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Cancer follow-up supported by patient-reported outcomes in patients undergoing intended curative complex surgery for advanced cancer

Background and aim: Patient activation (PA) and Patient Involvement (PI) are considered elements in good survivorship. We aimed to evaluate the effect of a follow-up supported by electronic patient-reported outcomes (ePRO) on PA and PI. Method: From February 2017 to January 2019, we conducted an explorative interventional study. We included 187 patients followed after intended curative complex sur

Time-range FDA beampattern characteristics

Current literature show that frequency diverse arrays (FDAs) are able of producing range–angle-dependent and time-variant transmit beampatterns, but the resulting time and range dependencies and their characteristics are still not well understood. This paper examines the FDA transmission model with an emphasis on analyzing the beam auto-scanning characteristics and the equivalence with the MIMO be

High-Throughput Hyperparameter-Free Sparse Source Location for Massive TDM-MIMO Radar : Algorithm and FPGA Implementation

The sparse iterative covariance-based estimation (SPICE) algorithm is promising for hyperparameter-free sparse source location for time-division-multiplexing multiple-input-multiple-output (TDM-MIMO) radar systems, with well-documented merits in resolution enhancement and sidelobe suppression. Regrettably, the method typically requires a large number of iterations to converge, each requiring high-

A Comprehensive Robustness Analysis of Storj DCS Under Coordinated DDoS Attack

Decentralized Cloud Storage (DCS) is considered to be the future for sustainable data storage within Web 3.0, in which we will move from a single cloud service provider to creating an ecosystem where anybody could be a cloud storage provider. Currently, the cloud storage market is highly dominated by centralized players like Amazon S3, Google Cloud, Box, etc. Decentralized projects like Storj, Fil

Optimal microphone selection for aero-engine acoustic measurement

Acoustic testing is crucial in the aero-engine design process, providing valuable information about the sound field in terms of acoustic modes. The conventional use of a uniform sampling array limits the achievable resolution for a given number of sensors, necessitating the use of a large number of sensors to achieve high-resolution estimates. This limitation may be overcome using a non-uniform se

CLOSE-RANGE DIRECTION OF ARRIVAL ESTIMATION IN THE PRESENCE OF CLOCK JITTER

Many forms of small-size radars suffer from minor clock oscillations due to crystalline impurities in their internal clocks, causing time-varying clock offsets between the transmitter and the receivers. This offset causes a bias and an increased variance in the positioning of close-range targets, limiting the achievable accuracy well beyond the expected estimation limitations. This performance is

ADAPTIVE GRID 2-D DIRECTION OF ARRIVAL ESTIMATION METHOD USING AN INTEGRATED DICTIONARY

This paper develops an adaptive grid two-dimensional (2-D) direction-of-arrival (DOA) estimation technique employing an integrated dictionary framework. In contrast to using a traditional grid over distinct angles, combined angle information atoms are adopted to construct the dictionary, using a SPICE-based noise power estimate to select the active regions. To compensate for off-grid bias effects,

BERT based natural language processing for triage of adverse drug reaction reports shows close to human-level performance

Post-marketing reports of suspected adverse drug reactions are important for establishing the safety profile of a medicinal product. However, a high influx of reports poses a challenge for regulatory authorities as a delay in identification of previously unknown adverse drug reactions can potentially be harmful to patients. In this study, we use natural language processing (NLP) to predict whether

Phosphodiesterase 5 and its inhibitors with ischemic heart disease : a Mendelian randomization analysis and a real-world study

BACKGROUND: Accumulating studies reported that several phosphodiesterases (PDEs) inhibitors might have cardiovascular benefits.OBJECTIVES: This study aimed to explore the relationship between genetically-predicted PDEs and ischemia heart disease via drug target Mendelian randomization (MR) approach, and then examine the effect of inhibitors of identified target on the outcomes by using real-world

Diet and lifestyle factors and risk of atherosclerotic cardiovascular disease—a prospective cohort study

Atherosclerotic cardiovascular disease (ACVD) is the leading cause of death worldwide. This study aimed to investigate the association between diet and lifestyle factors, beyond traditional risk factors, and the risk of incident ACVD. The Malmö Diet and Cancer study included 30,446 middle-aged individuals. Baseline examinations including a dietary assessment, questionnaire and interviews, were per

Efficiency Optimization by In-Cycle Closed-Loop Combustion Control

This paper is a comprehensive review of in-cycle closed-loop combustion controllers to achieve higher indicated efficiencies. Closed-loop combustion control reduces the effect of external disturbances and system uncertainties, which permit tighter safety margins and robust operation with a reduced calibration effort. The paper combines different components of previous investigations by the authors

Late mortality among survivors of childhood acute lymphoblastic leukemia diagnosed during 1971–2008 in Denmark, Finland, and Sweden : A population-based cohort study

Objective: Investigate all-cause and cause-specific late mortality after childhood acute lymphoblastic leukemia (ALL) in a population-based Nordic cohort. Methods: From the cancer registries of Denmark, Finland, and Sweden, we identified 3765 five-year survivors of ALL, diagnosed before age 20 during 1971–2008. For each survivor, up to five matched comparison subjects were randomly selected from t

Subgroups of patients with young-onset type 2 diabetes in India reveal insulin deficiency as a major driver

AIM/HYPOTHESIS: Five subgroups were described in European diabetes patients using a data driven machine learning approach on commonly measured variables. We aimed to test the applicability of this phenotyping in Indian individuals with young-onset type 2 diabetes.METHODS: We applied the European-derived centroids to Indian individuals with type 2 diabetes diagnosed before 45 years of age from the

Perception of slipperiness, thermal comfort and wearability of footwear used on icy surfaces

The objectives of this study are to assess the perception of slipperiness, thermal comfort, and wearability of footwear used on icy surfaces, and the anti-slip effect of materials spread on ice using outdoor walking trials. Twenty-five subjects wore four types of footwear walking on five different icy surfaces. Five-point rating scale was used recording wearer's perception. The results showed that

Climate Change and Residential Energy Use in Europe : Assessing Future Energy Demands and Renewable Generation Potentials

In recent years, climate change and the corresponding expected extreme weather conditions have been widelyrecognized as potential problems. The construction industry is taking various actions to achieve sustainabledevelopment, implement energy conservation strategies, and provide climate change mitigation. In addition tomitigation, it is crucial to adapt to climate change, and to investigate the p

Sex differences in off-target binding using tau positron emission tomography

Purpose: Off-target binding in the skull and meninges is observed in some subjects undergoing tau positron emission tomography (PET) and could potentially differ between men and women. In this study we elucidate sex differences in tau off-target binding using three different tau PET tracers. Methods: 541 cognitively unimpaired amyloid-β negative participants underwent tau PET using [18F]flortaucip

Epidemiology of firearm injuries in Sweden

Background: Gun violence is a global health problem. Population-based research on firearm-related injuries has been relatively limited considering the burden of disease. The aim of this study was to analyze nationwide epidemiological trends of firearm injuries. Methods: This is a retrospective nationwide epidemiological study including all patients with firearm injuries from the Swedish Trauma Reg

Effect of second-trimester sonographic cervical length on the risk of spontaneous preterm delivery in different risk groups : A prospective observational multicenter study

Introduction: The aim of the study is to compare the effect of cervical length measured with transvaginal ultrasound in the second trimester on the risk of spontaneous preterm delivery (PTD) between different risk groups of asymptomatic women with a singleton pregnancy. Material and methods: This is a pre-planned exploratory analysis of the CERVIX study, a prospective blinded multicenter diagnosti