(18-crown-6) analogue of Tröger’s base (BCETB) in water was studied by isothermal titration calorimetry using four different salts, KCl, KI, KSCN, and K2SO4. A counterintuitive result was observed: the enthalpy change associated with the binding of the second ion is more negative than that of the first (ΔH°bind,2 < ΔH°bind,1). This remarkable f

De-bordering and re-bordering practices at the intersection of gender and migration. A multi-site exploration of specialized services for migrant women experiencing violence in Italy and Sweden

This study builds on analyses of everyday professional practices to explore de-bordering and re-bordering processes in the field of gender-based violence (GBV). The concepts of de-bordering and re-bordering practices express the tensions arising from the conflictual roles taken on by civil society actors (CSAs) in their double vest of service delivery for the state and advocate for migrant women w

Do women have to be extraordinary to get exhibited in Swedish museums? : Cultural Heritage Sites, Museum Exhibitions and the Commercialization of Women from the Past

Pulseq-CEST : Towards multi-site multi-vendor compatibility and reproducibility of CEST experiments using an open-source sequence standard

PURPOSE: As the field of CEST grows, various novel preparation periods using different parameters are being introduced. At the same time, large, multisite clinical studies require clearly defined protocols, especially across different vendors. Here, we propose a CEST definition standard using the open Pulseq format for a shareable, simple, and exact definition of CEST protocols.METHODS: We present

The effect of surgical-site infections on patient-reported cosmetic outcomes of scars in dermatological surgery

Green roofs, stormwater and sustainability : Augustenborg as a research site

From a rural idyll to an industrial site: an analysis of hydraulic fracturing energy sprawl in Central Appalachia

This paper analyzes land-system dynamics changes due to energy infrastructure development and explores the environmental and social ramifications of hydraulic fracturing, through a case study in Central Appalachia. Grounded in photographic data, satellite images, and ethnographic material, this study demonstrates landscape and embodied experiences of change over time. Data show major shifts in ter

Lorcaserin bidirectionally regulates dopaminergic function site-dependently and disrupts dopamine brain area correlations in rats

Lorcaserin, which is a selective agonist of serotonin2C receptors (5-HT2CRs), is a new FDA-approved anti-obesity drug that has also shown therapeutic promise in other brain disorders, such as addiction and epilepsy. The modulation of dopaminergic function might be critical in the therapeutic effect of lorcaserin, but its exact effect is unknown. Here, we studied the effect of the peripheral admini

Protein Folding Studied by Site Directed Mutagenesis

The N-terminal RNA binding domain of U1A has been shown to fold in a two-state process without accumulating any intermediates. U1A has a symmetrically curved chevron plot which seems to result mainly from changes of the transition state. At low concentrations of denaturant the transition state occurs early in the folding reaction, whereas at high denaturant concentration it moves close to the nati

From blank spot to focal point. An eastern Swedish site from a south Scandinavian perspective

Particle Number Size Distributions at an Urban Site in southern Sweden: Estimates of the Contribution of Urban Particle Sources

Evolving the binding site of aHCMV neutralizing MoAB through fine specificity studies with AD-1 mutants.

Diurnal and weekly variation of particle number size distributions at an urban site in Malmö and a comparison to rural background

Perfomance Modelling and Control of Distributed E-commerce Sites

Effective outer scale estimation for Euro50 site

Chemical and pharmacological characterization of new ligands for the benzodiazepine-binding site in the GABAA receptor complex.

Ritual building and ritual space. Aspects of investigations at the Iron Age central site Uppåkra, Scania, Sweden

Siting conflicts in renewable energy projects in Sweden: a biogas case study

IS IT – a Site Description

Uppåkra, an Iron Age site with a long duration: internal and external perspectives