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HIV/AIDS is not to be looked upon as an entirely medical problem as will be explained throughout this thesis. In Nicaragua it is indeed a social disease due to social and cultural factors leading to the misery of HIV-positive women. Nicaragua is an interesting case when studying HIV/AIDS because it is the Central American country with the lowest number of official reported cases. However there are
Alzheimer’s disease (AD) is a heterogeneous neurodegenerative disease driven by pathological depositions of proteins that accumulate over decades. Compelling genetic and neurobiological evidence suggests that amyloid accumulation in the brain initiates and drives early-stage AD. Measurement of fibrillar amyloid has been pivotal to the development and approval of disease-slowing treatments. Various
BACKGROUND: Non-operative treatment for acute appendicitis (AA) in children has gained acceptance as an alternative to surgery in selected cases. Accurate preoperative differentiation between perforated and non-perforated AA is increasingly important, as the former requires emergency surgery while the latter may be managed conservatively. Previous research has suggested that low plasma sodium conc
The Swedish crime genre is experiencing an intense period of change at the moment. Crime writers appear to be at the forefront when it comes to the issue of how to reach international audiences, how to promote books and author’s brands through events, and how to create a successful life as a writer. The working conditions, as well as the content of what is sold and marketed to the readers have gon
This study presents an approach for partitioned fluid-structure interaction (FSI) applied to large structural deformations, where an incompressible turbulent solver is combined with a structural solver. The implementation is based upon two different open-source libraries by using MPI as a parallel communication protocol, the packages and OpenFOAM. FSI is achieved through a strongly-coupled scheme.
BACKGROUND: The Child Health Services in Sweden is a well-attended health promoting setting, and thereby has an important role in promoting healthy living habits in families with young children. Due to lack of national recommendations for health dialogues, a Child Centred Health Dialogue (CCHD) model was developed and tested in two Swedish municipalities. The aim of this study was to explore paren
The stress intensity factor is investigated for a long plane crack with one tip interacting with a strip of graded elastic material. In the strip the material may have a non uniform modulus of elasticity whereas variation of Poisson’s ratio is ignored. The crack length and the body dimensions are assumed to be large compared to the linear extent of the graded region. The crack tip including the gr
The TOI-1130 is a known planetary system around a K-dwarf consisting of a gas giant planet, TOI-1130 c on an 8.4-day orbit that is accompanied by an inner Neptune-sized planet, TOI-1130 b, with an orbital period of 4.1 days. We collected precise radial velocity (RV) measurements of TOI-1130 with the HARPS and PFS spectrographs as part of our ongoing RV follow-up program. We performed a photodynami
AbstractAim: The overall aim of the thesis was to examine the psychosocial effects and family reactions to participation in longitudinal studies with their children at high risk for type 1 diabetes. Additionally, we aimed to develop a shorter form for the children to measure their anxiety when thinking of their risk of developing type 1 diabetes, which could be used in The Environmental Determinan
This study regards a Child Play-and-Learn Area (CPLA) in a library as a third place and investigates its relationships with visitors through the concept of place attachment. To understand the influence of the CPLA, the study examined the relationships among visitors' place attachment, servicescape and behavioural intentions involving place scales. A survey was conducted in a CPLA in Christchurch,
This article examines how the principle of ‘the best interests of the child’, as enshrined in the Convention on the Rights of the Child (CRC), is interpreted, constructed, and applied in court cases involving child custody disputes. These disputes provide a globally relevant example of the CRC’s social dynamics, as they often involve interactions and negotiations among diverse professional groups.
Introduction: To increase the sustainability of healthcare, clinical trials must assess the environmental impact of interventions alongside clinical outcomes. This should be guided by Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) and Consolidated Standards of Reporting Trials (CONSORT) extensions, which will be developed by The Implementing Climate and Environmental O
Background: Patients undergoing allogeneic haematopoietic stem cell transplantation (allo-HCT) often face complex and evolving needs throughout recovery. Person-centred nursing (PCN) is essential in this context yet remains underexplored in specialised care settings. In Sweden, the Assessment of Rehabilitation Needs Checklist (ARNC) is commonly used in cancer care, but its role in supporting perso
IKEA Funabashi has overall proven itself to be successful since its establishment in Japan in 2006. They have chosen to adapt themselves to obligatory cultural aspects while still being able to standardize their products and keep what makes them special – their so-called “Swedishness”. Another reason for their success may be the fact that they do not have any direct competitors. We do however reco
Studies on fluids at supercritical pressure have been developed in a rapid-growth manner so that geometries are not restricted to circular tube. This paper is devoted to conduct a brief review of the recent main experiments on supercritical fluids such as CO 2
The pace-of-life syndrome (POLS) hypothesis predicts that behavior and physiology covary with life history. Evidence for such covariation is contradictory, possibly because systematic sources of variation (e.g. sex) have been neglected. Sexes often experience different selection pressures leading to sex-specific allocation between reproduction and self-maintenance, facilitating divergence in life-
Reactive settling denotes the process of sedimentation of small solid particles dispersed in a viscous fluid with simultaneous reactions between the components that constitute the solid and liquid phases. This process is of particular importance for the simulation and control of secondary settling tanks (SSTs) in water resource recovery facilities (WRRFs), formerly known as wastewater treatment pl
The corona pandemic has put intergenerational relationships in focus in ways previously never experiences. In many national contexts, lockdowns and restrictions have caused forced generational separation in families. In Sweden, the official government standpoint of generational separation – all citizens over 70 were to avoid contact with others, and especially to stay away from interactions with g
Antibodies against a conserved RNA-binding protein, the Ro 60-kDa autoantigen, occur in 24–60% of all patients with systemic lupus erythematosus. Anti-Ro antibodies are correlated with photosensitivity and cutaneous lesions in these patients and with neonatal lupus, a syndrome in which mothers with anti-Ro antibodies give birth to children with complete congenital heart block and photose
Colorectal cancer (CRC) is one of the leading causes of cancer-related mortality worldwide. The current TNM (Tumor, Node, and Metastasis) classification approach is suboptimal in determining the prognosis of CRC patients. The prognosis for CRC is affected by a variety of features that are present at the initial diagnosis. Herein, we performed a systematic exploration and established a novel five-p
