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Reliability of the Turkish version of the European Obstructive Sleep Apnea Screening (EUROSAS) questionnaire for drivers

Purpose: The European Union Driver License Committee recently developed a questionnaire as a screening tool for obstructive sleep apnea (OSA) named the European Obstructive Sleep Apnea Screening (EUROSAS) questionnaire for drivers. We sought to address the reliability of the Turkish version of this questionnaire. Methods: The EUROSAS was translated into Turkish. Using a “test-retest approach”, dat

Dietary Intakes, Patterns, and Determinants of Children Under 5 Years from Marginalized Communities in Odisha: A Cross-sectional Study

Pre-school age (3–5 years) children are vulnerable to malnutrition due to poor dietary intake, dietary habits, and socio-economic conditions. Children from marginalized families are more vulnerable than non-marginalized families due to limited access to health- and nutrition-related services, besides other socio-economic factors. This study was done to assess the dietary intakes, patterns, and det

Three decades of heart transplantation in Scandinavia: long-term follow-up

Aim Heart transplantation (HTx) has become a standard treatment for patients with end-stage heart disease. The aim of this study was to report the long-term outcome after HTx in Scandinavia. Methods and results During the period, 1983-2009,2333 HTxs were performed in 2293 patients (mean age 45 +/- 16 years, range 0-70,78% mate). The main indications for HTx were non-ischaemic cardiomyopathy (50%),

A Risk for Hepatocellular Carcinoma Persists Long-term After Sustained Virologic Response in Patients With Hepatitis C-Associated Liver Cirrhosis

Background. The long-term effect of sustained virologic response (SVR) to antiviral therapy on the risk of developing hepatocellular carcinoma (HCC), liver complications, liver-related death, and overall death in hepatitis C virus (HCV)-infected patients with liver cirrhosis is not fully known. Methods. These risks were evaluated during long-term follow-up in 351 patients with HCV-related cirrhosi

Inverse correlation between alcohol consumption and lymphocyte levels of 8-hydroxydeoxyguanosine in humans

In a cross-sectional study of 115 premenopausal non-smoking women, we examined the relationship between lymphocyte levels of 8-hydroxy-2'-deoxyguanosine (8-oxodGuo) and habitual alcohol consumption. The study was conducted in four different regions of Europe, including Potsdam (Germany), Turin (Italy), Malmo (Sweden) and Granada (Spain). Mean 8-oxodGuo levels differed significantly across study ce

Identification of typical synoptic patterns causing heavy rainfall in the rainy season in Japan by a self-organizing map

In order to systematically and visually understand well-known but qualitative and complex relationships between synoptic fields and heavy rainfall events in Kyushu Islands, southwestern Japan, during the BAIU season, these synoptic fields were classified using the Self-Organizing Map (SOM), which can convert complex non-linear features into simple two-dimensional relationships. It was assumed that

Old pythons stay fit; effects of haematozoan infections on life history traits of a large tropical predator

We document the impact of blood parasite infections caused by Hepatozoon sp. on water python (Liasis fuscus) life history traits such as growth rates, condition, reproductive output and survival. Individual snakes maintained similar among-year parasite loads. Hepatozoon infections affected python growth rate, i.e. snakes suffering from high infection levels exhibited significantly slower growth co

Prognostic implication of baseline PR interval in cardiac resynchronization therapy recipients

BACKGROUND: Prolongation of the baseline ECG PR interval is frequently encountered among cardiac resynchronization therapy (CRT) recipients. There are conflicting data regarding the association of a prolonged PR interval with long-term clinical outcome in this patient group.OBJECTIVE: The purpose of this study was to compare clinical outcomes and response to CRT in patients with normal (<200 ms) v

The Cultural Lexicon of Indo-European in Europe : Quantifying Stability and Change

In this paper, we have investigated, by means of quantitative and statistical methods, stability and change in cultural vocabulary of Indo-European in Europe, with a focus on agriculture. For this purpose we have created a culture vocabulary list with lexical head words, organized into subcategories based on their role and function in a cultural system, the purpose of which is to give a representa

Climate Related Thermal Actions for Reliable Design of Concrete Structures

Popular Abstract in Swedish De flesta av Sveriges cirka 15000 större broar är byggda i betong. Ett problem som kan uppkomma i betongbroar är sprickor, vilka kan bidra till att minska broarnas beständighet och säkerhet. I en del broar har fler sprickor uppkommit på sydsidan än på nordsidan vilket antyder att solen har stor påverkan på dessa broar, eftersom det är den enda faktor som skiljer sig väsWhen the temperature changes in the environment the temperature will also change in a structure. Complex interactions of climate factors affect the temperature changes. When the temperature is varied in a material it will expand or contract, and movements will be produced. If the movements are prevented, stresses may be induced which can contribute to cracks in the structure. Severe cracks have be

A non-functional retinoblastoma tumor suppressor (RB) pathway in premenopausal breast cancer is associated with resistance to tamoxifen.

The retinoblastoma tumor suppressor (RB) is important for retaining cell cycle control and loss of RB function is commonly observed in various malignancies. Experimental and animal studies have shown that RB knockdown in ER+ (estrogen receptor) cell lines and xenografts leads to resistance to tamoxifen, indicating that RB-inactivation could be linked to impaired response to specific cancer treatme

Formation and growth of atmospheric nanoparticles in the eastern Mediterranean : Results from long-term measurements and process simulations

Atmospheric new particle formation (NPF) is a common phenomenon all over the world. In this study we present the longest time series of NPF records in the eastern Mediterranean region by analyzing 10 years of aerosol number size distribution data obtained with a mobility particle sizer. The measurements were performed at the Finokalia environmental research station on Crete, Greece, during the per

Functional analyses of rare genetic variants in complement component C9 identified in patients with age-related macular degeneration

Age-related macular degeneration (AMD) is a progressive disease of the central retina and the leading cause of irreversible vision loss in the western world. The involvement of abnormal complement activation in AMD has been suggested by association of variants in genes encoding complement proteins with disease development. A low-frequency variant (p.P167S) in the complement component C9 (C9) gene

Linking lean to green – energy efficiency as a value stream

Over the past few decades, lean management philosophies have penetrated various sectors of industry. At same time, dynamic environmental, or green, management is needed to succeed in the current green conscious market. Some research has already been conducted on the potential synergy gains of the two management philosophies, since both are known to strive towards efficient use of resources, elimin

Delayed Clinical Manifestation of Parkinson's Disease among Physically Active : Do Participants in a Long-Distance Ski Race Have a Motor Reserve?

Background: Physical activity is associated with reduced risk of Parkinson's disease (PD). The explanations for this association are not completely elucidated. We use long-term PD-incidence data from long-distance skiers to study the relationship between exercise and PD. Objective: We aimed to investigate if physical activity is associated with long-term lower risk of PD and if this association co

Performance of gene expression-based single sample predictors for assessment of clinicopathological subgroups and molecular subtypes in cancers : a case comparison study in non-small cell lung cancer

The development of multigene classifiers for cancer prognosis, treatment prediction, molecular subtypes or clinicopathological groups has been a cornerstone in transcriptomic analyses of human malignancies for nearly two decades. However, many reported classifiers are critically limited by different preprocessing needs like normalization and data centering. In response, a new breed of classifiers,

Prevention and prediction of inhibitor risk.

Summary: Studies of determinants of the development of inhibitory antibodies in patients with haemophilia indicate that this is a complex process involving several factors. The foundation is characterized by the T- and B-cell repertoire and the antigen presenting cells and to elicit an immune response to the deficient factor, a pre-disposing foundation is needed. Hence, in the absence of a certain