Filtyp
Modelling the temperature dynamics of a district heating system is typically validated for a single pipe or a system with limited information about dynamic consumer behaviour. In the present work, time dependent consumer data from the Naestved district heating system was used to investigate the ability of modelling tools to represent the temperature profile distortion throughout an entire heating
A manikin test probe has been developed to simulate the thermal behaviour of human skin when exposed to thermal conditions likely to occur in fires. The threshold for second-degree burn injuries is evaluated from the temperature readings using a damage integral. The probe has been exposed to different radiation fluxes and the calculated damage criterion for second-degree burn injuries is in agreem
The effects of reduced intercellular coupling in the sinus node were investigated by means of simulations. Coupling was reduced both uniformly, and by introducing localized interaction blocks. In either case, model sinus node element networks typically splitted into frequency domains. These were defined as groups of neighbour elements which all attained the same mean firing frequency. In systems,
Objective: Lately, desmopressin (dDAVP) administered orally has been demonstrated to be an effective alternative in the management of nocturia in adults. Although the safety profile of dDAVP is well known, much of the experience originates from studies in enuretic children and younger adults, and it may not be readily extrapolated to elderly patients. In order to identify factors associated with a
A rapid and sensitive assay was developed for the detection of amphetamine in plasma and urine. The method relies on the principle of competitive ELISA (enzyme-linked immunosorbent assay). A flow microchip with a total volume of 7 µL was used for the development of a chemiluminescent ELISA technique. Solutions, samples, and the chemiluminescence substrate were injected by a flow system, and a phot
BACKGROUND: Representing is about theories and theory formation. Philosophy of science has a long-standing interest in representing. At least since Ian Hacking's modern classic Representing and Intervening (1983) analytical philosophers have struggled to combine that interest with a study of the roles of intervention studies. With few exceptions this focus of philosophy of science has been on phys
A new curriculum is planned for the medical school at Lund University, Sweden. Pharmacology, in a broad sense, has been identified as a subject that needs to be strengthened based on needs in the healthcare system. The aim was to identify the competencies in basic and clinical pharmacology that a newly qualified physician needs. Using a modified three-round Delphi technique, 31 physicians were inv
Pressurized liquid extraction is a "green" technology for the extraction of nutraceuticals from foods and herbal plants. This review discusses the extraction principles and the optimization of the extraction parameters that improves the extraction efficiency. The use of different solvent mixtures and other extraction additives to enhance the efficiency of the extraction are discussed. Dynamic mode
There are many good practice examples in sustainable tourism, but the difficulty is how they can be transparently measured, monitored and disseminated. The study aims to develop a measurement system for good practice in sustainable tourism, meanwhile to make some contribution to the monitoring and reporting system. In order to accomplish this, the thesis allocates good practice examples into a Sus
The presence of genes encoding organellar proteins in different cellular compartments necessitates a tight coordination of expression by the different genomes of the eukaryotic cell. This coordination of gene expression is achieved by organelle-to-nucleus communication. Stress-induced perturbations of the tetrapyrrole pathway trigger large changes in nuclear gene expression. In order to investigat
This thesis deals with the information-structural problems native speakers of Swedish have when producing texts in German as their second or foreign language (L2). The study is based on written production data from Swedish learners of German at the initial state (14-year-olds), at intermediate level (16-year-olds) and at advanced level (20-25-year-olds). These data are compared with Swedish and Ge
The EWSR1 gene in chromosome band 22q12 is a promiscuous fusion partner involved in a vast array of tumors characterized by gene fusions. In this study, we report the finding of a new fusion gene, EWSR1-NFATC1, in a hemangioma of the bone; genetic rearrangements have not previously been described in this tumor type. Chromosome banding analysis showed a t(18;22)(q23;q12) translocation as the sole c
Eye tracking was used to investigate the task of assessing how likely it is that one would be able to rest and recover in small urban spaces and how it affects the view pattern. We assess which environmental components, for example, flowers and trees, participants look at when evaluating restoration likelihood. Further, we compare number of fixations in restorative and non-restorative park photos.
Recent evidence suggests that there are serious information asymmetries in the Kenyan financial market. Between 2006 and 2009, the formal and semi-formal financial sectors in Kenya increased a lot. In contrast to what classic economic theories would predict, the informal financial sector experienced a minor increase. This thesis, through interviews in a minor field study, suggests that the informa
HIV/AIDS is not to be looked upon as an entirely medical problem as will be explained throughout this thesis. In Nicaragua it is indeed a social disease due to social and cultural factors leading to the misery of HIV-positive women. Nicaragua is an interesting case when studying HIV/AIDS because it is the Central American country with the lowest number of official reported cases. However there are
Alzheimer’s disease (AD) is a heterogeneous neurodegenerative disease driven by pathological depositions of proteins that accumulate over decades. Compelling genetic and neurobiological evidence suggests that amyloid accumulation in the brain initiates and drives early-stage AD. Measurement of fibrillar amyloid has been pivotal to the development and approval of disease-slowing treatments. Various
BACKGROUND: Non-operative treatment for acute appendicitis (AA) in children has gained acceptance as an alternative to surgery in selected cases. Accurate preoperative differentiation between perforated and non-perforated AA is increasingly important, as the former requires emergency surgery while the latter may be managed conservatively. Previous research has suggested that low plasma sodium conc
