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Decrease in REM latency and changes in sleep quality parallel serotonergic damage and recovery after MDMA: a longitudinal study over 180 days

The recreational drug ecstasy [3,4-methylenedioxymethamphetamine (MDMA)], has been found to selectively damage brain serotonin neurons in experimental animals, and probably in human MDMA users, but detailed morphometric analyses and parallel functional measures during damage and recovery are missing. Since there is evidence that serotonin regulates sleep, we have compared serotonergic markers para

Chemical composition and morphology of individual aerosol particles from a CARIBIC flight at 10 km altitude between 50 degrees N and 30 degrees S

Analysis of individual particles by analytical electron microscopy as well as quantitative analysis using particle-induced X-ray emission (PIXE) and particle elastic scattering analysis (PESA) were carried out on samples collected from a flight at 10 km altitude between 50 degrees N and 30 degrees S as part of the Civil Aircraft for Regular Investigation of the atmosphere Based on an Instrument Co

Early patient contact in primary care: a new challenge

Background The Medical School of Lund University, Sweden, has introduced an early patient contact course, including training in communication and examination skills. The course runs parallel with theoretical subjects during the students' first two-and-a-half years. General practitioner (GP) participation is gradually increasing, and in the last half-year of the course GPs in all health centres in

Low Recurrence Rate After Laparoscopic (TEP) and Open (Lichtenstein) Inguinal Hernia Repair A Randomized, Multicenter Trial With 5-Year Follow-Up

Objectives: To compare a laparoscopic (totally extraperitoneal patch (TEP)) and an open technique (Lichtenstein) for inguinal hernia repair regarding recurrence rate and possible risk factors for recurrence. Summary Background Data: Laparoscopic hernia repair has been introduced as an alternative to open repair. Short-term follow-tip suggests benefits for those patients operated with a laparoscopi

Influence of urban morphology and sea breeze on hot humid microclimate: the case of Colombo, Sri Lanka

Urbanisation leads to increased thermal stress in hot-humid climates due to increased surface and air temperatures and reduced wind speed. We examined the influence of urban morphology and sea breeze on the microclimate of Colombo, Sri Lanka. Air and surface temperatures, humidity and wind speed were measured at 1 rural and 5 urban sites during the warmest season. The urban sites differed in their

Cerebral energy metabolism during transient hyperglycemia in patients with severe brain trauma

Objective: To study whether transient hyperglycemia adversely affects cerebral energy metabolism in patients with severe traumatic brain lesions. Design and setting: Prospective, nonrandomized study in the neurosurgical intensive care unit of a university hospital. Patients: 108 patients treated for severe traumatic brain lesions. Interventions: All patients were treated according to neurosurgical

A decade of progress in understanding the structural basis of protein synthesis

The key reaction of protein synthesis, peptidyl transfer, is catalysed in all living organisms by the ribosome - an advanced and highly efficient molecular machine. During the last decade extensive X-ray crystallographic and NMR studies of the three-dimensional structure of ribosomal proteins, ribosomal RNA components and their complexes with ribosomal proteins, and of several translation factors

Conditions related to solubility of rare and minor elements in forest soils

Soil solutions expelled by high-speed centrifugation (13900 g) of intact soil sample cores at field moisture froth 30 forest topsoils (A horizons of mainly Dystric and Eutric Cambisols, according to the FAO-Unesco system) low in day, were subjected to, analysis of 60 elements, using ICP-MS and ICP-AES. Concentrations measured were related to soil, and soil solution, properties, assumed to be impor

Thomas Pugh

Senior lecturer Contact details Email: thomas [dot] pugh [at] mgeo [dot] lu [dot] se Mobile: +46 46 222 86 97Organisation Department of Earth and Environmental Sciences (MGeo) Room number: 363 Service point: 16 WebpageThomas Pughs profile in Lund University research portalOther affiliations Senior lecturer Dept of Physical Geography and Ecosystem Science Member of Strategic Research Area BECC: Bio

https://www.nateko.lu.se/thomas-pugh - 2026-06-06

Infection events in the fungus-nematode system

Infection of vermiform nematodes by nematophagous fungi generally follows the same route whether the nematode is captured in adhesive traps of predatory fungi or mediated by conidia of endoparasites. A successful infection always results in complete digestion of the nematode corpus. The total time for the infection process varies between fungal species and also between species of nematodes being p

Central nervous processing of sex pheromones in two strains of the European corn borer Ostrinia nubilalis (Lepidoptera : Pyralidae)

Antennal lobe neurones were investigated in the pyralid moth Ostrinia nubilalis using intracellular recording and staining techniques. Response characteristics of antennal lobe neurones from males in the so-called E and Z strains, in F1 hybrids and in parental backcrosses were studied. The antennal lobe of a male O. nubilalis comprises approximately 30 ordinary glomeruli and three enlarged glomeru

A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity : results from a large European cohort

Abdominal and general adiposity are independently associated with mortality, but there is no consensus on how best to assess abdominal adiposity. We compared the ability of alternative waist indices to complement body mass index (BMI) when assessing all-cause mortality. We used data from 352,985 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC) and Cox proport

A conceptual framework for an integrated lignin biorefinery-petroleum refinery

Co-feeding of renewable feedstocks in general, and lignin streams in particular, in petroleum refineries is an attractive means of increasing the proportion of renewable fuel. Four separate units in an integrated refinery can be envisioned using lignin as a feedstock: the hydrotreater, the fluidised catalytic cracker, the hydrocracker and the slurry hydrotreater. A conceptual process design study,

Survival and prognostic factors after transplantation, resection and ablation in a national cohort of early hepatocellular carcinoma

Background: In patients with early hepatocellular cancer (HCC) and preserved liver function, the choice between transplantation, resection and ablation and which factors to consider is not obvious and guidelines differ. In this national cohort study, we aimed to compare posttreatment survival in patients fulfilling predefined criteria, and to analyse preoperative risk factors that could influence

PLM used as a backbone for concurrent engineering in supply chain

Supply chain management and early involvement of suppliers into product development process is one of the key elements of concurrent engineering. Internet based Product Lifecycle Management (PLM) system can improve communication between customers and suppliers. In the case study is presented a communication model and configuration of the PLM system that supports a second tier system supplier in au

Aortic stiffness and left ventricular diastolic function in children with well-functioning bicuspid aortic valves

AIMS: Aortic stiffness and diastolic function are abnormal in adults with bicuspid aortic valves (BAVs). The goal of this study was to determine the relationship between aortic stiffness and left ventricular (LV) diastolic impairment in children with well-functioning BAV and no associated congenital heart disease.METHODS AND RESULTS: This is a retrospective review of echocardiograms in children wi

Cryptorchidism in Sweden : A Nationwide Study of Prevalence, Operative Management, and Complications

Objectives: To review the cumulative prevalence, operative management, and complications of treatment for cryptorchidism in Sweden. Study design: A nationwide observational study from longitudinal register data of all Swedish-born boys 0-18 years of age, diagnosed with cryptorchidism from 2001 to 2014. Primary outcomes were occurrence and age at primary surgery. Secondary outcomes included type of