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Transcriptional regulators of GntR family in Streptomyces coelicolor A3(2): analysis in silico and in vivo of YtrA subfamily.

Transcriptional factors of the GntR family regulate numerous physiological and morphological processes in response to the nutrient state of bacterial cells. The number of GntR transcriptional factors in genomes of soil-dwelling actinomycetes is one of the highest among bacteria, reflecting both the large size of their chromosomes and the complex ecological niche that they occupy. However, very lit

Visible-to-ultraviolet upconversion in Pr3+: Y2SiO5 crystals

The visible-to-ultraviolet upconversion in Pr3+:Y2SiO5 crystals have been investigated at room temperature for three different Pr3+ ion concentrations. The upconverted luminescence bands at the UV region from 270 to 350 nm were obtained with visible laser excitation. The upconversion mechanism was studied by observing the absorption and excitation spectra, the dependence of upconverted luminescenc

Reduction in snow depth negatively affects decomposers but impact on decomposition rates is substrate dependent

Decomposition of organic matter in high latitude biomes makes a significant contribution to global fluxes of nutrients and carbon and is expected to accelerate due to climate change. The majority of studies have focused on decomposition during the growing season, but winter climate is expected to change dramatically. Furthermore, knowledge of the drivers of organic matter decomposition, such as li

New aspects of HbA1c as a risk factor for cardiovascular diseases in type 2 diabetes: an observational study from the Swedish National Diabetes Register (NDR)

Eeg-Olofsson K, Cederholm J, Nilsson PM, Zethelius B, Svensson A-M, Gudbjornsdottir S, Eliasson B (Institute of Medicine, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg; Department of Public Health and Caring Sciences/Family Medicine and Clinical Epidemiology, Uppsala University, Uppsala; Department of Clinical Sciences, Lund University, University Hospital, Malmo; Departmen

Using a molten organic conducting material to infiltrate a nanoporous semiconductor film and its use in solid-state dye-sensitized solar cells

We describe a method to fill thin films of nanoporous TiO2 with solid organic hole-conducting materials and demonstrate the procedure specifically for use in the preparation of dye-sensitized solar cells. Cross-sections of the films were investigated by scanning electron microscopy and it was observed that a hot molten organic material fills pores that are 10 mu m below the surface of the film. We

Mycophenolic Acid Exposure after Administration of Mycophenolate Mofetil in the Presence and Absence of Ciclosporin in Renal Transplant Recipients

Background and objective: The pharmacokinetics of mycophenolic acid (MPA) are complex, with large interindividual variability over time. There are also well documented interactions with ciclosporin, and assessment of MPA exposure is therefore necessary when reducing or stopping ciclosporin therapy. Here we report on the pharmacokinetic and pharmacodynamic behaviour of MPA in renal transplant patie

COD fractionation of palm oil mill effluent: typical treatment, biodegradability and modelling

Activated sludge model (ASM) is now widely used for wastewater treatment plant design, optimization and operation. Values for parameters to be used are vital for the accuracy of the modeling approach. This study aims to establish the scientific link between typical treatment and biodegradability of different chemical oxygen demand (COD) fractionation of palm oil mill effluent (POME), by means of r

Calculation of beach change under interacting cross-shore and longshore processes

This paper presents a mathematical approach and numerical model that simulates beach and dune change in response to cross-shore processes of dune growth by wind and dune erosion by storms, and by gradients in longshore sand transport that will alter shoreline position. Sub-aerial transport processes are represented, whereas sub-aqueous transport is neglected. The system is tightly coupled morpholo

Regulation of human papillomavirus gene expression by splicing and polyadenylation.

Human papillomaviruses (HPVs) are small DNA tumour viruses that are present in more than 99% of all cervical cancers. The ability of these viruses to cause disease is partly attributed to the strict coordination of viral gene expression with the differentiation stage of the infected cell. HPV gene expression is regulated temporally at the level of RNA splicing and polyadenylation, and a dysregulat

Bacterial abundance, production and organic carbon limitation in the Southern Ocean (39-62 degrees S, 4-14 degrees E) during the austral summer 1997/1998

Bacterial abundance and production were studied in different zones in the Southern Ocean (39-62degreesS, 4-14degreesE) during a cruise in December-January 1997/1998. The role of potential growth limitation of bacteria due to limited availability of organic carbon (glucose) or inorganic N and P was studied in parallel. A positive correlation between surface water temperatures (-2 to 18 degreesC) an

Depletion of myocardial glucose is observed during endotoxemic but not hemorrhagic shock in a porcine model

Introduction Metabolic dysfunction is one of the hallmarks of sepsis yet little is known about local changes in key organs such as the heart. The aim of this study was to compare myocardial metabolic changes by direct measurements of substrates, such as glucose, lactate and pyruvate, using microdialysis (MD) in in-vivo porcine endotoxemic and hemorrhagic shock. To assess whether these changes were

Microstructure and water distribution of commercial pasta studied by microscopy and 3D magnetic resonance imaging

Manufacturing pasta is a rather well known process, but it is still challenging to tailor pasta products with new raw materials. In this study, we evaluated the effects of raw materials on the microstructure and water distribution in cooked pasta using H-1 magnetic resonance imaging (MRI) as well as bright field and polarized light microscopy. The MRI parameters initial intensity (I-0) and transve

Experimental insights into the importance of aquatic bacterial community composition to the degradation of dissolved organic matter.

Bacteria play a central role in the cycling of carbon, yet our understanding of the relationship between the taxonomic composition and the degradation of dissolved organic matter (DOM) is still poor. In this experimental study, we were able to demonstrate a direct link between community composition and ecosystem functioning in that differently structured aquatic bacterial communities differed in t

Membrane performance during ultrafiltration of a high-viscosity solution containing hemicelluloses from wheat bran

Hemicelluloses isolated from agricultural residues have the potential to replace fossil-based materials in high-value-added applications, provided that cost-efficient isolation processes are developed. In this study, a feed solution containing hemicelluloses extracted from wheat bran with a particular high viscosity was used to study the performance of ultrafiltration for hemicellulose isolation a

Cars in Transition - An Assessment of Future Vehicle Technologies

The transport sector is facing serious challenges in meeting long-term sustainability criteria. Radical changes in the design of vehicles to attain competitive vehicles with substantially better environmental performance will probably constitute an important part in a future sustainable transport sector. The aim of the study described in this thesis is to assess the long-term options currently und

Leg ulcer management in primary care with special reference to pinch grafting

Popular Abstract in Swedish Kroniska bensår utgör en av våra folksjukdomar, där 1% av befolkningen någon gång drabbas. Uppkomsten av sår kan ha en mängd olika orsaker. Den största gruppen är venösa sår, dvs sådana som orsakats av vensjukdom. Behandling av sår har i långa tider betraktats som komplicerad, då såren ofta varit svårläkta och återkommit efter läkning. För den enskilde patienten innebärWound management in primary and community care was investigated throughout a period of 12 years within a well-defined population in one county in Southern Sweden. The estimated prevalence of chronic leg and foot ulcers was 0.19% in 1998 and the mean prevalence was 0.20% during the years 1994-1998. Venous ulcers were the most common (38%) and 7% of the nurses’ workload was devoted to ulcer care. Du

More than requirements: Applying requirements engineering techniques to the challenge of setting corporate intellectual policy, an experience report

Creation and adoption of corporate policies requires significant commitment of scarce senior management resources. In the absence of processes and tools, convergence upon final policy and may not be achieved in a timely manner. Significant similarities between policy and requirements documents suggest that requirements engineering techniques could be used to generate policy. However, neither evide

Äktenskapsförord - En avtalsrättslig komparation

Förevarande text handlar om skillnaderna mellan äktenskapsförord och förmögenhetsrättsliga avtal. Ett äktenskapsförord är ett familjerättsligt avtal med stark förmögenhetsrättslig prägel. Detta till trots gör sig dock en del typiska familjerättsliga särdrag gällande. Sådana särdrag är exempelvis de olika formkrav som gör sig gällande ifråga om äktenskapsförord. Äktenskapsförord skall upptecknas i This text is about the various differences between prenuptial agreements and contracts dealing with property law. A prenuptial agreement is a contract between partners, with strong economical characteristics. In spite of these characteristics there are some essential differences between the two types of contracts. There are, for instance, more formal requirements to take into consideration concern