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BackgroundSevere perineal trauma (SPT) affecting the anal sphincter muscle complex is a serious complication following childbirth, associated with short-term and long-term maternal morbidity. Effective preventive strategies are still scarce. The aim of the Oneplus trial was to test the hypothesis that the presence of a second midwife during the second stage of labour, with the purpose of preventin

While the political aspects of the interwar dystopias have received much attention, less focus has been given to the specific correlation to the economic thinking and developments of the period, in particular the prominence of economic planning. This article suggests that such a connection is significant by examining a key Swedish novel from the period, Kallocain, in relation to the early economic

The knowledge of the material budget with a high precision is fundamental for measurements of direct photon production using the photon conversion method due to its direct impact on the total systematic uncertainty. Moreover, it influences many aspects of the charged-particle reconstruction performance. In this article, two procedures to determine data-driven corrections to the material-budget des

Executive functions (EF) denote the host of top-down mental processes that mediate self-regulation to achieve a goal. Among other things, EF support cognitive flexibility by allowing inhibition of automatic responses in favour of obtaining future goals. Corvids, the bird group that is comprised of ravens, crows and jays, are distinguished by their cognitive flexibility. This thesis investigates tw

Singing in groups and choirs is one of the main and generally most widespread musical activities: in schools at all levels among children and adolescents as well as in leisure time activities from "non-singer choirs" to more advanced and professional choirs. Previous studies indicate the need to identify vocal collaboration between choral singers. This article investigates how individuals in a cho

This introductory chapter gives an overview of the intricate relation between Heidegger and theology. Firstly, it discusses Heidegger’s indebtedness to theology by revisiting the debate that was initiated by the publication of his early Freiburg lectures in the 1990s. Second, it sketches in broad strokes the reception history of Heidegger’s works within twentieth century theology. In the third and

IMPORTANCE: The value of microRNAs (miRNAs) as biomarkers has been investigated in various clinical contexts. Initial small-scale studies suggested that miRNAs might be useful indicators of outcome after cardiac arrest. OBJECTIVE: To address the prognostic value of circulating miRNAs in a large cohort of comatose patients with out-of-hospital cardiac arrest. DESIGN, SETTING, AND PARTICIPANTS: This

This paper describes the challenges concerning measuring quality within the field of emergency response, and discusses specific examples within fire response. Using quality as a standard of measurement to evaluate response efforts of trained personnel at emergency events can lead to increased effectiveness in the response phase of an emergency event; thereby saving additional lives, property, and

Increased tissue stiffness is a classic characteristic of solid tumors. One of the major contributing factors is increased density of collagen fibers in the extracellular matrix (ECM). Here, we investigate how cancer cells biomechanically interact with and respond to the stiffness of the ECM. Probing the adaptability of cancer cells to altered ECM stiffness using optical tweezers based micro-rheol

There is an extensive research that explores the reproduction of transnational communities and relations, with a particular focus on locality, identity and culture. However, the existing literature on transnational migration is largely based on the case studies of immigrant communities living in the United States and Western Europe, while not much has been said about the transnational practices of

It is widely believed that DC, but not macrophages, prime naïve T cells in vivo. Here, we investigated the ability of CD68-expressing cells (commonly defined as macrophages) in priming autoreactive T cells and initiating collagen-induced arthritis (CIA) in the mouse. For this purpose, a transgenic mouse was developed (MBQ mouse) where macrophages exclusively expressed the MHC class II H2-A(q) (A(q

The existence of T cells restricted for the MHC I-like molecule CD1 is well established, but the function of these cells is still obscure; one implication is that CD1-dependent T cells regulate autoimmunity. In this study, we investigate their role in experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis, using CD1-deficient mice on a C57BL/6 background. We show t